Results 71 to 80 of about 1,240,534 (281)

Coming Out as a Secular Rite of Passage – a Lived Experience Study Based on Diary Narratives of the Polish LGBTQ+ Community

European Journal of Life Writing
In the article I examine whether an act of coming out of an LGBT+ person can be perceived as an existencial equvalent of a religious rite of passage. Paper contains an analysis of fragments of diaries from the collective volume All the Strength I Draw ...
Joanna Anczaruk
doaj   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

The Pragmatism of Politics: Senator Norris Cotton and the Civil Rights Legislation in the 1960s [PDF]

, 2017
In the mid-1960s, the United States Congress passed two laws that would reshape the course of the history of the United States: the Civil Rights Act (CRA) of 1964 and the Voting Rights Act (VRA) of 1965.
Sanborn, Ryan
core   +1 more source

Making the created pass into the uncreated. A passing to the act; an act of passage.

, 2016
Faire passer du créé dans l'incréé. Un passage à l'acte, acte de passage. Pour aborder la question de l'action de l'art, je vais partir d'un concept relevé par Simone Weil : la décréation. Nous allons explorer la nature de ce concept pour le mettre en relation avec l'art et ses modalités contemporaines à travers le numérique et l'internet avec ce ...
openaire   +3 more sources

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Company Law Modernisation and Corporate Governance in the United Kingdom

Victoria University Law and Justice Journal, 2011
Many elements of British company law are deeply embedded in nineteenth-century assumptions. Change has come very slowly when efforts have been made to modernise company law in the United Kingdom.
Roman Tomasic
doaj   +1 more source

A low-water crossing impacts Northern Hog Sucker Hypentelium nigricans movement in an Ozark stream

Journal of Freshwater Ecology, 2020
Streams are complex systems that rely on connectivity to maintain natural ecological function. Low-water crossings are common in small-intermediate sized streams and can restrict longitudinal movement of fishes.
Jeffrey M. Williams, Hope R. Dodd, Debra S. Finn   +2 more
doaj   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

A Lobbying Approach to Evaluating the Sarbanes-Oxley Act of 2002 [PDF]

We evaluate the net benefits of the Sarbanes-Oxley Act (SOX) for shareholders by studying the lobbying behavior of investors and corporate insiders to affect the final implemented rules under the Act.
Annette Vissing-Jorgensen, Paola Sapienza, Yael V. Hochberg   +2 more
core  

Inhibición y acto. Un recorrido por tenues laberintos del tiempo

Desde el Jardín de Freud, 2009
Resumen Este texto cuestiona la oposición radical entre inhibición y acto a partir de una intrincación temporal que nos permite descubrir en la inhibición algo de “la luminosidad del acto” y en el acto, algo de “la inhibición atenta”, aplicada, que exige
Patricia León-López
doaj   +2 more sources