Results 11 to 20 of about 61,853 (265)

Tumoral parkinsonism—Parkinsonism secondary to brain tumors, paraneoplastic syndromes, intracranial malformations, or oncological intervention, and the effect of dopaminergic treatment

Brain and Behavior, 2023
Introduction Secondary tumoral parkinsonism is a rare phenomenon that develops as a direct or indirect result of brain neoplasms or related conditions.
Gustav Cedergren Weber, Jonathan Timpka, Anna Rydelius, Johan Bengzon, Per Odin   +4 more
doaj   +1 more source

Tyrosine kinase inhibition increases functional parkin‐Beclin‐1 interaction and enhances amyloid clearance and cognitive performance

EMBO Molecular Medicine, 2013
Tyrosine kinase inhibitors (TKIs) are effective therapies for leukaemia. Alzheimer is a neurodegenerative disease characterized by accumulation of β‐amyloid (plaques) and hyper‐phosphorylated Tau (tangles).
Irina Lonskaya, Michaeline L. Hebron, Nicole M. Desforges, Alexander Franjie, Charbel E.‐H. Moussa   +4 more
doaj   +1 more source

New Perspective on Parkinsonism in Frontotemporal Lobar Degeneration [PDF]

Journal of Movement Disorders, 2013
Frontotemporal dementia (FTD) is the second most common type of presenile dementia. Three clinical prototypes have been defined; behavioral variant FTD, semantic dementia, and progressive nonfluent aphasia.
Hee Kyung Park, Sun J. Chung
doaj   +1 more source

X-linked Dystonia-Parkinsonism patient cells exhibit altered signaling via nuclear factor-kappa B

Neurobiology of Disease, 2017
X-linked Dystonia-Parkinsonism (XDP) is a progressive neurodegenerative disease involving the loss of medium spiny neurons within the striatum. An XDP-specific haplotype has been identified, consisting of seven sequence variants which cluster around the ...
Christine A. Vaine, David Shin, Christina Liu, William T. Hendriks, Jyotsna Dhakal, Kyle Shin, Nutan Sharma, D. Cristopher Bragg   +7 more
doaj   +1 more source

Altered resting state brain metabolic connectivity in dementia with Lewy bodies

Frontiers in Neurology, 2022
Although dementia with Lewy bodies (DLB) have Parkinsonism in common with Parkinson's disease (PD) or PD dementia (PDD), they have different neuropathologies that underlie Parkinsonism.
Euna Choi, Ji Won Han, Seung Wan Suh, Jong Bin Bae, Ji Hyun Han, Subin Lee, Sang Eun Kim, Sang Eun Kim, Sang Eun Kim, Ki Woong Kim, Ki Woong Kim, Ki Woong Kim   +11 more
doaj   +1 more source

The Current State of Parkinsonism in West Africa: A Systematic Review

Parkinson's Disease, 2021
Parkinsonism is one of the most common neurodegenerative diseases among the elderly. Africa is experiencing an increasing burden of age-related conditions including parkinsonism.
Jude T. Quarshie, Esther N. Mensah, Osbourne Quaye, Anastasia R. Aikins   +3 more
doaj   +1 more source

Parkinson’s Disease and Parkinsonism

The Journal of Turkish Family Physician, 2022
Parkinson’s disease (PD), or paralysis agitans is a common neurodegenerative and heterogeneous disorder. Parkinson’s symptoms include bradykinesia, rigidity and tremor. PD is pathologically characterized by the loss of dopaminergic neurons of the substantia nigra. Treatment involves pharmacologic and nonpharmacologic approaches.
Tuba Erdoğan Soyukibar, Dilaver Kaya
openaire   +1 more source

Burden of Parkinsonism and Parkinson’s Disease on Health Service Use and Outcomes in Latin America

Journal of Parkinson’s Disease, 2023
Background: Little is known about the burden of parkinsonism and Parkinson’s disease (PD) in Latin America. Better understanding of health service use and clinical outcomes in PD is needed to improve its prognosis.
Dani J. Kim, Ana M. Rodriguez-Salgado, Juan J. Llibre-Rodriguez, Isaac Acosta, Ana Luisa Sosa, Daisy Acosta, Ivonne Z. Jimenez-Velasquez, Mariella Guerra, Aquiles Salas, Christine Jeyachandran, Ricardo López-Contreras, Heike Hesse, Caroline Tanner, Jorge J. Llibre-Guerra, Matthew Prina   +14 more
doaj   +1 more source

Study on drug-induced parkinsonism and its clinical patterns in Eastern Indian population

APIK Journal of Internal Medicine, 2023
Background: Drug-induced parkinsonism (DIP) is important as it is reversible if identified and treated early. We present herewith various clinical patterns and drugs commonly causing DIP.
Praveen Kumar Yadav
doaj   +1 more source

Parkinson's Disease and Parkinsonism: Neuropathology [PDF]

Cold Spring Harbor Perspectives in Medicine, 2012
Parkinsonism, the clinical term for a disorder with prominent bradykinesia and variable associated extrapyramidal signs and symptoms, is accompanied by degeneration of the nigrostriatal dopaminergic system, with neuronal loss and reactive gliosis in the substantia nigra found at autopsy.
openaire   +2 more sources