Results 111 to 120 of about 6,416 (143)

Genome-wide CRISPR-Cas9 screening identifies CLK1 inhibition as a strategy to restore PARP inhibitor sensitivity via ERCC1 isoform switching. [PDF]

Protein Cell
Liu C, Xu F, Wu Y, Li J, Ni M, Xia S, Chen L, Zhao H, Yu M, Zhou Y, Zhang M, Li J, Wu X, Huang Y, Zhu T, Chen X.   +15 more
europepmc   +1 more source

Bifendate inhibits cell PARthanatos by activating the MEK/ERK pathway. [PDF]

Biochem Biophys Rep
Hu AM, Chen M, Zhu CC, Zhu ZM, Xu XH.
europepmc   +1 more source

Screening the Pandemic Response Box identifies novel ligands of the Staphylococcus aureus protein arginine kinase, McsB. [PDF]

Mol Biol Rep
Chetty R, Delport A, Mthembu S, Veale CGL, Hewer R.   +4 more
europepmc   +1 more source

RECQL4 requires PARP1 for recruitment to DNA damage, and PARG dePARylation facilitates its associated role in end joining. [PDF]

Exp Mol Med
Hussain M, Khadka P, Pekhale K, Kulikowicz T, Gray S, May A, Croteau DL, Bohr VA.   +7 more
europepmc   +1 more source

Synergistic Effect of Ubiquitin-Specific Protease 14 and Poly(ADP-Ribose) Glycohydrolase Co-Inhibition in BRCA1-Mutant, Poly(ADP-Ribose) Polymerase Inhibitor-Resistant Triple-Negative Breast Cancer Cells. [PDF]

Onco Targets Ther
Li P, Zhu X, Qu H, Han Z, Yao X, Wei Y, Li B, Chen H.   +7 more
europepmc   +1 more source

O-GlcNAcylation of the tumor suppressor LATS1 drives mitotic progression via PLK1. [PDF]

J Biol Chem
Meng L, Wang Y, Zhou W, Wu S, Li J.
europepmc   +1 more source

Protocol for synthesizing and purifying short-length poly(ADP)ribose polymer using fast protein liquid chromatography. [PDF]

STAR Protoc
Neeharika S, Hanuman DS, Rajakumara E.
europepmc   +1 more source

A novel radiosensitizer α-sulfoquinovosyl-acylpropanediol (SQAP) inhibits DNA repair pathways and sensitize cells to cancer chemotherapeutic agents. [PDF]

Sci Rep
Maeda J, Sunada S, Fukuhara T, Kato TA.
europepmc   +1 more source

Global remodeling of ADP-ribosylation by PARP1 suppresses influenza A virus infection. [PDF]

Nat Commun
Zhang Z, Uribe I, Davis KA, McPherson RL, Larson GP, Badiee M, Tran V, Ledwith MP, Feltman EM, Yú S, Caì Y, Chang CY, Yang X, Ma Z, Chang P, Kuhn JH, Leung AKL, Mehle A.   +17 more
europepmc   +1 more source

Liquid‒liquid phase separation and poly(ADP‒ribosyl)ation in the context of ultraviolet radiation-induced stress in mammalian cells. [PDF]

Biophys Rev
Mejías D, Seballos V, Lafon-Hughes L.
europepmc   +1 more source