Results 31 to 40 of about 442,406 (307)

Cognitive behaviour therapy-trained staff’s views on professional accreditation [PDF]

open access: yes, 2017
Many cognitive behaviour therapy (CBT) trained mental health professionals seek non-mandatory accreditation with the British Association for Behavioural and Cognitive Psychotherapies (BABCP), despite self-regulation of talking therapies being a divisive ...
Marks, Dougie, Parkinson, Ben
core   +4 more sources

Microglial Phagocytosis and Its Regulation: A Therapeutic Target in Parkinson’s Disease?

open access: yesFrontiers in Molecular Neuroscience, 2018
The role of phagocytosis in the neuroprotective function of microglia has been appreciated for a long time, but only more recently a dysregulation of this process has been recognized in Parkinson’s disease (PD).
Elzbieta Janda, Laura Boi, Anna R. Carta
doaj   +1 more source

Opposition diagrams for automorphisms of large spherical buildings [PDF]

open access: yes, 2018
Let $\theta$ be an automorphism of a thick irreducible spherical building $\Delta$ of rank at least $3$ with no Fano plane residues. We prove that if there exist both type $J_1$ and $J_2$ simplices of $\Delta$ mapped onto opposite simplices by $\theta ...
Parkinson, J., Van Maldeghem, H.
core   +3 more sources

Parkinson's Disease and Parkinsonism: Neuropathology [PDF]

open access: yesCold Spring Harbor Perspectives in Medicine, 2012
Parkinsonism, the clinical term for a disorder with prominent bradykinesia and variable associated extrapyramidal signs and symptoms, is accompanied by degeneration of the nigrostriatal dopaminergic system, with neuronal loss and reactive gliosis in the substantia nigra found at autopsy.
openaire   +2 more sources

A Comparative Study of Cerebral Oxygenation During Exercise in Hemodialysis and Peritoneal Dialysis Patients

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Cognitive impairment and exercise intolerance are common in dialysis patients. Cerebral perfusion and oxygenation play a major role in both cognitive function and exercise execution; HD session per se aggravates cerebral ischemia in this population. This study aimed to compare cerebral oxygenation and perfusion at rest and in mild
Marieta P. Theodorakopoulou   +10 more
wiley   +1 more source

Transcranial alternating current stimulation improves quality of life in Parkinson’s disease: study protocol for a randomized, double-blind, controlled trial

open access: yesTrials
Background The neural cells in the brains of patients with Parkinson’s disease (PWP) display aberrant synchronized oscillatory activity within the beta frequency range.
Hong-yu Zhang   +16 more
doaj   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Handwriting analysis for diagnosis and prognosis of Parkinson’s disease [PDF]

open access: yes, 2010
At present, there are no quantitative, objective methods for diagnosing the Parkinson disease. Existing methods of quantitative analysis by myograms suffer by inaccuracy and patient strain; electronic tablet analysis is limited to the visible drawing ...
Brause, Rüdiger W.   +2 more
core  

Intravitreal Anti-VEGF Drugs and Signals of Dementia and Parkinson-Like Events: Analysis of the VigiBase Database of Spontaneous Reports [PDF]

open access: yes, 2020
Introduction: Since vascular endothelial growth factor (VEGF) regulates several aspects of the central nervous system, particularly in dopaminergic neurons, VEGF inhibitors may be linked to Parkinson-like events and dementia, or variants of these ...
Avery   +30 more
core   +4 more sources

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

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