Results 81 to 90 of about 406,905 (221)

Central oxytocin and food intake: focus on macronutrient-driven reward [PDF]

, 2015
Centrally acting oxytocin (OT) is known to terminate food consumption in response to excessive stomach distension, increase in salt loading, and presence of toxins.
Klockars, Anica, Pawel Karol Olszewski, Levine, Allen S., Allen Stuart Levine, Anica Klockars, Anica eKlockars, Olszewski, Pawel K., Levine, Allen Stuart   +7 more
core   +1 more source

Glucocorticoids and HPA axis regulation in the stress–obesity connection: A comprehensive overview of biological, physiological and behavioural dimensions

Clinical Obesity, Volume 15, Issue 2, April 2025.
Summary Chronic stress, characterized by increased long‐term exposure to the glucocorticoid hormone cortisol, is increasingly linked to obesity development. Still, various knowledge gaps persist, including on underlying pathophysiological mechanisms. The aim of the current review is to provide the latest insights on the connection between stress and ...
Robin Lengton, Myrte Schoenmakers, Brenda W. J. H. Penninx, Mariëtte R. Boon, Elisabeth F. C. van Rossum   +4 more
wiley   +1 more source

Orofacial pain disorder or trigeminal autonomic cephalalgia? Insights into pathophysiology and implications in medicine and dentistry

Headache: The Journal of Head and Face Pain, EarlyView.
There are some headache disorders known as trigeminal autonomic cephalalgias (TACs). When these “headaches” are localized in the mid‐face region, they are known as “trigeminal autonomic orofacial pains” (TAOPs), and they can mimic other types of face pains including dental pain, which puts the patient at risk of receiving treatments that are incorrect.
Marcela Romero‐Reyes, Simon Akerman
wiley   +1 more source

New perspectives on polycystic ovary syndrome: hypothalamic-sympathetic-adipose tissue interaction

Journal of Ovarian Research
Polycystic Ovary Syndrome (PCOS) is a prevalent endocrine and metabolic disorder among women of reproductive age. Although the traditional mechanistic framework has focused on dysregulation of the hypothalamic-pituitary-ovarian axis (HPOA), emerging ...
Shinan Zhang, Ningxiao Jiang, Guo Liu, Baolin Zhang, Huishu Xu, Yingjiang Xu, Gaofeng Qin, Yanlin Wang, Lei Zhang, Boping Yang, Lei Han   +10 more
doaj   +1 more source

Innovations in Obesity Treatment: Beyond Adipose Tissue Dysfunction

Obesity Reviews, EarlyView.
Obesity drives chronic inflammation, insulin resistance, type 2 diabetes, and cancer development through adipocyte dysfunction. Addressing this multisystemic disorder requires integrated strategies beyond diet and exercise, such as thermogenesis activation via menthol or capsinoids and appetite control through GLP‐1/GIP agonists and neuromodulation to ...
Jesica Martínez‐Godfrey, Irene Pomares‐Bri, Paula de Juan‐Maciá, Mariló Olivares‐Vicente, Enrique Barrajón‐Catalán, Vicente Micol, Enrique Roche, María Herranz‐López   +7 more
wiley   +1 more source

The proportion of neurons exhibiting cytoplasmic Fto-localisation in LHA, PVN and MVN of the rats subjected to 48 h fasting.

, 2013
(LHA; lateral hypothalamic area, PVN; paraventricular nucleus, MVN; medioventral nucleus).
Sinisa F. Djurasevic (410028), Stefan Stamenkovic (410025), Nebojsa Jasnic (410026), Gordana Cvijic (410029), Jelena Djordjevic (410030), Iva Lakic (410027), Predrag Vujovic (410024)   +6 more
core   +1 more source

Microbiome and Metabolomics in Obesity: Advances in Understanding and Interventions Across the Lifespan

Obesity Reviews, EarlyView.
ABSTRACT Obesity arises from intertwined and reciprocal diet‐microbiome‐host pathways that reshape energy balance, insulin sensitivity, and inflammation. This review synthesizes mechanistic links between microbial functions and metabolic control, charts lifestyle‐related lifecourse dynamics from birth to older age, examines how GLP‐1‐based therapies ...
Ioanna Panagiota Kalafati, David Krongauz, Alice Bosco, Antonio Noto, Cristina Piras, Maria Kafyra, Angelica Dessì, Matteo Mauri, Luigi Atzori, Adina Weinberger, Vassilios Fanos, George V. Dedoussis, on behalf of the BETTER4U consortium   +12 more
wiley   +1 more source

Oxytocinergic Cells of the Hypothalamic Paraventricular Nucleus Are Involved in Food Entrainment

Frontiers in Neuroscience, 2020
When food is presented at a specific time of day subjects develop intense locomotor behavior before food presentation, termed food anticipatory activity (FAA). Metabolic and hormonal parameters, as well as neural structures also shift their rhythm according to mealtime. Food-entrained activity rhythms are thought to be driven by a distributed system of
Mario Caba, César Huerta, Enrique Meza, Manuel Hernández, María J. Rovirosa-Hernández   +4 more
openaire   +3 more sources

Metabolic and serotonergic modulation of hypothalamic arcuate nucleus neurones in vitro [PDF]

1. The effects of glucose on the electrophysiological properties of rat hypothalamic arcuate nucleus (ARC) neurones were investigated. Neurones were recorded in 10 mM (hyperglycaemic) and 2 mM (euglycaemic) glucose-containing aCSF.
Saker, Louise
core  

Ovariectomy, but not moderate intermittent hypoxia, promotes respiratory instability and risk of obesity in adult female rats

Experimental Physiology, EarlyView.
Abstract Sleep apnoea (SA) is a prevalent and complex respiratory disorder associated with recurrent interruptions of air flow during sleep. SA causes sleep fragmentation and intermittent hypoxia which leads to numerous negative health consequences.
Marianne Gagnon, Stéphanie Fournier, François Marcouiller, Natalie J. Michael, Vincent Joseph, Richard Kinkead   +5 more
wiley   +1 more source