Inflammation and immune dysfunction in Parkinson disease
Nature Reviews Immunology, 2022 Parkinson disease (PD) is a progressive neurodegenerative disease that affects peripheral organs as well as the central nervous system and involves a fundamental role of neuroinflammation in its pathophysiology. Neurohistological and neuroimaging studies
Malú Gámez Tansey +2 more
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No sex differences in use of dopaminergic medication in early Parkinson disease in the US and Canada - baseline findings of a multicenter trial. [PDF]
PLoS ONE, 2014 Sex differences in Parkinson disease clinical features have been reported, but few studies have examined sex influences on use of dopaminergic medication in early Parkinson disease.
Chizoba C Umeh +10 more
doaj +6 more sources
Parkinson disease-associated cognitive impairment
Nature Reviews Disease Primers, 2021 Dag Aarsland +2 more
exaly +3 more sources
Non-motor features of Parkinson disease
Nature Reviews Neuroscience, 2017 Anthony H V Schapira +1 more
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Cognitive decline in Parkinson disease
Nature Reviews Neurology, 2017 Dag Aarsland +2 more
exaly +2 more sources
Is restless legs syndrome in Parkinson disease patients associated with any specific factor? [PDF]
Arquivos de Neuro-Psiquiatria, 2021 Background: Restless legs syndrome or Willis-Ekbom disease is a disorder characterized by unpleasant sensations associated with the need to mobilize the lower limbs.
Manoel Alves SOBREIRA-NETO +7 more
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Stability of MDS-UPDRS Motor Subtypes Over Three Years in Early Parkinson's Disease
Frontiers in Neurology, 2021 Background: Various classifications have been proposed to subtype Parkinson's disease (PD) based on their motor phenotypes. However, the stability of these subtypes has not been properly evaluated.Objective: The goal of this study was to understand the ...
Abhijeet K. Kohat +33 more
doaj +1 more source
Discriminating α-synuclein strains in Parkinson’s disease and multiple system atrophy
Nature, 2020 Mohammad Shahnawaz +2 more
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Slow wave activity across sleep-night could predict levodopa-induced dyskinesia
Scientific Reports, 2023 A disruption in the slow wave activity (SWA) mediated synaptic downscaling process features Parkinson's disease (PD) patients presenting levodopa-induced dyskinesia (LID).
Ninfa Amato +5 more
doaj +1 more source
Circular RNAs in the human brain are tailored to neuron identity and neuropsychiatric disease
Nature Communications, 2023 Little is known about circular RNAs (circRNAs) in specific brain cells and human neuropsychiatric disease. Here, we systematically identify over 11,039 circRNAs expressed in vulnerable dopamine and pyramidal neurons laser-captured from 190 human brains ...
Xianjun Dong +11 more
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