Results 1 to 10 of about 273,958 (281)
No sex differences in use of dopaminergic medication in early Parkinson disease in the US and Canada - baseline findings of a multicenter trial. [PDF]
PLoS ONE, 2014 Sex differences in Parkinson disease clinical features have been reported, but few studies have examined sex influences on use of dopaminergic medication in early Parkinson disease.
Chizoba C Umeh +10 more
doaj +11 more sources
Role of Mitochondria in Parkinson Disease [PDF]
, 1999 The cause of the selective degeneration of nigrostriatal neurons in Parkinson disease (PD) has remained largely unknown. Exceptions include rare missense mutations in the alpha-synuclein gene on chromosome 4, a potentially pathogenic mutation affecting ...
Siegfried Kösel +4 more
openalex +3 more sources
Measuring the Burden of Hospitalization in Patients with Parkinson´s Disease in Spain. [PDF]
PLoS ONE, 2016 IntroductionThis epidemiological survey estimates the hospitalization burden related to Parkinson´s Disease in Spain.MethodsThis observational retrospective survey was performed by reviewing data from the National Surveillance System for Hospital Data ...
Ruth Gil-Prieto +5 more
doaj +5 more sources
The Lancet, 2021 Parkinson's disease is a recognisable clinical syndrome with a range of causes and clinical presentations. Parkinson's disease represents a fast-growing neurodegenerative condition; the rising prevalence worldwide resembles the many characteristics typically observed during a pandemic, except for an infectious cause.
Bloem, B.R., Okun, M.S., Klein, C.
openaire +2 more sources
Stability of MDS-UPDRS Motor Subtypes Over Three Years in Early Parkinson's Disease
Frontiers in Neurology, 2021 Background: Various classifications have been proposed to subtype Parkinson's disease (PD) based on their motor phenotypes. However, the stability of these subtypes has not been properly evaluated.Objective: The goal of this study was to understand the ...
Abhijeet K. Kohat +33 more
doaj +1 more source
Is restless legs syndrome in Parkinson disease patients associated with any specific factor? [PDF]
Arquivos de Neuro-Psiquiatria, 2021 Background: Restless legs syndrome or Willis-Ekbom disease is a disorder characterized by unpleasant sensations associated with the need to mobilize the lower limbs.
Manoel Alves SOBREIRA-NETO +7 more
doaj +1 more source
Slow wave activity across sleep-night could predict levodopa-induced dyskinesia
Scientific Reports, 2023 A disruption in the slow wave activity (SWA) mediated synaptic downscaling process features Parkinson's disease (PD) patients presenting levodopa-induced dyskinesia (LID).
Ninfa Amato +5 more
doaj +1 more source
Circular RNAs in the human brain are tailored to neuron identity and neuropsychiatric disease
Nature Communications, 2023 Little is known about circular RNAs (circRNAs) in specific brain cells and human neuropsychiatric disease. Here, we systematically identify over 11,039 circRNAs expressed in vulnerable dopamine and pyramidal neurons laser-captured from 190 human brains ...
Xianjun Dong +11 more
doaj +1 more source
Patient-Centric Care for Parkinson's Disease: From Hospital to the Community
Frontiers in Neurology, 2020 Parkinson's disease (PD) is a chronic neurodegenerative disease with complex motor and non-motor symptoms often leading to significant caregiver burden.
Yin Minn Aye +27 more
doaj +1 more source
The Lancet, 2004 Parkinson's disease is the most common serious movement disorder in the world, affecting about 1% of adults older than 60 years. The disease is attributed to selective loss of neurons in the substantia nigra, and its cause is enigmatic in most individuals.
Samii, Ali +2 more
openaire +3 more sources