Results 81 to 90 of about 20,521 (195)

Cilia in Nervous System Development, Function, and Disease

MedComm – Future Medicine, Volume 5, Issue 2, June 2026.
Cilia are evolutionarily conserved organelles that function as essential sensory and motility platforms in the nervous system. This review outlines key cilia‐dependent signaling pathways and their roles in neural development and function. Furthermore, it highlights how ciliary dysfunction can lead to a variety of neurological disorders, known as ...
Qingchao Li, Anqi Zhang, Ting Song
wiley   +1 more source

Clozapine impact on FosB/ΔFosB expression in stress preconditioned rats: response to a novel stressor

Endocrine Regulations, 2019
Objective. Prolonged treatment with neuroleptics has been shown to induce FosB/ΔFosB expression in several brain regions including the medial prefrontal cortex, dorsomedial and dorsolateral striatum, ventrolateral and dorsolateral septum, nucleus ...
Osacka Jana, Horvathova Lubica, Cernackova Alena, Kiss Alexander   +3 more
doaj   +1 more source

Heartfelt intervention: A role for PVN oxytocin neurons in the prediabetic heart

The Journal of Physiology, EarlyView.
Grace K. Nielsen, Reesa M. Wilcox, Han‐Jun Wang   +2 more
wiley   +1 more source

Glucose‐dependent insulinotropic polypeptide receptor systems in the hypothalamus and the brainstem regulate feeding and weight through distinct pathways

Journal of Diabetes Investigation
The report by Adriaenssens et al. in JCI Insight 22 May 2023 explored the role and property of the neurons that express glucose‐dependent insulinotropic polypeptide receptor (GIPR) in the brainstem and hypothalamus.
Toshihiko Yada
doaj   +1 more source

Paraventricular Hypothalamic Nucleus Upregulates Intraocular Pressure Via Glutamatergic Neurons. [PDF]

Invest Ophthalmol Vis Sci, 2023
Ma L, Liu Q, Liu X, Chang H, Jin S, Ma W, Xu F, Liu H.   +7 more
europepmc   +1 more source

Next‐Generation Strategies for Neural Repair and Regeneration: Neural Organoid Transplantation in the CNS

Cell Proliferation, Volume 59, Issue 6, June 2026.
Neurological disorders are hard to treat. Stem cell‐derived neural organoids enable research, and their transplantation aids CNS therapy, with this article reviewing relevant advances, challenges and prospects. ABSTRACT Neurological disorders are often devastating and notoriously difficult to repair, creating an urgent need for novel research models ...
Yutong Wang, Jinrui Li, Xingjia Mao, Wanyu Wang, Yansong Li, Xuefei Hu, Jinjie Zhong, Fengdong Zhao, Linlin Wang   +8 more
wiley   +1 more source

Intravenous Oxytocin Has no Effect on Ad Libitum Food Intake or Postprandial Plasma Glucose Concentrations in Individuals With Obesity: A Randomised, Placebo‐Controlled, Double‐Blind, Crossover Study

Diabetes, Obesity and Metabolism, Volume 28, Issue 6, Page 4671-4682, June 2026.
ABSTRACT Introduction Oxytocin is expressed throughout the small intestine, suggesting a role for oxytocin in postprandial metabolism. Accordingly, single‐dose intranasal oxytocin reduces food intake and improves glucose tolerance. We investigated the effects of a continuous intravenous oxytocin infusion on ad libitum food intake, appetite sensations ...
Ida M. Gether, Vivian Kliim‐Hansen, Petur T. Olafsson, Miriam G. Pedersen, Casper K. Nielsen, Anne‐Marie Ellegaard, Mikkel B. Christensen, Jens F. Rehfeld, Jørn W. Helge, Jens J. Holst, Bolette Hartmann, Filip K. Knop, Lærke S. Gasbjerg, Asger B. Lund   +13 more
wiley   +1 more source

Energy deficiency promotes rhythmic foraging behavior by activating neurons in paraventricular hypothalamic nucleus. [PDF]

Front Nutr, 2023
Wu S, Wang J, Xu Y, Zhang Z, Jin X, Liang Y, Ge Y, Zhan H, Peng L, Luo D, Li M, Bi W, Guan Q, He Z.   +13 more
europepmc   +1 more source

Norepinephrine applied in the paraventricular hypothalamic nucleus stimulates vasopressin release

Brain Research, 1986
The present experiments were designed to investigate the effect of norepinephrine (NE) applied directly in the area of the paraventricular nucleus (PVN) of the hypothalamus on arginine-vasopressin (AVP) release and blood pressure. A microinjection of 0.4 micrograms NE in the PNV produced a plasma AVP level of 26.3 +/- 5.3 pg/ml compared to 5.3 +/- 0.6 ...
A, Benetos, I, Gavras, H, Gavras
openaire   +2 more sources

KNDy kisspeptin is required for metabolic homeostasis in female mice in an ovarian hormone‐independent manner

Journal of Neuroendocrinology, Volume 38, Issue 6, June 2026.
Abstract Disorders of gonadotropin pulsatility contribute to reproductive dysfunction in humans and are often associated with metabolic dysfunction. Hypogonadotropic hypogonadism is characterized by chronically insufficient gonadotropin hormone production, leading to reproductive and metabolic impairments, such as infertility and obesity.
Nimisha Nandankar, Ariel L. Negrón, Harshini Ganesh, Natalia Youssef, Saad Farooq, Sarmed Al‐Samerria, Jon E. Levine, Sally Radovick   +7 more
wiley   +1 more source