Results 1 to 10 of about 151,391 (216)

Exposure to disulfiram and incidence of parkinsonism [PDF]

Journal of Occupational Medicine and Toxicology
Background Case reports implicate disulfiram treatment in causing parkinsonism, but these observations lack epidemiological confirmation. Aim of the present study was to estimate the risk of incident parkinsonism associated with disulfiram dispensing in ...
Angelo d’Errico, Elena Strippoli, Samuel M. Goldman, Paul D. Blanc   +3 more
doaj   +2 more sources

Drug-induced parkinsonism in a patient with DiGeorge syndrome: a case report [PDF]

Frontiers in Neuroscience
DiGeorge syndrome, also referred as 22q11.2 deletion syndrome is a multisystem disorder associated with an increased risk of early-onset parkinsonism.
Clancy Cerejo, Nicolas De Cleene, Gerald Walser, Atbin Djamshidian, Klaus Seppi, Beatrice Heim   +5 more
doaj   +2 more sources

Challenging Diagnosis of Fahr's Disease Mimicking Parkinson's Disease: A Case Report [PDF]

Clinical Case Reports
Patients presenting with parkinsonism symptoms such as severe bradykinesia and significant hypophonia, along with an atypical clinical course, should be evaluated for secondary parkinsonism syndromes and other causes of parkinsonism.
Erfan Sanaei, Reza Bidaki, Mohammad Pashmchi, Hamid Jalalifard   +3 more
doaj   +2 more sources

Spatial discrimination in patients with MSA, PSP, DIP, and VP with pain [PDF]

Scientific Reports
Pain is common in Parkinson’s disease and frequently observed in other diseases involving parkinsonism. Abnormal scaling function in PD has been reportedly associated with pain, but the role of this function in pain in other parkinsonism-related diseases
Min Seung Kim, Jaeho Kim, Suk Yun Kang
doaj   +2 more sources

Viral Parkinsonism: An underdiagnosed neurological complication of Dengue virus infection

PLoS Neglected Tropical Diseases, 2022
Dengue virus (DENV) is a flavivirus that is a significant cause of human disease costing billions of dollars per year in medical and mosquito control costs. It is estimated that up to 20% of DENV infections affect the brain.
Hannah K. Hopkins, Elizabeth M. Traverse, Kelli L. Barr   +2 more
doaj   +2 more sources

Inhibition of discoidin domain receptor (DDR)-1 with nilotinib alters CSF miRNAs and is associated with reduced inflammation and vascular fibrosis in Alzheimer’s disease

Journal of Neuroinflammation, 2023
Discoidin Domain Receptor (DDR)-1 is activated by collagen. Nilotinib is a tyrosine kinase inhibitor that is FDA-approved for leukemia and potently inhibits DDR-1.
Max Stevenson, Rency Varghese, Michaeline L. Hebron, Xiaoguang Liu, Nick Ratliff, Amelia Smith, R. Scott Turner, Charbel Moussa   +7 more
doaj   +1 more source

Progress on diagnosis and treatment of functional parkinsonism

Chinese Journal of Contemporary Neurology and Neurosurgery, 2023
Functional parkinsonism (FP) is a disorder caused by psychological factors rather than neurodegeneration. Functional parkinsonism has a great influence on patients' quality of life and daily function. However, due to overlapping with some of the symptoms
HUANG Pei, WANG Gang
doaj   +1 more source

Safety, target engagement, and biomarker effects of bosutinib in dementia with Lewy bodies

Alzheimer’s & Dementia: Translational Research & Clinical Interventions, 2022
Introduction Bosutinib, a dual Abelson/Src inhibitor, was investigated in individuals with dementia with Lewy bodies (DLB). Methods A single site, randomized, double‐blind, placebo‐controlled study of the effects of oral bosutinib, 100 mg once daily for ...
Fernando L. Pagan, Yasar Torres‐Yaghi, Michaeline L. Hebron, Barbara Wilmarth, R. Scott Turner, Sara Matar, Dalila Ferrante, Jaeil Ahn, Charbel Moussa   +8 more
doaj   +1 more source

Tumoral parkinsonism—Parkinsonism secondary to brain tumors, paraneoplastic syndromes, intracranial malformations, or oncological intervention, and the effect of dopaminergic treatment

Brain and Behavior, 2023
Introduction Secondary tumoral parkinsonism is a rare phenomenon that develops as a direct or indirect result of brain neoplasms or related conditions.
Gustav Cedergren Weber, Jonathan Timpka, Anna Rydelius, Johan Bengzon, Per Odin   +4 more
doaj   +1 more source

New Perspective on Parkinsonism in Frontotemporal Lobar Degeneration [PDF]

Journal of Movement Disorders, 2013
Frontotemporal dementia (FTD) is the second most common type of presenile dementia. Three clinical prototypes have been defined; behavioral variant FTD, semantic dementia, and progressive nonfluent aphasia.
Hee Kyung Park, Sun J. Chung
doaj   +1 more source