Results 71 to 80 of about 472,711 (314)
Circadian rest-activity rhythms predict cognitive function in early Parkinson's disease independently of sleep [PDF]
, 2018 BACKGROUND: Cognitive impairment is a common and debilitating symptom of Parkinson's disease (PD), and its etiology is likely multifactorial. One candidate mechanism is circadian disruption. Although there is evidence of circadian abnormalities in PD, no
Cronin-Golomb, Alice +4 more
core +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Neurodegeneration with brain iron accumulation (NBIA) comprises a genetically and clinically heterogeneous group of rare neurological disorders characterized particularly by iron accumulation in the basal ganglia. To date, 15 genes have been associated with NBIA.
Seda Susgun +95 more
wiley +1 more source
Applied Bionics and Biomechanics, 2022 Dementia in Parkinson’s disease (PD) has become a major factor affecting the quality of life of patients with Parkinson’s disease. Early detection and timely prevention can delay the progression of dementia, improve the quality of life of patients, and ...
Qianqian Niu, Weijie Xu
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective This study aims to identify both fluid and neuroimaging biomarkers for CSF1R‐RD that can inform the optimal timing of treatment administration to maximize therapeutic benefit, while also providing sensitive quantitative measurements to monitor disease progression.
Tomasz Chmiela +13 more
wiley +1 more source
COGNITIVE IMPAIRMENT AND DEMENTIA IN PARKINSON'S DISEASE
Актуальные проблемы теоретической и клинической медициныCognitive impairment is one of the most frequent and disabling non-motor manifestations of Parkinson's disease. It significantly reduces patients' quality of life, increases caregiver burden, and contributes to loss of independence.
A. Kondybayeva +6 more
doaj +1 more source
Acta Neuropathologica Communications, 2019 Synucleinopathies [Parkinson’s disease with or without dementia, dementia with Lewy bodies and multiple system atrophy] are neurodegenerative diseases that are defined by the presence of filamentous α-synuclein inclusions.
Therése Klingstedt +5 more
doaj +1 more source
Neuropsychiatric disturbances in atypical Parkinsonian disorders [PDF]
, 2018 Multiple system atrophy (MSA), progressive supranuclear palsy (PSP), and corticobasal degeneration (CBD) are the most common atypical parkinsonisms. These disorders are characterized by varying combinations of autonomic, cerebellar and pyramidal system ...
Belvisi, Daniele +6 more
core +1 more source
An Out‐of‐Place Etiology: Recognizing FMR1 Premutation in the Memory Clinic
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT The FMR1 gene premutation (55–200 CGG repeats) is usually associated with a wide range of symptoms and phenotypes within the Fragile X‐tremor/ataxia syndrome (FXTAS), but may also manifest as predominant or isolated cognitive decline. We describe three male patients referred for progressive cognitive impairment and behavioral changes. Standard
Guido Greco +7 more
wiley +1 more source
Frontiers in NeurologyObjectivesThis meta-analysis investigated the relationship between herpes zoster and the risk of dementia or Parkinson’s disease by analyzing published clinical studies.MethodsWe systematically searched PubMed, Cochrane, Embase, and Web of Science Core ...
Yanfeng Zhang +3 more
doaj +1 more source
Prediction of Parkinson’s Disease Depression Using LIME-Based Stacking Ensemble Model
Mathematics, 2023 Depression symptoms are comparable to Parkinson’s disease symptoms, including attention deficit, fatigue, and sleep disruption, as well as symptoms of dementia such as apathy.
Hung Viet Nguyen, Haewon Byeon
doaj +1 more source