Results 101 to 110 of about 406,905 (221)

Mapping Projectome Heterogeneity of Subiculum Neuron Cell Types

Hippocampus, Volume 36, Issue 6, November 2026.
ABSTRACT The subiculum (SUB) is the main output structure of the hippocampus, influencing diverse behaviors through its widespread cortical and subcortical connections. Our previous work creating the mouse Hippocampus Gene Expression Atlas (HGEA) identified four genetically distinct cellular layers across five columnar domains in the SUB, with gene ...
Ann W. Saustad, Michael S. Bienkowski
wiley   +1 more source

Nicotinic cholinergic activation of magnocellular neurons of the hypothalamic paraventricular nucleus

, 2002
The aim of the present work was to determine whether paraventricular neurons possess functional acetylcholine nicotinic receptors. Using infrared videomicroscopy and differential interference contrast optics, we performed whole-cell recordings in ...
Zaninetti, M., Bertrand, Daniel, Tribollet, Eliane, Raggenbass, Mario   +3 more
core   +2 more sources

Chronic stress activates a hypothalamic vagal circuit to promote hepatocellular carcinoma progression in male mice

Nature Communications
Hepatocellular carcinoma and depression frequently co-occur, yet the mechanisms linking them remain unclear. Here, we show that chronic stress, systemic inflammation, or neuropathic pain are associated with hepatocellular carcinoma progression in male ...
Kun Zhang, Jianxing Zhang, Dongmei Chi, Zhaoli He, Sudena Wang, Xitong Zheng, Rongping Guo, Weian Zeng, Handong Ouyang, Chaopeng Ou, Xiaohui Bai   +10 more
doaj   +1 more source

Paraventricular Hypothalamic Nucleus Upregulates Intraocular Pressure Via Glutamatergic Neurons. [PDF]

Invest Ophthalmol Vis Sci, 2023
Ma L, Liu Q, Liu X, Chang H, Jin S, Ma W, Xu F, Liu H.   +7 more
europepmc   +1 more source

Physiological Mapping of Local Inhibitory Inputs to the Hypothalamic Paraventricular Nucleus

, 1996
Local inhibitory synaptic inputs to neurons of the rat hypothalamic paraventricular nucleus (PVN) were studied by using glutamate microstimulation and conventional intracellular and whole-cell patch-clamp recordings in coronal, horizontal, and ...
Cherif Boudaba, Kriszta Szabó, Jeffrey G. Tasker   +2 more
core   +1 more source

A Cilia–Centered Nicotinamide Adenine Dinucleotide (NAD+) Signaling Network Regulates Hypothalamic Lysosomal Homeostasis and Metabolic Aging

Aging Cell, Volume 25, Issue 11, November 2026.
Aging‐associated NAD+ depletion in hypothalamic neurons shortens primary cilia and disrupts CHMP4B trafficking to lysosomes during lysosomal stress, leading to impaired TRPML1–mediated Ca2+ signaling and lysosomal stress responses. Calorie restriction restores hypothalamic NAD+ levels, ciliary structure, and lysosomal homeostasis, thereby improving ...
Se Eun Park, Eun Roh, Jae Woo Park, Seong Jun Kim, So Yeon Jeong, Chae Beom Park, Hyo Sun Lim, Ji Soo Kim, Mun Gyeom Kim, Myeong Ju Kim, Young In Cho, Wontae Jeong, Gil Myoung Kang, Sang‐Yeob Kim, Se Hee Min, Min‐Seon Kim   +15 more
wiley   +1 more source

GABA(B) receptor-activation inhibits GABAergic synaptic transmission in parvocellular neurones of rat hypothalamic paraventricular nucleus

, 2006
The paraventricular nucleus of the hypothalamus contains three classes of neurones: (i) magnocellular and (ii) parvocellular neurosecretory neurones and (iii) nonendocrine projection neurones.
Liu, X., Tribollet, Eliane, Raggenbass, Mario   +2 more
core   +1 more source

Voluntary exercise mitigates the effects of peri‐adolescent social isolation on emotion recognition and the oxytocinergic system in male mice

Journal of Neuroendocrinology, Volume 38, Issue 11, November 2026.
Abstract Social isolation, particularly during adolescence, is known to affect cognitive, emotional, and social behaviors as well as brain modulatory systems such as the hypothalamic oxytocinergic system. Interestingly, recent evidence indicates that exercise can exert beneficial effects on behaviors through the activation of the oxytocinergic system ...
E. Van Loveren, S. Alfos, S. F. Guu, C. Ducroix‐Crepy, S. Hernández‐Ramírez, G. Ferreira, P. Lafenetre   +6 more
wiley   +1 more source

Neuroendorine and epigentic mechanisms subserving autonomic imbalance and HPA dysfunction in the metabolic syndrome

Frontiers in Neuroscience, 2016
Impact of environmental stress upon pathophysiology of the metabolic syndrome (MetS) has been substantiated by epidemiological, psychophysiological, and endocrinological studies.
Erwin eLemche, Oleg S. Chaban, Alexandra V. Lemche   +2 more
doaj   +1 more source

Differential hypothalamic neuronal activation following peripheral injection of GLP-1 and oxyntomodulin in mice detected by manganese-enhanced magnetic resonance imaging

, 2006
The anorexigenic gut hormones oxyntomodulin (OXM) and glucagon-like peptide-1 (GLP-1) are thought to physiologically regulate appetite and food intake.
Parkinson, J.R.C., Kuo, Y.T., Stanley, S.A., Bloom, S.R., Chaudhri, O.B., Dhillo, W.S., Druce, M.R., Bell, J.D., Herlihy, A.H., Ghatei, M.A.   +9 more
core   +1 more source