Influence of paraoxonase-1 Q192R and cytochrome P450 2C19 polymorphisms on clopidogrel response
, 2012 Rolf P Kreutz1,2, Perry Nystrom2, Yvonne Kreutz2, Jia Miao2, Zeruesenay Desta2, Jeffrey A Breall1, Lang Li2, ChienWei Chiang2, Richard Kovacs1, David A Flockhart2, Yan Jin21Krannert Institute of Cardiology, 2Division of Clinical Pharmacology, Indiana ...
Breall JA +10 more
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Human Paraoxonase-1 Activity in Children with Acute Bronchiolitis
, 2020 INTRODUCTION: Human paraoxonase-1 (PON1) is one of the endogenous antioxidant molecules working against oxidative stress.
ERENBERK U. +5 more
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Association of Paraoxonase 1 Gene Polymorphism and Enzyme Activity With Carotid Plaque in Rheumatoid Arthritis [PDF]
, 2013 OBJECTIVE: To investigate the relationship of genetic and biochemical determinants of paraoxonase 1 activity to carotid plaque as a surrogate marker of cardiovascular (CV) risk in patients with rheumatoid arthritis (RA).
FitzGerald, John +10 more
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Lower paraoxonase 1 activity in Tunisian bipolar I patients
, 2010 Background The purpose of this study was to investigate the variations of paraoxonase activity and lipid profile in bipolar I patients, and the association of this activity with the sociodemographic, clinical and therapeutic characteristics of this ...
Mouhamed Dhouha +7 more
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Molecular Oncology, Volume 20, Issue S1, Page 1-692, August 2026.Abstracts submitted to the ‘EACR 2026 Congress: Innovative Cancer Science’, from 08–11 June 2026 and accepted by the Congress Organising Committee are published in this Supplement of Molecular Oncology, an affiliated journal of the European Association for Cancer Research (EACR).
wiley +1 more source
Paraoxonase-1 and linoleic acid oxidation in familial hypercholesterolemia. [PDF]
, 2005 Contains fulltext : 49079.pdf (Publisher’s version ) (Closed access)Serum paraoxonase-1 (PON1) is a high-density lipoprotein-associated enzyme that can inhibit low-density lipoprotein (LDL) oxidation in vitro.
Himbergen, T.M. van +5 more
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The Effect of Pomegranate Juice Supplementation on Oxidative Stress in Young Healthy Males [PDF]
Background & Objectives: The intake of antioxidant supplementations can have key role in prevention of oxidative stress in healthy individuals. Pomegranate has antioxidant effects and may play a role in reduction of oxidative stress in healthy males ...
نعمتی, علی +3 more
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Paraoxonase-1 and Early-Life Environmental Exposures
Annals of Global Health, 2016 Acute and chronic exposures to widely used organophosphorus (OP) insecticides are common. Children's detoxification mechanisms are not well developed until several years after birth. The increased cases of neurodevelopmental disorders in children, together with their increased susceptibility to OP neurotoxicity cannot be explained by genetic factors ...
Marsillach, Judit +2 more
openaire +5 more sources
ASSOCIATION BETWEEN THE SEVERITY OF ANGIOGRAPHIC CORONARY ARTERY DISEASE AND PARAOXONASE-1 PROMOTER GENE POLYMORPHISM T(-107)C IN IRANIAN POPULATION [PDF]
Acta Medica Iranica, 2008 The oxidation of low-density lipoproteins and cell membrane lipids is believed to play an integral role in the development of fatty streak lesions, an initial step in coronary artery disease (CAD).
A. Jalilian +5 more
doaj +2 more sources
IMPACT OF CARBAZOLE P-LACTAM DERIVATIVES ON PARAOXONASE-1 ACTIVITY
, 2017 Paraoxonase 1 (PON1) is an antioxidant enzyme associated with high-density lipoproteins (HDL). PON1 has the ability to inhibit lipid peroxides and to hydrolyze a wide variety of substrates such as esters, thioesters, phosphotriesterases, carbonates ...
Arlinda Bytyqi-Damoni +5 more
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