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TIGAR deficiency enhances cardiac resilience through epigenetic programming of Parkin expression. [PDF]
Tang Y +8 more
europepmc +1 more source
Addiction, Volume 121, Issue 9, Page 2575-2576, September 2026.
Julien Cabé, Georges Brousse
wiley +1 more source
SphK1/mitophagy axis in cementocytes drives orthodontic root resorption via mitochondrial transfer to osteoclasts. [PDF]
Wang H +8 more
europepmc +1 more source
Advances in understanding mitophagy's role in lung injury. [PDF]
Du W +6 more
europepmc +1 more source
Research based on serine metabolism indicates mesenchymal stem cells alleviate psoriasis by regulating the PSPH-PINK1-Parkin-NLRP3 pathway in HaCaT. [PDF]
Lin Q +5 more
europepmc +1 more source
Prolonged Photosensitivity Following Exposure to Glyphosate Herbicide
Photodermatology, Photoimmunology &Photomedicine, Volume 42, Issue 5, September 2026.
Jean Ayer +2 more
wiley +1 more source
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No Parkin Zone: Mitophagy without Parkin
Trends in Cell Biology, 2018Mitochondria are essential highly dynamic organelles that provide the necessary energy for a variety of different processes, such as survival, proliferation, and migration. In order to maintain an intact mitochondrial network, cells have developed quality control systems that allow the removal of damaged or superfluous mitochondria by selective ...
Elodie, Villa +2 more
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Parkin and mitochondrial signalling
Cellular Signalling, 2023Aging, toxic chemicals and changes to the cellular environment are sources of oxidative damage to mitochondria which contribute to neurodegenerative conditions including Parkinson's disease. To counteract this, cells have developed signalling mechanisms to identify and remove select proteins and unhealthy mitochondria to maintain homeostasis.
Elizabeth M, Connelly +2 more
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Parkin and Parkinsonʼs disease
Current Opinion in Neurology, 2001Parkin is the causative gene for an autosomal recessive form of Parkinson's disease. The gene was discovered in 1998. The parkin gene is a novel gene containing 12 exons spanning over 1.5 Mb and encodes a protein of 465 amino acids with a molecular mass of approximately 52,000 M(r). Various deletion mutations and point mutations have been discovered in
Y, Mizuno +4 more
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