Results 111 to 120 of about 24,141 (294)

The Rise of Particle Beam Therapy: Are We Ready for The Potential Game-Changer? [PDF]

Cancer Res Treat, 2021
Chie EK, Ahn YC.
europepmc   +1 more source

PAMELA Overview : design goals and principles

, 2009
The PAMELA (Particle Accelerator for MEdicaL Applications) project is to design an accelerator for proton and light ion therapy using non-scaling Fixed Field Alternating Gradient (FFAG) accelerators, as part of the CONFORM project, which is also ...
Easton, M.J., Tzenov, S.I., Khan, A., Pasternak, J., McIntosh, P.A., Witte, H., Johnstone, C., Bliss, N., Machida, S., Edgecock, R., Kelliher, D.J., Rogers, C.T., Peach, K. J., Owen, H.L., Fenning, R.J.L., Vojnovic, B., Barlow, Roger, Sheehy, S. L., Aslaninejad, M., Jones, B., Yokoi, T., Tygier, S.C., Beard, C.D., Pozimski, J.K., Seviour, Rebecca, Rochford, J., Cobb, J.H., Smith, S.L.   +27 more
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Clinical dosimetric impact of Acuros XB and analytical anisotropic algorithm (AAA) on real lung cancer treatment plans : review

, 2014
Photon dose calculation algorithms in treatment planning system could affect the accuracy of dose delivery when tissue heterogeneity is involved along the beam path.
Rana, Suresh; Department of Medical Physics, ProCure Proton Therapy Center, Oklahoma City, OK, USA.
core   +1 more source

Circular RNA circNrip1 Interacts with SYNCRIP to Promote Neuropathic Pain by Stabilizing Tlr2 mRNA in Primary Sensory Neurons

Advanced Science, EarlyView.
Model of circNrip1 (cNrip1) upregulation driving neuropathic pain mechanisms. After peripheral nerve injury, increased FUS triggers the formation and upregulation of cNrip1 in injured DRG neurons. Upregulated cNrip1 recruits SYNCRIP to the 3′‐UTR of Tlr2 mRNA by binding to both, thereby promoting SYNCRIP‐triggered Tlr2 mRNA stability and increasing ...
Xiaozhou Feng, Jifang Xiao, Congcong Huang, Bao‐Chun Jiang, Bing Wang, Xu Li, Shibin Du, Tolga Berkman, Chun‐Hsien Wen, Weihua Cai, Dilip Sharma, Kun Wang, Longfei Ma, Huijuan Hu, Yuan‐Xiang Tao   +14 more
wiley   +1 more source

Review of clinical results of charged‑particle therapy for esophageal cancer

, 2020
Esophageal cancer is one of the common causes of cancer-related death. The treatment for esophageal cancer, particularly unresectable cases, is a difficult problem.
Takashi, Ono, Ono, Takashi, 1016342, 1016341   +3 more
core   +1 more source

Synchrotron XRF Imaging Reveals Manganese Accumulation in the Golgi and Post‐Synapses of Neurons and Enhanced Uptake in Astrocytes

Advanced Science, EarlyView.
Despite widespread exposure, the mechanisms of manganese neurotoxicity remain poorly understood. Using correlative cryogenic fluorescence and synchrotron X‐ray fluorescence imaging techniques, we show that the Golgi apparatus is the primary accumulation site for manganese in both neurons and astrocytes, and that manganese targets the neuronal ...
Ines Kelkoul, Aiyarin Kittilukkana, Luis C. C. Huarte, Hiram Castillo‐Michel, Murielle Salome, Stéphane Roudeau, Pauline Belzanne, Matthieu Sainlos, Noémie Pied, Monica Fernandez‐Monreal, Daniel Choquet, Richard Ortega, Asuncion Carmona   +12 more
wiley   +1 more source

Beam angle selection incorporation of anatomical heterogeneities for pencil beam scanning charged-particle therapy

, 2016
In charged particle therapy with pencil beam scanning (PBS), localization of the dose in the Bragg peak makes dose distributions sensitive to lateral tissue heterogeneities.
稲庭 拓, 476953, 寅松 千枝, 476954, 476955, Toramatsu, Chie, Inaniwa, Taku, 476952   +7 more
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Carboranyl‐Curcuminoids for the Neutron Capture‐Based Treatment of Amyloid Aggregates in Alzheimer's Disease

Advanced Science, EarlyView.
The 10B‐enriched monocarbonyl analog of curcumin (BMAC) 10B‐9 enables site‐specific Boron Neutron Capture Therapy (BNCT) on amyloid‐β (Aβ) fibrils. Neutron irradiation induces histidine oxidation and fibril destabilization, as revealed by 1H‐NMR and FESEM analyses.
Sebastiano Micocci, Stefano Parisotto, Diego Alberti, Alberto Lanfranco, Valeria Bitonto, Polyssena Renzi, Martina Salmi, Andrea Magnani, Federica Dal Bello, Katiuscia Pagano, Laura Ragona, Nicoletta Protti, Annamaria Deagostino, Simonetta Geninatti Crich   +13 more
wiley   +1 more source

Ground-based passive generation of Solar Particle Event spectra: Planning and manufacturing of a 3D-printed modulator

Zeitschrift für Medizinische Physik
The generation of space radiation on Earth is essential to study and predict the effects of radiation on space travelers, electronics, or materials during future long-term space missions. Next to the heavy ions of the galactic cosmic rays, solar particle
Tabea Pfuhl, Uli Weber, Felix Horst, Marco Durante, Christoph Schuy   +4 more
doaj   +1 more source

Tissue substitutes for particulate radiations and their use in radiation dosimetry and radiotherapy

, 1978
PhDMost of the tissue substitute materials currently used inclinical radiation dosimetry are designed to simulate muscle or bone when irradiated with photons A few materials have been developed for neutron dosimetry, but substitutes speci fically ...
Constantinou, Christodoulos
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