Results 51 to 60 of about 5,226 (177)

Inhibition of recombinant human carboxylesterase 1 and 2 and monoacylglycerol lipase by chlorpyrifos oxon, paraoxon and methyl paraoxon [PDF]

Toxicology and Applied Pharmacology, 2012
Oxons are the bioactivated metabolites of organophosphorus insecticides formed via cytochrome P450 monooxygenase-catalyzed desulfuration of the parent compound. Oxons react covalently with the active site serine residue of serine hydrolases, thereby inactivating the enzyme.
J Allen, Crow, Victoria, Bittles, Katye L, Herring, Abdolsamad, Borazjani, Philip M, Potter, Matthew K, Ross   +5 more
openaire   +2 more sources

Agonists of CB1 and NMDA receptors decrease the toxic effect of organophosphorus compound paraoxon on PC12 cells [PDF]

The Ukrainian Biochemical Journal, 2019
Pharmacological studies allow to suggest that activation of cannabinoid type 1 receptors (CB1) have a neuroprotective role against toxicity induced by organophosphate agents, but the exact mechanisms of this effect as well as interaction with receptors ...
F. Salem, F. Bahrami, Z. Bahari, Z. Jangravi, S. Najafizadeh-Sari   +4 more
doaj   +1 more source

Catalytic Amyloids: Turning Fibrils Into Biocatalysts

Chemistry – A European Journal, Volume 32, Issue 10, 9 March 2026.
Amyloids, traditionally associated with diseases, have emerged as versatile catalytic scaffolds. From natural amyloid sequences to bioinspired and de novo designs, we highlight strategies to construct catalytic active sites and anchor enzymes onto fibrils, creating versatile nanomaterials with tunable activities. ABSTRACT Amyloids have been regarded as
Alessandra Esposito, Linda Leone, Flavia Nastri, Angela Lombardi   +3 more
wiley   +1 more source

Effects of high sucrose diet, gemfibrozil, and their combination on plasma paraoxonase 1 activity and lipid levels in rats [PDF]

, 2010
We investigated the influence of high sucrose diet (HSD) after 3 or 5 weeks of administration on paraoxonase 1 (PON1) activity in plasma of normolipidemic rats and the relationship between serum PON1 activity, triacylglycerides (TGs), HDL and total ...
Bradamante, Vlasta, Lucić Vrdoljak, Ana, Macan, Marija, Radić, Božica, Vrkić, Nada   +4 more
core  

Micro/nanorobots for detecting and eliminating biological and chemical warfare agents

BMEMat, Volume 4, Issue 1, March 2026.
Fuel‐powered and field‐driven micro/nanorobots provide a cutting‐edge platform to safeguard national security and defense. This review reports the latest research progress in micro/nanorobots in sensing and detoxifying biological and chemical warfare agents.
Song Li, Huaijuan Zhou, Di Shi, Zdeněk Sofer, Jinhua Li   +4 more
wiley   +1 more source

Critical role of neutral cholesteryl ester hydrolase 1 in cholesteryl ester hydrolysis in murine macrophages[S]

Journal of Lipid Research, 2014
Hydrolysis of intracellular cholesteryl ester (CE) is the rate-limiting step in the efflux of cholesterol from macrophage foam cells. In mouse peritoneal macrophages (MPMs), this process is thought to involve several enzymes: hormone-sensitive lipase ...
Kent Sakai, Masaki Igarashi, Daisuke Yamamuro, Taichi Ohshiro, Shuichi Nagashima, Manabu Takahashi, Bolormaa Enkhtuvshin, Motohiro Sekiya, Hiroaki Okazaki, Jun-ichi Osuga, Shun Ishibashi   +10 more
doaj   +1 more source

An Enzyme-Based Biosensor for the Detection of Organophosphate Compounds Using Mutant Phosphotriesterase Immobilized onto Reduced Graphene Oxide

Journal of Chemistry, 2021
Enzymatic detection of organophosphate (OP) compounds can be tailored using highly sensitive and selective enzymes in the development of biosensors.
Muhammad Syafiq Mohd Razib, Wahhida Latip, Jahwarhar Izuan Abdul Rashid, Victor Feizal Knight, Wan Md Zin Wan Yunus, Keat Khim Ong, Noor Azilah Mohd Kasim, Siti Aminah Mohd Noor   +7 more
doaj   +1 more source

Microengine-assisted electrochemical measurements at printable sensor strips [PDF]

, 2015
A new microengine-based built-in-platform exploiting a surprising dual action with solution mixing and control of the reaction parameters, has been applied for accelerating chemical reactions (organophosphorous nerve agents hydrolysis) and ...
Cinti, Stefano, Gao, Wei, Li, Jinxing, Palleschi, Giuseppe, Valdés-Ramírez, Gabriela, Wang, Joseph   +5 more
core   +1 more source

Real‐time quality and safety monitoring of fruit juice using paper‐based platform

Food Biomacromolecules, Volume 3, Issue 1, Page 140-162, March 2026.
Schematic illustration of a paper‐based biosensor for rapid detection of fruit juice spoilage. Abstract Food spoilage and safety concerns still remain critically challenging within the fruit juice industry, especially as conventional detection methods, though precise, are often too time‐consuming, costly, and reliant on centralized laboratories.
Priti Das, Srushti Bhoite, Noopur Patil, Shubhro Chakrabartty, Debjani Dutta   +4 more
wiley   +1 more source

Purification and characterization of paraoxon hydrolase from rat liver [PDF]

Biochemical Journal, 1997
Paraoxonase (paraoxon hydrolase), an enzyme that hydrolyses paraoxon (O,O-diethyl O-p-nitrophenyl phosphate), is located in mammals primarily in the serum and liver. Although considerable information is available regarding serum paraoxonase, little is known about the hepatic form of this enzyme.
L, Rodrigo, F, Gil, A F, Hernandez, A, Marina, J, Vazquez, A, Pla   +5 more
openaire   +2 more sources