Parkinson's disease biomarkers: perspective from the NINDS Parkinson's Disease Biomarkers Program [PDF]
Biomarkers for Parkinson's disease (PD) diagnosis, prognostication and clinical trial cohort selection are an urgent need. While many promising markers have been discovered through the National Institute of Neurological Disorders and Stroke Parkinson's ...
Albin, Roger+25 more
core +1 more source
Evaluation of Brain SPECT with 99mTc-TRODAT-1 in the Differential Diagnosis of Parkinsonism
Introduction. Brain SPECT with 99mTc-TRODAT-1 (SPECT-TRODAT) may be a useful tool in the differential diagnosis of Parkinsonism. Objective. To compare results of SPECT-TRODAT with clinical findings in patients with Parkinsonism. Methods. We evaluated 153
Giorgio Fabiani+4 more
doaj +1 more source
Neuropsychiatric disturbances in atypical Parkinsonian disorders [PDF]
Multiple system atrophy (MSA), progressive supranuclear palsy (PSP), and corticobasal degeneration (CBD) are the most common atypical parkinsonisms. These disorders are characterized by varying combinations of autonomic, cerebellar and pyramidal system ...
Belvisi, Daniele+6 more
core +1 more source
Terguride stimulates locomotor activity at 2 months but not 10 months after 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine treatment of common marmosets [PDF]
The mixed dopamine (DA) agonist/antagonist terguride acts as a DA antagonist on normosensitive receptors but shows DA agonistic properties at supersensitive DA receptors.
Horowski, R.+6 more
core +1 more source
Infectious Etiologies of Parkinsonism: Pathomechanisms and Clinical Implications
Extensive research in recent decades has expanded our insights into the pathogenesis of Parkinson's disease (PD), though the underlying cause remains incompletely understood.
Nattakarn Limphaibool+4 more
semanticscholar +1 more source
Total daily physical activity, brain pathologies, and parkinsonism in older adults.
ObjectiveWe examined the association of physical activity, postmortem brain pathologies, and parkinsonism proximate to death in older adults.MethodsWe studied the brains of 447 older decedents participating in a clinical-autopsy cohort study. We deployed
Shahram Oveisgharan+6 more
doaj +1 more source
Case Report: Progressive Asymmetric Parkinsonism Secondary to CADASIL Without Dementia
Parkinsonism is a rare phenotype of cerebral autosomal dominant arteriopathy with subcortical infarction and leukoencephalopathy (CADASIL), all of which involve cognitive decline. Normal cognition has not been reported in previous disease studies.
Weihang Guo+23 more
doaj +1 more source
Drug-induced parkinsonism: what should a psychiatrist know?
Drug-induced parkinsonism is the main cause of secondary parkinsonism in the world. Antipsychotics, antidepressants, and mood stabilizers are the most common drugs implicated in the parkinsonism.
Santiago Vásquez-Builes+4 more
doaj +1 more source
Palliative care and Parkinson's disease : meeting summary and recommendations for clinical research [PDF]
Introduction: Palliative care is an approach to caring for patients and families affected by serious illnesses that focuses on the relief of suffering through the management of medical symptoms, psychosocial issues, advance care planning and spiritual ...
Bekelman, David+17 more
core +1 more source
Neuron-specific enolase in the blood serum as a diagnostic marker of Parkinsonism
In the article there were presented data about the received results of immune-enzyme analysis of neuron-specific enolase among patients with Parkinsonism (52) in comparison with control group of patients with discirculatory encephalopathy without ...
F. F. Gashilova, N. G. Zhukova
doaj +1 more source