Results 51 to 60 of about 182,204 (304)

Kinematics, workspace and singularity analysis of a multi-mode parallel robot

open access: yes, 2017
A family of reconfigurable parallel robots can change motion modes by passing through constraint singularities by locking and releasing some passive joints of the robot.
Chablat, Damien   +2 more
core   +2 more sources

Cable Robot Performance Evaluation by Wrench Exertion Capability [PDF]

open access: yes, 2018
Although cable driven robots are a type of parallel manipulators, the evaluation of their performances cannot be carried out using the performance indices already developed for parallel robots with rigid links.
Boschetti, Giovanni, Trevisani, Alberto
core   +2 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Trajectory planning of a novel lower limb rehabilitation robot for stroke patient passive training

open access: yesAdvances in Mechanical Engineering, 2017
A new applicable sitting/lying lower limb rehabilitation robot is proposed to help stroke patients. It can realize the sitting/lying training postures to fit people in all the rehabilitation stages.
Yongfei Feng   +5 more
doaj   +1 more source

SVITE: A Spike-Based VITE Neuro-Inspired Robot Controller [PDF]

open access: yes, 2013
This paper presents an implementation of a neuro-inspired algorithm called VITE (Vector Integration To End Point) in FPGA in the spikes domain. VITE aims to generate a non-planned trajectory for reaching tasks in robots. The algorithm has been adapted
Domínguez Morales, Manuel Jesús   +4 more
core   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Configuration Design and Size Optimization of a High-Precision Novel Parallel Pointing Mechanism Based on Interference Separation

open access: yesChinese Journal of Mechanical Engineering
Pointing mechanism is widely used in aerospace field, and its pointing accuracy and stability have high requirements. The pointing mechanism will be affected by external interference when it works.
Sen Wang   +5 more
doaj   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Theoretical Analysis and Experiment of the Five DOF Hybrid Robot P(RPR/RP)RR

open access: yesIEEE Access
To meet the demands of machining new energy vehicles aluminum alloy structures, this paper introduced a five degree-of-freedom (DOF) hybrid robot, P(RPR/RP)RR, and conducted a systematic investigation into its kinematics, stiffness, and preliminary ...
Xuejian Ma   +4 more
doaj   +1 more source

Actuation Spaces Synthesis of Lower-Mobility Parallel Mechanisms Based on Screw Theory

open access: yesChinese Journal of Mechanical Engineering, 2021
The lower-mobility parallel mechanism has been widely used in the engineering field due to its numerous excellent characteristics. However, little work has been devoted to the actuator selection and placement that best satisfy the system’s functional ...
Shihua Li   +3 more
doaj   +1 more source

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