Results 1 to 10 of about 164,484 (166)

Dose–Volume and Radiobiological Model-Based Comparative Evaluation of the Gastrointestinal Toxicity Risk of Photon and Proton Irradiation Plans in Localized Pancreatic Cancer Without Distant Metastasis

Frontiers in Oncology, 2020
Background: Radiobiological model-based studies of photon-modulated radiotherapy for pancreatic cancer have reported reduced gastrointestinal (GI) toxicity, although the risk is still high. The purpose of this study was to investigate the potential of 3D-
Vijay P. Raturi, Vijay P. Raturi, Taku Tochinai, Hidehiro Hojo, Toshiya Rachi, Kenji Hotta, Naoki Nakamura, Sadamoto Zenda, Atsushi Motegi, Takaki Ariji, Yasuhiro Hirano, Hiromi Baba, Hajime Ohyoshi, Masaki Nakamura, Masayuki Okumura, Yanping Bei, Tetsuo Akimoto, Tetsuo Akimoto   +17 more
doaj   +1 more source

Dose-response of deformable radiochromic dosimeters for spot scanning proton therapy

Physics and Imaging in Radiation Oncology, 2020
Intrafractional motion and deformation influence proton therapy delivery for tumours in the thorax, abdomen and pelvis. This study aimed to test the dose–response of a compressively strained three-dimensional silicone-based radiochromic dosimeter during ...
Simon V. Jensen, Lia B. Valdetaro, Per R. Poulsen, Peter Balling, Jørgen B.B. Petersen, Ludvig P. Muren   +5 more
doaj   +1 more source

Dosimetric feasibility of moderately hypofractionated/dose escalated radiation therapy for localised prostate cancer with intensity-modulated proton beam therapy using simultaneous integrated boost (SIB-IMPT) and impact of hydrogel prostate-rectum spacer

Radiation Oncology, 2022
Purpose To examine the dosimetric feasibility of hypofractionated/dose escalated radiation therapy in patients with localized prostate carcinoma using simultaneous integrated boost intensity-modulated proton beam therapy (SIB-IMPT) in absence or presence
Dalia Ahmad Khalil, Danny Jazmati, Dirk Geismar, Jörg Wulff, Christian Bäumer, Paul Heinz Kramer, Theresa Steinmeier, Stefanie Schulze Schleitthoff, Sandija Plaude, Martin Bischoff, Stephan Tschirdewahn, Boris Hadaschik, Beate Timmermann   +12 more
doaj   +1 more source

Normal tissue complication probability models for prospectively scored late rectal and urinary morbidity after proton therapy of prostate cancer

Physics and Imaging in Radiation Oncology, 2021
Background and purpose: Photons and protons have fundamentally different properties, i.e. protons have a reduced dose bath but a higher relative biological effectiveness. Photon-based normal tissue complication probability (NTCP) models may therefore not
Jesper Pedersen, Xiaoying Liang, Curtis Bryant, Nancy Mendenhall, Zuofeng Li, Ludvig P. Muren   +5 more
doaj   +1 more source

Dosimetric comparison between proton beam therapy and photon radiation therapy for locally advanced esophageal squamous cell carcinoma

Radiation Oncology, 2018
Background The purpose of this study was to perform a dosimetric comparison between proton beam therapy (PBT) and photon radiation therapy in patients with locally advanced esophageal squamous cell carcinoma (ESCC) who were treated with PBT in our ...
Yasuhiro Hirano, Masakatsu Onozawa, Hidehiro Hojo, Atsushi Motegi, Sadatomo Zenda, Kenji Hotta, Shunsuke Moriya, Hidenobu Tachibana, Naoki Nakamura, Takashi Kojima, Tetsuo Akimoto   +10 more
doaj   +1 more source

Proton Beam Therapy for Children With Neuroblastoma: Experiences From the Prospective KiProReg Registry

Frontiers in Oncology, 2021
ObjectiveRadiotherapy (RT) is an integral part of the interdisciplinary treatment of patients with high-risk neuroblastoma (NB). With the continuous improvements of outcome, the interest in local treatment strategies that reduce treatment-related side ...
Danny Jazmati, Sarina Butzer, Barbara Hero, Dalia Ahmad Khalil, Julien Merta, Christian Bäumer, Christian Bäumer, Christian Bäumer, Gina Plum, Jörg Fuchs, Friederike Koerber, Theresa Steinmeier, Sarah Peters, Jerome Doyen, Theresa Thole, Matthias Schmidt, Christoph Blase, Stephan Tippelt, Angelika Eggert, Rudolf Schwarz, Thorsten Simon, Beate Timmermann, Beate Timmermann   +22 more
doaj   +1 more source

Treatment plan comparison of proton vs photon radiotherapy for lower-grade gliomas

Physics and Imaging in Radiation Oncology, 2021
Background and purpose: Patients with lower-grade gliomas are long-term survivors after radiotherapy and may benefit from the reduced dose to normal tissue achievable with proton therapy.
Camilla S. Byskov, Christian R. Hansen, Rikke H. Dahlrot, Lene Haldbo-Classen, Charlotte A. Haslund, Flemming Kjær-Kristoffersen, Thomas O. Kristensen, Yasmin Lassen-Ramshad, Slávka Lukacova, Aida Muhic, Petra W. Nyström, Britta Weber, Jesper F. Kallehauge   +12 more
doaj   +1 more source

Circulating cell-free DNA as predictor of pathological complete response in locally advanced rectal cancer patients undergoing preoperative chemoradiotherapy

Clinical and Translational Radiation Oncology, 2022
Background: The watch and wait (W&W) strategy is proposed for patients with locally advanced rectal cancer (LARC) achieving clinical complete response (cCR) after neoadjuvant radiotherapy.
Christina Glismand Truelsen, Camilla Skovhus Kronborg, Brita Singers Sørensen, Louise Bach Callesen, Karen-Lise Garm Spindler   +4 more
doaj   +1 more source

Particle therapy in the future of precision therapy [PDF]

The British Journal of Radiology, 2020
The first hospital-based treatment facilities for particle therapy started operation about thirty years ago. Since then, the clinical experience with protons and carbon ions has grown continuously and more than 200,000 patients have been treated to date.
Lukas, Schaub, Semi Ben, Harrabi, Juergen, Debus   +2 more
openaire   +2 more sources

Evaluation of an a priori scatter correction algorithm for cone-beam computed tomography based range and dose calculations in proton therapy

Physics and Imaging in Radiation Oncology, 2020
Background and purpose: Scatter correction of cone-beam computed tomography (CBCT) projections may enable accurate online dose-delivery estimations in photon and proton-based radiotherapy.
Andreas Gravgaard Andersen, Yang-Kyun Park, Ulrik Vindelev Elstrøm, Jørgen Breede Baltzer Petersen, Gregory C. Sharp, Brian Winey, Lei Dong, Ludvig Paul Muren   +7 more
doaj   +1 more source