Results 51 to 60 of about 164,484 (166)

Triggered plan adaptation using multi-image optimization for improved robustness in head-and-neck cancer proton therapy

Physics and Imaging in Radiation Oncology
Background and purpose: Anatomical variations in head-and-neck (HNC) proton therapy may degrade target coverage and organ-at-risk (OAR) sparing.
Nadine Vatterodt, Brian Winey, Stine S. Korreman   +2 more
doaj   +1 more source

Fixation method influences FLASH skin sparing in an in vivo leg model

Acta Oncologica
Background and purpose: The FLASH effect, where ultra-high dose rate elicits a favourable normal tissue-sparing, has been shown in several preclinical studies.
Line Kristensen, Cathrine Overgaard, Jacob Johansen, Anna Hansen, Niels Bassler, Per Poulsen, Brita Sørensen   +6 more
doaj   +1 more source

Exploring patient-reported barriers to participating in proton therapy clinical trials

Technical Innovations & Patient Support in Radiation Oncology
Introduction: Clinical trials lead the progress in healthcare. To ensure reliable research conclusions, it is essential to enroll diverse patient groups.
Anne Wilhøft Kristensen, Annesofie Lunde Jensen, Kenneth Jensen, Susanne Oksbjerre Dalton, Jeppe Friborg, Cai Grau   +5 more
doaj   +1 more source

Determining the effects of hyperthermia on the tumor and acute normal tissue response of FLASH radiation

Acta Oncologica
Introduction: There is limited indication of how hyperthermia would influence the unique proposition of FLASH radiation – its ability to maintain comparable tumor response while offering protection to normal tissues.
Priyanshu Manojkumar Sinha, Line Kristensen, Charlemagne Asonganyi Folefac, Lars Hjorth Præstegaard, Lone Hoffmann, Per Rugaard Poulsen, Michael Robert Horsman, Brita Singers Sørensen   +7 more
doaj   +1 more source

Proton beam therapy in paediatric radiation oncology: Defining the limitations, uncertainties and optimisation of treatment plans

EJC Paediatric Oncology
Proton Beam Therapy (PBT) is an increasingly utilised modality for treating tumours by utilising the physical properties of accelerated proton beams. This review explores the development of PBT, its dosimetric advantages over conventional x-ray-based ...
C.S.M. Gillies, P. Lim, C. Dunlea, B. Timmermann, C. Alapetite, S. Bolle, I.F. Kristensen, K. Seiersen, Y. Lassen-Ramshad   +8 more
doaj   +1 more source

Particle therapy [PDF]

The British Journal of Radiology, 2011
openaire   +1 more source

Cone-beam CT-based estimations of prostate motion and dose distortion during radiotherapy

Physics and Imaging in Radiation Oncology
Background and purpose: Intra-fractional prostate translational and rotational (6DoF) motion can cause dose distortions. As intra-fractional motion monitoring is often unavailable, this study compares three methods to use pre- and post-treatment cone ...
Karolina A Klucznik, Thomas Ravkilde, Simon Skouboe, Ditte S Møller, Steffen Hokland, Paul Keall, Simon Buus, Lise Bentzen, Per R Poulsen   +8 more
doaj   +1 more source

Preclinical study of reirradiation with hyperthermia in recurrent murine tumors and normal mouse skin

Acta Oncologica
Background: Re-irradiation is an essential treatment option for recurrent tumours but is limited by normal tissue tolerance. Hyperthermia can enhance radiation efficacy by impairing DNA repair and improving tumor oxygenation; however, limited preclinical
Charlemagne A Folefac, Priyanshu M. Sinha, Niels Bassler, Brita S. Sørensen, Michael R. Horsman   +4 more
doaj   +1 more source

[Heavy particle radiation therapy].

Anales del sistema sanitario de Navarra, 2011
The characteristics of radiation formed by heavy particles make it a highly useful tool for therapeutic use. Protons, helium nuclei or carbon ions are being successfully employed in radiotherapy installations throughout the world. This article sets out the physical and technological foundations that make these radiation particles suitable for attacking
S, Lozares, F, Mañeru, S, Pellejero
openaire   +1 more source

Charged Particle Therapy

Charged Particle Therapy
Particle beams such as protons and heavier ions show an increase in nergy deposition with penetration depth up to a maxi-mum at the end of their range, the so-called Bragg perk. Almost no dose is deposited in normal tissue beyond the Bragg peak. The particle range is determined by the energy of the incoming particles.
openaire