Results 61 to 70 of about 96,094 (164)

PARP-1 is a transcriptional rheostat of metabolic and bivalent genes during development

Life Science Alliance
PARP-1 fine-tunes gene expression to control energy balance and development by selectively repressing and activating critical genes for developmental progression. PARP-1 participates in various cellular processes, including gene regulation. In Drosophila
Gbolahan Bamgbose, Alexei Tulin
doaj   +1 more source

The clinical significance of serum PARP-1 protein high expression in gastric cancer

Zhongguo aizheng zazhi, 2015
Background and purpose: PARP-1 is closely related to malignant tumors. This study aimed to explore the clinical significance of serum level of PARP-1 protein in onset and progression of gastric cancer.
王　睿, 王　岚, 黎明新
doaj  

Efficacy and safety of PARP inhibitor maintenance therapy in elderly ovarian cancer patients: a real-world single-center retrospective cohort study. [PDF]

Front Oncol
Lu J, Song X, Zhang C, Zhu Y, Yang H, Li Y.   +5 more
europepmc   +1 more source

SLFN11 expression as a marker of small cell lung cancer vulnerability to combined PARP inhibitors and immune checkpoint inhibitors during maintenance. [PDF]

J Thorac Dis
Pujol JL.
europepmc   +1 more source

Expert Consensus on the Clinical Application of Poly ADP Ribose Polymerase Inhibitors in Breast Cancer (2025 Edition). [PDF]

Cancer Innov
Ma F, Xu B, China Anti‐Cancer Association Committee on Clinical Research of Anticancer Drugs, National Expert Committee on Monitoring Clinical Application of Antineoplastic Drugs, Breast Cancer Expert Committee of National Cancer Quality Control Center, Expert Committee on Chemotherapy Quality Control of Beijing Cancer Treatment Quality Control and Improvement Center.   +5 more
europepmc   +1 more source

Hydroxysafflor yellow a attenuates oxygen-glucose deprivation/ reoxygenation induced endothelial pyroptosis via PARP-1/NLRP3 pathway. [PDF]

Front Pharmacol
Huang Q, Shi S, Qian L, Wu Y, Mao B, Chen N, Qian C, Guo Y, Jin B.   +8 more
europepmc   +1 more source

Dual PARP/Tankyrase Inhibition Enhances Antitumor Efficacy in PTEN-Deficient Endometrial Cancer. [PDF]

J Cell Mol Med
Kang SW, Eum H, Lee JY, Lee MS, Kim YM, Kim TW, Lee SW.   +6 more
europepmc   +1 more source

Neurotropic alphavirus infection induces PARP-1 hyperactivation-mediated energy collapse in motor neurons. [PDF]

J Virol
Williams RE, Pieterse L, Patel SS, McLaren MW, Elrick MJ, Griffin DE.   +5 more
europepmc   +1 more source

PARP1 as a novel therapeutic and diagnostic tool in autoimmune rheumatic diseases: a systematic literature review. [PDF]

Rheumatol Int
Dey M, Dey M.
europepmc   +1 more source

Radiogenomics and the DNA damage response: opportunities for biomarker-guided radiosensitization in pancreatic cancer. [PDF]

Front Oncol
Karam MN, Hajj J, Crane CH, Ramia P, Geara F, Hamadeh N, Scott JG, Grobmyer S, Almond R, O'Reilly EM, Hajj C.   +10 more
europepmc   +1 more source