Results 91 to 100 of about 15,613 (254)

Induction of Prostaglandin Release from Macrophages by Bacterial Endotoxin [PDF]

, 2017
This review summarizes the role of the monocytic responses to lipopolysaccharide as it relates to periodontal disease severity. Data are presented which illustrate that the levels of prostaglandin E2 (PGE2) secreted by systemic peripheral blood monocytes
Offenbacher, S., Salvi, G. E.
core  

Long-term safety and efficacy of eculizumab in generalized myasthenia gravis [PDF]

, 2019
Introduction: Eculizumab is effective and well tolerated in patients with antiacetylcholine receptor antibody-positive refractory generalized myasthenia gravis (gMG; REGAIN; NCT01997229). We report an interim analysis of an open-label extension of REGAIN,
Andersen, Henning, Barohn, Richard J, Benatar, Michael, Burns, Ted M, Casasnovas, Carlos, De Bleecker, Jan, Fujita, Kenji P, Howard, James F, Jr., Illa, Isabel, Jacob, Saiju, Kissel, John T, Mantegazza, Renato, Muppidi, Srikanth, Murai, Hiroyuki, Nowak, Richard J, O'Brien, Fanny L, Utsugisawa, Kimiaki, Vissing, John, Vu, Tuan H, Wang, Jing Jing   +19 more
core   +2 more sources

Long-term outcome of a randomized controlled study in patients with newly diagnosed severe aplastic anemia treated with antithymocyte globulin and cyclosporine, with or without granulocyte colony-stimulating factor: a Severe Aplastic Anemia Working Party Trial from the European Group of Blood and Marrow Transplantation

Haematologica, 2020
This follow-up study of a randomized, prospective trial included 192 patients with newly diagnosed severe aplastic anemia receiving antithymoglobulin and cyclosporine, with or without granulocyte colony-stimulating factor (G-CSF).
André Tichelli, Régis Peffault de Latour, Jakob Passweg, Cora Knol-Bout, Gérard Socié, Judith Marsh, Hubert Schrezenmeier, Britta Höchsmann, Andrea Bacigalupo, Sujith Samarasinghe, Alicia Rovó, Austin Kulasekararaj, Alexander Röth, Dirk-Jan Eikema, Paul Bosman, Peter Bader, Antonio Risitano, Carlo Dufour   +17 more
doaj   +1 more source

Hematological response in patients with paroxysmal nocturnal hemoglobinuria treated with C5-inhibitor

Онкогематология
Background. Paroxysmal nocturnal hemoglobinuria is a rare clonal disease of the hematopoietic system, with the key manifestations of hemolytic anemia, a high thrombosis rate, and bone marrow failure.
V. D. Latyshev, Z. T. Fidarova, R. V. Ponomarev, N. V. Tsvetaeva, E. A. Mikhaylova, E. A. Lukina, E. N. Parovichnikova   +6 more
doaj   +1 more source

Popliteal artery thrombosis as a rare complication of paroxysmal nocturnal hemoglobinuria (PNH)

, 2021
Kiran Bhusal, Prashiddha B. Kadel, Khagendra P. Bhandari, Shova Aryal, Nitin Gyawali, Ashok Kushwaha, Kajan Raj Shrestha, Anjan Shrestha   +7 more
openalex   +1 more source

Population Pharmacokinetic and Pharmacokinetic/Pharmacodynamic Analyses of Pegcetacoplan in Patients with Paroxysmal Nocturnal Hemoglobinuria

Drugs in R&D
Background and Objective Paroxysmal nocturnal hemoglobinuria is a rare blood disorder characterized by life-threatening hemolysis and thrombosis. Complement C5 inhibitor therapy improves symptoms and life prognosis; however, it can result in insufficient
Ryan L. Crass, Brandon Smith, Sven Adriaens, Sunny Chapel, Grant Langdon   +4 more
doaj   +1 more source

FLAER Based Paroxysmal Nocturnal Hemoglobinuria Clone Detection in Patients of Aplastic Anemia: Single Centre Experience from a Developing Country

, 2022
Zohra Farooq, Ghassan Umair Shamshad, Mehreen Ali Khan, Muhammad Nadeem Yousaf, Sobia Umar   +4 more
openalex   +1 more source

Function of Soluble CD14 in Serum from Patients with Septic Shock [PDF]

, 2017
Soluble CD14 (sCD14) mediates lipopolysaccharide (LPS) activation of epithelial cells in vitro and may thereby be harmful in sepsis.sCD14 function was analyzed in sera from 62 patients with septic shock and compared with data from appropriate controls ...
Landmann, Regine, Reber, Anne Marie, Sansano, Sebastiano, Zimmerli, Werner   +3 more
core  

Liver transplantation for the Budd-Chiari syndrome [PDF]

, 1990
A retrospective study was performed that analyzed 23 patients who had an orthotopic liver transplantation for the Budd-Chiari syndrome with end-stage liver disease. Patient follow-up was as long as 14 years.
Gordon, RD, Halff, G, Starzl, TE, Todo, S, Tzakis, AG   +4 more
core   +2 more sources

Paroxysmal Nocturnal Hemoglobinuria

Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2008
Paroxysmal Nocturnal Hemoglobinuria (PNH) literally means to have episodes of hemoglobin in the urine during the night. It is a Coomb's negative rare hemolytic disorder characterized by non-malignant clonal expansion of haemopoietic stem cells due to acquired genetic mutations.
Asad, Mehmood, Muhammad Ashraf, Sharif, Badar, Murtaza   +2 more
openaire   +3 more sources