Results 141 to 150 of about 7,374 (163)

New Insights into Parthanatos as Programmed Cell Death During Murine Cytomegalovirus or Herpes Simplex Virus Type 1 Productive Replication in Diverse Cell Types. [PDF]

Cells
Oh JJ, Xie X, Dix RD.
europepmc   +1 more source

Mechanistic insights into the monotherapy and combination potential of FEN1 inhibition in cancer therapy. [PDF]

Nucleic Acids Res
Rajendra E, Lademann CA, Mason B, Mardin BR, Armstrong L, Peripolli S, Kreis J, Konstantinou T, Pehl U, Bomke J, Scharrelmann S, Perera D, Leuthner B, Pinto MF, Davis OA, Galbiati A, Toste Rêgo A, McWhirter CL, Elinati E, Sala-Hojman A, Lefranc J, Mann SE, Heald RA, Zenke FT, Smith GCM, Robinson HMR, Burgdorf LT.   +26 more
europepmc   +1 more source

ADP-Ribosylation of Cytidine: A Novel Nucleic Acid Modification Reversed by NADAR Hydrolases. [PDF]

Toxins (Basel)
Mikolčević P, Hloušek-Kasun A, Schuller M, Lu Y, Pirović E, Ahel I, Mikoč A.   +6 more
europepmc   +1 more source

PARP1 and PARylation facilitate transcription-coupled DNA repair by stabilizing the CSB-RNAPII complex. [PDF]

Nucleic Acids Res
Robu M, Shah RG, van den Heuvel D, Coulombe Y, Bazin M, van der Woude M, Kragten A, Lans H, Pascal JM, Masson JY, Luijsterburg MS, Shah GM.   +11 more
europepmc   +1 more source

Purification of Recombinant Human PARG and Activity Assays

Methods in Molecular Biology, 2017
The purification of Poly(ADP-ribose) glycohydrolase (PARG) from overexpressing bacteria Escherichia coli is described here to a fast and reproducible one chromatographic step protocol. After cell lysis, GST-PARG-fusion proteins from the crude extract are
Elea Heberle, Françoise Dantzer, Valerie Schreiber   +2 more
exaly   +3 more sources

Selective Loss of PARG Restores PARylation and Counteracts PARP Inhibitor-Mediated Synthetic Lethality

Cancer Cell, 2018
Inhibitors of poly(ADP-ribose) (PAR) polymerase (PARPi) have recently entered the clinic for the treatment of homologous recombination (HR)-deficient cancers.
Ewa Gogola, Wouter W Wiegant, Roebi de Bruijn   +2 more
exaly   +3 more sources

PARG Protein Regulation Roles in Drosophila Longevity Control

International Journal of Molecular Sciences
Aging, marked by a gradual decline in physiological function and heightened vulnerability to age-related diseases, remains a complex biological process with multifaceted regulatory mechanisms.
Guillaume Bordet, Alexei V Tülin, Bordet Guillaume   +2 more
exaly   +2 more sources

Some of the next articles are maybe not open access.

Related searches:

PARG inhibition limits HCC progression and potentiates the efficacy of immune checkpoint therapy

Journal of Hepatology, 2022
Zheng Chen, Qiang Zhou, Shufeng Liu
exaly