Results 211 to 220 of about 44,057 (302)

Melatonin Exerts Chondroprotective Effects Against Osteoarthritis by Promoting PI3K/AKT/FoxO3‐Mediated Mitophagy

The Kaohsiung Journal of Medical Sciences, Volume 42, Issue 5, May 2026.
ABSTRACT Osteoarthritis (OA) is a prevalent degenerative joint disease. This study combines bioinformatics analysis with in vivo and in vitro experiments to elucidate the molecular mechanisms through which melatonin (MT) regulates mitophagy to alleviate OA.
Chao Huang, Gang Zhang, Ying‐Kai Ma, Xin‐Nan Ma, Song‐Cen Lv   +4 more
wiley   +1 more source

Proteolytic control of mitochondrial protein translocases

Protein Science, Volume 35, Issue 5, May 2026.
Abstract Mitochondria are essential organelles that drive numerous cellular processes, including energy metabolism, ion homeostasis, and programmed cell death. This functional versatility relies on a highly dynamic proteome whose composition is continuously remodeled to meet changing cellular and environmental demands.
Lara Kroczek, Thomas Langer
wiley   +1 more source

Structural and functional insights into TBC1D17 highlight the importance of the previously uncharacterized Rab‐binding domain

Protein Science, Volume 35, Issue 5, May 2026.
Abstract TBC (Tre2/Bub2/Cdc16) domain‐containing proteins constitute the widespread family of GTPase‐activating proteins (GAPs). They interact with the Rab superfamily of small GTPases, stimulate GTP hydrolysis, and regulate vesicle trafficking. TBC1D17, involved in Shiga toxin trafficking, autophagy and glucose metabolism regulation, constitutes an ...
Dominika Nielipińska, Marta Orlikowska, Maciej Nielipiński, Bartosz Sekuła, Katarzyna M. Błażewska, Edyta Gendaszewska‐Darmach, Agnieszka J. Pietrzyk‐Brzezińska   +6 more
wiley   +1 more source

Mitochondrial Homeostasis in Diabetic Cardiomyopathy: From Dysfunction to Therapeutic Strategies. [PDF]

Antioxidants (Basel)
Huang Y, Zou W, Jiang X, Cheng J, Zheng J.   +4 more
europepmc   +1 more source

Supplementary material from "Phosphorylation of Parkin at serine 65 is essential for its activation in vivo"

, 2018
Thomas G. McWilliams, Erica Barini, Risto Pohjolan-Pirhonen, Simon P. Brooks, François Singh, Sophie Burel, Kristin Balk, Atul Kumar, Lambert Montava‐Garriga, Alan R. Prescott, Sidi Mohamed Hassoun, François Mouton‐Liger, Graeme Ball, Rachel Hills, Axel Knebel, Ayşe Ulusoy, Donato A. Di Monte, J. Tamjar, Odetta Antico, Kyle Fears, Laura Smith, Riccardo Brambilla, Eino Palin, Miko Valori, Johanna Eerola‐Rautio, Pentti J. Tienari, Olga Corti, Stephen B. Dunnett, Ian G. Ganley, Anu Suomalainen, Miratul M. K. Muqit   +30 more
openalex   +1 more source

Quality control of protein import into mammalian mitochondria

Protein Science, Volume 35, Issue 5, May 2026.
Abstract Mitochondrial function depends on the continuous import of hundreds of nuclear‐encoded proteins. Targeting and translocation of mitochondrial proteins is a multistep process that is inherently vulnerable to defects in cytosolic quality control systems as well as perturbations in mitochondrial protein import machinery and organelle function ...
Madeleine Goldstein, Laurie Lee‐Glover, Hilla Weidberg   +2 more
wiley   +1 more source

Parkin-ACSL4 axis in ferroptosis regulation: a narrative review on therapeutic insights from exercise in aging cardiomyocytes. [PDF]

NPJ Metab Health Dis
Kordi N, Bagherzadeh-Rahmani B, KheirAndish R, Rezaali R, Stockwell BR.   +4 more
europepmc   +1 more source

Enhancing soil health through no‐till, cover crops, and compost: A 5‐year field study

Soil Science Society of America Journal, Volume 90, Issue 3, May/June 2026.
Abstract The capacity of soil management systems to conserve and promote soil health is crucial for its sustainability. While the effects of individual soil management practices on soil health receive considerable attention, their combined effects remain understudied. This paper presents the results of a 5‐year field experiment designed to evaluate the
Daniel Růžička, Helena Dvořáčková, Jana Vavříková, Karel Klem, Jaroslav Záhora, Sneha Patra   +5 more
wiley   +1 more source

<i>Listeria monocytogenes</i> invasion in goat brain tissues: mechanisms of blood-brain barrier disruption and regulation of apoptosis and autophagy. [PDF]

Front Microbiol
Hu Y, Liu L, Zheng W, Liu B, Ding S, Shi S, Wu Y, Cao Y, Liu J, Zhou X, Huang X.   +10 more
europepmc   +1 more source

Performance of five common soil moisture sensors using default calibration equations in low‐salinity conditions

Vadose Zone Journal, Volume 25, Issue 3, May/June 2026.
Abstract Soil moisture monitoring plays a critical role in water resource management, hydrological modeling, and climate studies, making sensor accuracy and reliability increasingly important. This study evaluates the performance of five soil moisture sensors—the CS655, HydraProbe, TDR‐315N, TEROS 12, and ThetaProbe—using their default calibrations ...
Seyed Ali Azizi, Briana M. Wyatt, Andres Patrignani, Tyson E. Ochsner, Michael Cosh   +4 more
wiley   +1 more source