Results 41 to 50 of about 5,226 (177)

From Mechanisms to Materials: Oximate Reactivity and Emerging Strategies for Organophosphate Detoxification

open access: yesChemPhysChem, Volume 27, Issue 7, 14 April 2026.
The development of effective strategies for the detoxification of organophosphorus (OP) nerve agents has evolved from the early mechanistic studies of François Terrier and collaborators, who first elucidated the exceptional nucleophilicity of α‐effect species such as oximes and hydroxamates, to the modern design of supramolecular and material‐based ...
Pedro Rodríguez‐Dafonte
wiley   +1 more source

Imidazole aldoximes effective in assisting butyrylcholinesterase catalysis of organophosphate detoxification. [PDF]

open access: yes, 2014
Intoxication by organophosphate (OP) nerve agents and pesticides should be addressed by efficient, quickly deployable countermeasures such as antidotes reactivating acetylcholinesterase or scavenging the parent OP.
Amitai, Gabriel   +5 more
core  

Gold Nanoparticles–Dynamic Constitutional Frameworks as Adaptive Hybrid Conjugates for Enzyme Immobilization

open access: yesChemistryEurope, Volume 4, Issue 4, April 2026.
Dynamic constitutional frameworks (DCFs) and gold nanoparticles (AuNps) assemble into larger and well‐distributed conjugates providing an efficient platform for biosensing and biocatalytic applications. Dynamic constitutional frameworks (DCFs), connecting monomers via reversible covalent bonds, can initiate the assembly of gold nanoparticles (AuNps ...
Sanaa Daakour   +5 more
wiley   +1 more source

Supercharged Phosphotriesterase for improved Paraoxon activity

open access: yesProtein Engineering, Design and Selection
Abstract Phosphotriesterases (PTEs) represent a class of enzymes capable of efficient neutralization of organophosphates (OPs), a dangerous class of neurotoxic chemicals. PTEs suffer from low catalytic activity, particularly at higher temperatures, due to low thermostability and low solubility.
Jacob Kronenberg   +9 more
openaire   +3 more sources

Regulation of the juvenile hormone titre in the Colorado potato beetle [PDF]

open access: yes, 1978
Three main topics were investigated in regulation of the titre of juvenile hormone in haemolymph of the Colorado potato beetle ( Leptinotarsa decemlineata Say): enzymic breakdown of the hormone; binding and protection of the hormone by carrier proteins ...
Kramer, S.J.
core   +1 more source

Directed Protein Packaging within Outer Membrane Vesicles from Escherichia coli: Design, Production and Purification [PDF]

open access: yes, 2016
A protocol for the production, purification, and use of enzyme packaged outer membrane vesicles (OMV) providing for enhanced enzyme stability for implementation across diverse applications is ...
Alves, Nathan J.   +2 more
core   +1 more source

Selection, counterselection, and conditional gene expression for genetic biocontrol of insects

open access: yesInsect Science, Volume 33, Issue 2, Page 724-743, April 2026.
Selection, counterselection, and conditional expression can be used for sex separation. Selection (S) and counterselection (CS) genes are linked to the sex chromosomes (e.g., the X and Y chromosomes) to confer sex‐specific selection or counterselection based on the presence or absence of the S or CS genes.
Melanie Hempel, Zhijian Tu
wiley   +1 more source

Analysis of techniques to obtain plasma for measurement of levels of free fatty acids

open access: yesJournal of Lipid Research, 1993
Accuracy in measurement of plasma free fatty acids (FFA), and therefore prevention of the in vitro lipolysis, is a crucial step to understand the physiologic role of plasma FFA and their relationships in the pathogenesis of important metabolic disorders ...
A Zambon, SI Hashimoto, JD Brunzell
doaj   +1 more source

Solvent Deuterium Oxide Isotope Effects on the Reactions of Organophosphorylated Acetylcholinesterase

open access: yesMolecules, 2020
Organophosphates (OPs) are esters of substituted phosphates, phosphonates or phosphoramidates that react with acetylcholinesterase (AChE) by initially transferring the organophosphityl group to a serine residue in the enzyme active site, concomitant with
Terrone L. Rosenberry
doaj   +1 more source

Assessment of fall‐back MRLs for revoked CXLs previously implemented in the EU legislation

open access: yesEFSA Journal, Volume 24, Issue 4, April 2026.
Abstract In the 56th meeting of the Codex Committee on Pesticide Residues (CCPR meeting) held in September 2025 and the subsequent 48th meeting of the Codex Alimentarius Commission (CAC) (November 2025), 352 Codex MRLs (CXLs) for 30 active substances (a.s.) were revoked.
European Food Safety Authority (EFSA)
wiley   +1 more source

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