Results 91 to 100 of about 66,774 (189)

Impaired fast-spiking interneuron function in a genetic mouse model of depression

eLife, 2015
Rhythmic neuronal activity provides a frame for information coding by co-active cell assemblies. Abnormal brain rhythms are considered as potential pathophysiological mechanisms causing mental disease, but the underlying network defects are largely ...
Jonas-Frederic Sauer, Michael Strüber, Marlene Bartos   +2 more
doaj   +1 more source

Immunocytochemical profiles of inferior colliculus neurons in the rat and their changes with aging

Frontiers in Neural Circuits, 2012
The inferior colliculus (IC) plays a strategic role in the central auditory system in relaying and processing acoustical information, and therefore its age-related changes may significantly influence the quality of the auditory function.
Ladislav eOuda, Josef eSyka
doaj   +1 more source

Cortistain is expressed in a distinct subset of cortical interneurons [PDF]

, 1997
Cortistatin is a presumptive neuropeptide that shares 11 of its 14 amino acids with somatostatin. In contrast to somatostatin, administration of cortistatin into the rat brain ventricles specifically enhances slow wave sleep, apparently by antagonizing ...
Alcántara Horrillo, Soledad, Criado, José R., Danielson, Patria E., Henriksen, Steven J., Lecea Flores de Lemus, Luis de, Morales, Marisela, Río Fernández, José Antonio del, Soriano García, Eduardo, Sutcliffe, J. Gregor   +8 more
core  

A defined network of fast-spiking interneurons in orbitofrontal cortex: responses to behavioral contingencies and ketamine administration

Frontiers in Systems Neuroscience, 2009
Orbitofrontal cortex (OFC) is a region of prefrontal cortex implicated in the motivational control of behavior and in related abnormalities seen in psychosis and depression.
Michael C Quirk, Dara L Sosulski, Claudia E Feierstein, Claudia E Feierstein, Naoshige Uchida, Zachary F Mainen, Zachary F Mainen   +6 more
doaj   +1 more source

Parvalbumin increases in the medial and lateral geniculate nuclei of aged rhesus macaques.

Frontiers in Aging Neuroscience, 2013
Subcortical auditory structures in the macaque auditory system increase their densities of neurons expressing the calcium binding protein parvalbumin (PV) with age.
Daniel T Gray, Megan L. Rudolph, James R. Engle, James R. Engle, Gregg H Recanzone, Gregg H Recanzone   +5 more
doaj   +1 more source

Control of neuronal excitability by calcium binding proteins : a new mathematical model for striatal fast-spiking interneurons.

Frontiers in Molecular Neuroscience, 2012
Calcium binding proteins, such as parvalbumin, are abundantly expressed in very distinctive patterns in the central nervous system but their physiological function remains poorly understood.
Don Patrick eBischop, David eOrduz, Laurie eLambot, Serge N. Schiffmann, David eGall   +4 more
doaj   +1 more source

Parvalbumin interneuron deficits in schizophrenia

European Neuropsychopharmacology
Parvalbumin-expressing (PV+) interneurons represent one of the most abundant subclasses of cortical interneurons. Owing to their specific electrophysiological and synaptic properties, PV+ interneurons are essential for gating and pacing the activity of excitatory neurons.
openaire   +2 more sources

Parvalbumin Interneurons: All Forest, No Trees [PDF]

Neuron, 2015
There has been a surge of interest in how inhibitory neurons influence the output of local circuits in the brain. In this issue of Neuron, Scholl et al. (2015) provide a compelling argument for what one class of inhibitory neurons actually does.
openaire   +4 more sources

Behavioral and other phenotypes in a cytoplasmic Dynein light intermediate chain 1 mutant mouse [PDF]

, 2011
The cytoplasmic dynein complex is fundamentally important to all eukaryotic cells for transporting a variety of essential cargoes along microtubules within the cell. This complex also plays more specialized roles in neurons.
AlQatari, Mona, Banks, Gareth T, Haas, Matilda A, Hafezparast, Majid, Line, Samantha, others,, Philpott, Amelia, Rishal, Ida, Shepherd, Hazel L, Stewart, Sammy   +9 more
core   +1 more source

Infralimbic parvalbumin neural activity facilitates cued threat avoidance

eLife
The infralimbic cortex (IL) is essential for flexible behavioral responses to threatening environmental events. Reactive behaviors such as freezing or flight are adaptive in some contexts, but in others a strategic avoidance behavior may be more ...
Yi-Yun Ho, Qiuwei Yang, Priyanka Boddu, David A Bulkin, Melissa R Warden   +4 more
doaj   +1 more source