Results 71 to 80 of about 260,143 (289)

Islamic Counseling to Improve Quality of Parenting Pattern

Konseling Religi: Jurnal Bimbingan Konseling Islam, 2019
So many problems that occur in children and adolescents, one of which is the increased juvenile delinquency. One of the factors of the problem is the low quality of care or parenting.
Ahmad Saifuddin
doaj   +1 more source

Evaluating the Efficacy of an Attachment-Informed Psychotherapeutic Parenting Program for Incarcerated Parents [PDF]

, 2017
An attachment-based, psychotherapeutic parent education course was created for incarcerated mothers and fathers to improve their ability to provide positive parenting and a more stable home environment for their children.
Drzewiecki, Dolly, Kamptner, N. Laura, Rockwood, Nicholas J., Teyber, Faith H.   +3 more
core   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

Molecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute, Júlia Huguet‐Pradell, Jordi Abril‐Fornaguera, Albert Gris‐Oliver, Alex Rialdi, Elisa Fernández‐Martínez, Carla Montironi, Vanessa Del Pozo, Peter Houghton, Laura Zanatto, Agavni Mesropian, Ieva Keraite, Swan Thung, Carolina Armengol, Pau Sancho‐Bru, Ernesto Guccione, Roser Pinyol, Josep M. Llovet   +17 more
wiley   +1 more source

Correlation between parenting styles and social communication in children with hearing impaired

Liaquat Medical Research Journal
This study aimed to find the correlation between parenting style and social communication in children with hearing impairment. In this correlational study Minnesota Social skills checklist for Deaf/ hard of Hearing children and Parenting Style ...
Samia Sharif, Aleena Irum, Hafsa Noreen, Hajra Masood, Hina Sameeullah   +4 more
doaj   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Evaluation of the Ballyfermot Strengthening Families Programme. [PDF]

, 2010
The Strengthening Families Programme (SFP) is an internationally recognised parenting and family skills initiative for high-risk families. It was developed by Dr.
Howley, Derval, Kavanagh, Mick
core  

Support and Services for Parents:A Review of the Literature in Engaging and Supporting Parents [PDF]

, 2007
This literature review aims to draw together existing knowledge on assessing and evaluating parenting interventions. In conducting the literature review, the research team was interested in re-examining the historical policy context to locate the ...
Curran, Joe, Hutton, Linda, MacQueen, Sarah, Whyte, Bill   +3 more
core   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Parenting Styles and the Development of Socio-Emotional Regulation Skills in Preschool Children

Journal of Psychometric Research
The study employed descriptive survey design to investigate the Parenting Styles and the Development of Socio-Emotional Regulation Skills of Preschool Children.
Rahmatallahi Taiye Ojibara
doaj   +1 more source