Results 91 to 100 of about 20,521 (195)

A mini‐review of chronic suppression of the hypothalamic–pituitary–adrenal axis in animals with P‐glycoprotein deficiency

Journal of Small Animal Practice, Volume 67, Issue 6, Page 487-491, June 2026.
This mini‐review describes the pathophysiology of the disrupted hypothalamic–pituitary–adrenal axis in dogs, and probably cats, with the MDR1 (ABCB1) mutation, ABCB1‐1Δ in dogs and ABCB11930‐1931del TC in cats. Clinical consequences in affected animals are discussed and therapeutic interventions to consider are presented.
K. L. Mealey
wiley   +1 more source

Unraveling the Dynamics of Oxytocin in Hypothalamic Neurons

Traffic, Volume 27, Issue 2, June 2026.
Oxytocin (OT) plays an important role in regulating social behavior, and dysregulation of the oxytocinergic system leads to social impairments, such as autism spectrum disorder. Central OT release is poorly understood. Using live‐cell imaging to track vesicle trajectories, combined with machine learning‐based classification, the analysis reveals ...
Beatriz Aznar‐Escolano, Vera Egorova, José Villanueva, Luis Miguel Gutiérrez, Virginia González‐Vélez, Amparo Gil, Sandra Jurado   +6 more
wiley   +1 more source

Adenosine Downregulates the Activities of Glutamatergic Neurons in the Paraventricular Hypothalamic Nucleus Required for Sleep. [PDF]

Front Neurosci, 2022
Chen C, Lin Y, Cai F, Li J, Li H, Li X.
europepmc   +1 more source

Early adversity and the comorbidity between metabolic disease and psychopathology

The Journal of Physiology, Volume 604, Issue 11, Page 4338-4377, 1 June 2026.
Abstract figure legend Hierarchical diagram representing the interplay between the genetic background and early life adversities and its effect on multiple physiological processes that ultimately impact on the risk for the comorbdity between psychopathology and cardiometabolic disorders.
Ameyalli Gómez‐Ilescas, Patricia Pelufo Silveira   +1 more
wiley   +1 more source

Alpha-synuclein expression in oxytocin neurons of young and old bovine brains

The Journal of Reproduction and Development
Understanding of central nervous system mechanisms underlying age-related infertility remains limited. Fibril α-synuclein, distinct from its monomeric form, is implicated in age-related diseases. Notably, fibril α-synuclein spreads among neurons,
Yvan Bienvenu NIYONZIMA, Yuuki ASATO, Hiroya KADOKAWA   +2 more
doaj   +1 more source

Elevated Glucagon-like Peptide-1 Receptor Level in the Paraventricular Hypothalamic Nucleus of Type 2 Diabetes Mellitus Patients. [PDF]

Int J Mol Sci, 2022
Renner É, Dóra F, Oszwald E, Dobolyi Á, Palkovits M.   +4 more
europepmc   +1 more source

Pituitary Neurolobectomy induces sustained hypotension in male Wistar rats and normalizes blood pressure in male spontaneously hypertensive rats

Physiological Reports, Volume 14, Issue 11, June 2026.
Abstract Arginine vasopressin is primarily recognized as an osmoregulatory hormone; however, its contribution to vascular tone and blood pressure regulation under basal and hypertensive conditions remains debated. This study examined the effects of vasopressin deficiency induced by neurointermediate pituitary lobectomy in Wistar and spontaneously ...
Gloria Marcela Villanueva‐Rodríguez, Norma A. Bobadilla, J. Luis Quintanar, Claudia Verónica Rivera‐Cerecedo, David Roberto Chavira‐Ramírez, Kalman Kovacs, Andrés Quintanar‐Stephano   +6 more
wiley   +1 more source

Case Report: Dysfunction of the Paraventricular Hypothalamic Nucleus Area Induces Hypersomnia in Patients. [PDF]

Front Neurosci, 2022
Wang Z, Zhong YH, Jiang S, Qu WM, Huang ZL, Chen CR.   +5 more
europepmc   +1 more source

Activity‐based anorexia enhances glutamatergic synaptic transmission and neuronal excitability within the nucleus accumbens of female mice

Physiological Reports, Volume 14, Issue 11, June 2026.
Abstract Anorexia nervosa is a severe psychiatric disorder characterized by persistent food restriction and often excessive physical activity, implicating dysfunction in neural circuits governing motivation, reward, and behavioral persistence. The nucleus accumbens (NAc) is a central component of these circuits, yet synaptic and cellular adaptations ...
Lydia G. Bailey, Connor W. Christensen, Samantha E. Weed, Mohammed Moinul Islam, Amit Thakar, Jaedyn B. Brown, Shane T. Hentges, Travis E. Brown   +7 more
wiley   +1 more source

A paraventricular hypothalamic nucleus input to ventral of lateral septal nucleus controls chronic visceral pain. [PDF]

Pain, 2023
Li YC, Wang Q, Li MG, Hu SF, Xu GY.
europepmc   +1 more source