Results 71 to 80 of about 89,325 (290)
Advanced Science, EarlyView.Single‐cell profiling and functional perturbation reveal coordinated JAK1‐pSTAT3 downstream programs in optic neuritis, including MCL1‐dependent fitness of pathogenic CD4+ Tem cells and glycolysis‐linked, cholesterol‐sensitive B‐cell responses associated with RORA. Upadacitinib disrupts this reciprocal T‐B‐cell circuit and alleviates neuroinflammation,
Gengchen Jiang +12 more
wiley +1 more source
Scientia Marina, 2013 This study reports the accumulation of paralytic shellfish toxins (PSTs) in Atlantic horse mackerel (Trachurus trachurus) over a bloom of the toxigenic dinoflagellate Gymnodinium catenatum. High levels of toxins, up to 4800 μg STXeq kg–1, were registered
Sandra Lage, Pedro Reis Costa
doaj +1 more source
Avaliação da filtração em margem como pré-tratamento à filtração direta descendente na remoção de células de cianobactérias e saxitoxinas [PDF]
, 2012 Tese (doutorado) - Universidade Federal de Santa Catarina, Centro Tecnológico, Programa de Pós-Graduação em Engenharia Ambiental, Florianópolis, 2009.Currently, water treatment plants, which utilize downflow direct filtration technology, have been facing
Mondardo, Renata Iza
core
Advanced Science, EarlyView.Biomarker‐triggered nanoplatforms transform sepsis therapy by coupling pathological sensing with precision drug release. This review reveals how microenvironment‐responsive nanomedicines enable stage‐specific intervention, improve therapeutic efficacy, and minimize systemic toxicity, while highlighting emerging opportunities for AI‐assisted and ...
Yukun Liu +7 more
wiley +1 more source
Advanced Science, EarlyView.Nebulized BN@NF nanozymes integrate boron nanosheets with Nd‐doped iron phosphide to form a sono‐magneto‐responsive Z‐scheme heterostructure. Under ultrasound and magnetic activation, BN@NF amplifies ROS generation, eradicates bacteria, disrupts biofilms, and reshapes pulmonary inflammation through NF‐κB suppression, mitophagy promotion, and M1‐to‐M2 ...
Xiaofeng Luo +6 more
wiley +1 more source
Marine Drugs, 2011 Mouse bioassay is the official testing method to quantify paralytic shellfish toxins (PSTs) in bivalves. A number of alternative analytical methods have been reported. Some methods have been evaluated by a single laboratory validation.
Toshiyuki Suzuki +2 more
doaj +1 more source
Warm temperature acclimation impacts metabolism of paralytic shellfish toxins from Alexandrium minutum in commercial oysters [PDF]
, 2015 © 2015 John Wiley & Sons Ltd. Species of Alexandrium produce potent neurotoxins termed paralytic shellfish toxins and are expanding their ranges worldwide, concurrent with increases in sea surface temperature.
Anthony Zammit +13 more
core +1 more source
Fluorescent Hydrogel‐Based Strain Sensor With Machine Learning‐Augmented Performance
Advanced Intelligent Discovery, EarlyView.Fluorescent hydrogel strain sensor based on carbon quantum dots enabling optical readout of deformation through strain‐dependent emission changes, coupled with Random Forest analysis to capture nonlinear fluorescence‐concentration relationships and identify optimal sensing conditions. Hydrogels are ideal matrices for bio‐integrated wearable sensors due
Tailai Chen +4 more
wiley +1 more source
Blood SOD1 Activity in ALS Patients Receiving Tofersen Treatment
Annals of Neurology, EarlyView.Objective The antisense oligonucleotide tofersen is the first disease‐modifying drug for SOD1‐related amyotrophic lateral sclerosis (ALS) and was approved because of its ability to reduce SOD1 protein and neurofilament levels. The effect of tofersen on SOD1 activity is unclear but of clinical relevance because homozygous SOD1 mutations, linked to ...
Katharina Goehring +18 more
wiley +1 more source
, 2017 Paralytic shellfish poisoning toxins (PST) are a group of neurotoxins produced by dinoflagellate belonging to genera Alexandrium and Gymnodinium. The accumulation of these toxins in seafood represent a major concern to humans since following ingestion of
Samuela Capellacci +6 more
core