Results 41 to 50 of about 164,484 (166)

An interactive deep-learning workflow for head and neck gross tumour volume segmentation

Physics and Imaging in Radiation Oncology
Background and purpose: Deep learning (DL)-based auto-segmentation of head and neck cancer (HNC) gross tumour volumes remains challenging due to anatomical complexity and limited accuracy.
Zixiang Wei, Jintao Ren, Jesper Grau Eriksen, Kenneth Jensen, Hanna Rahbek Mortensen, Stine Sofia Korreman, Jasper Nijkamp   +6 more
doaj   +1 more source

Clinical implementation of intensity modulated proton therapy for testicular seminoma

Acta Oncologica
Background and purpose: We have previously shown that proton therapy results in considerable reduced doses to abdominal organs at risk (OAR) which likely reduces the patient’s risk of a second malignant tumor, which is vital for this young population ...
Heidi S. Rønde, Jesper F. Kallehauge, Morten Høyer, Anne Birgitte Als, Mads Agerbæk, Jakob Lauritsen, Peter M. Petersen, Lars Dysager, Camilla J.S. Kronborg   +8 more
doaj   +1 more source

Recent update of proton beam therapy for hepatocellular carcinoma: a systematic review and meta-analysis [PDF]

Journal of Liver Cancer
Backgrounds/Aims Although access to proton beam therapy (PBT) is limited worldwide, its use for the treatment of hepatocellular carcinoma (HCC) is gradually increasing with the expansion of new facilities.
Sun Hyun Bae, Won Il Jang, Hanna Rahbek Mortensen, Britta Weber, Mi Sook Kim, Morten Høyer   +5 more
doaj   +1 more source

Exploring Particle Therapy

, 2009
PTCOG 48; Meeting of the Particle Therapy Co-Operative ...
openaire   +1 more source

Acute toxicities in proton therapy for head and neck cancer – A matched analysis of the DAHANCA 35 feasibility study

Clinical and Translational Radiation Oncology
Background and purpose: As preparation for a national randomized study comparing proton radiotherapy to photon radiotherapy, DAHANCA 35, we performed a non-randomized pilot study to investigate patient selection, logistics, planning, and treatment ...
K. Nowicka-Matus, J. Friborg, C.R. Hansen, M. Bernsdorf, U.V. Elstrøm, M. Farhadi, C. Grau, J.G. Eriksen, J. Johansen, M.S. Nielsen, A. Holm, E. Samsøe, P. Sibolt, B. Smulders, K. Jensen   +14 more
doaj   +1 more source

Spread-out Bragg peak FLASH: quantifying normal tissue toxicity in a murine model

Frontiers in Oncology
ObjectiveA favorable effect of ultra-high dose rate (FLASH) radiation on normal tissue-sparing has been indicated in several preclinical studies. In these studies, the adverse effects of radiation damage were reduced without compromising tumor control ...
Line Kristensen, Line Kristensen, Line Kristensen, Per Rugaard Poulsen, Per Rugaard Poulsen, Eleni Kanouta, Eleni Kanouta, Sky Rohrer, Christina Ankjærgaard, Claus E. Andersen, Jacob G. Johansen, Jacob G. Johansen, Yuri Simeonov, Uli Weber, Cai Grau, Cai Grau, Brita Singers Sørensen, Brita Singers Sørensen, Brita Singers Sørensen   +18 more
doaj   +1 more source

3D Swin Transformer for patient-specific proton dose prediction of brain cancer patients

Acta Oncologica
Background and purpose: Accurate dose plans in proton radiotherapy with consistent target in complex anatomical regions such as the brain are crucial. This study investigates a Swin Transformer-based deep learning model for voxel-wise dose prediction in ...
Anne Haahr Andresen, Yasmin Lassen-Ramshad, Slávka Lukacova, Christian Rønn Hansen, Jesper Folsted Kallehauge   +4 more
doaj   +1 more source

Selection for proton radiotherapy of grade 1–3 glioma patients

Clinical and Translational Radiation Oncology
Background: For adult patients with grade 1–3 gliomas, identifying patients with an indication for proton therapy (PT) can be challenging due to sparse evidence supporting its benefits.
C.S. Byskov, A. Muhic, R.H. Dahlrot, C.A. Haslund, T.L. Guldberg, M. Høyer, P.W. Nyström, L. Dysager, S. Hansen, L. Haldbo-Classen, A.K. Trip, Y. Lassen-Ramshad, B. Weber, S. Lukacova, C.R. Hansen, J.F. Kallehauge   +15 more
doaj   +1 more source

Oral Lentinula edodes mycelia extract enhances the antitumor effect of radiotherapy via gut-associated activation of dendritic and cytotoxic T cells

Scientific Reports
Oral administration of Lentinula edodes mycelia extract (L.E.M.) has been shown to stimulate systemic T cell–mediated antitumor immunity and inhibit tumor growth in mice, suggesting its potential to modulate host immune responses.
Tsuguhide Takeshima, Yang Wang, Sumitaka Hasegawa   +2 more
doaj   +1 more source

Inter-fraction motion robustness in a prospective phase II trial on dose-escalated proton reirradiation for locally recurrent rectal cancer

Physics and Imaging in Radiation Oncology
Background and purpose: Intensity modulated proton therapy (IMPT) enables generation of conformal dose plans with organ at risk (OAR) sparing potential. However, pelvic IMPT robustness is challenged by inter-fraction motion caused by constant anatomical ...
C.G. Truelsen, H.S. Rønde, J.F. Kallehauge, L.Ø. Poulsen, B.M. Havelund, B.G. Pedersen, L.H. Iversen, K.G. Spindler, C.S. Kronborg   +8 more
doaj   +1 more source