Results 121 to 130 of about 38,690 (242)

Induced Proprioceptor and Low‐Threshold Mechanoreceptor Neurons Derived from Human Pluripotent Stem Cells Exhibit Distinct Functional Mechanosensory Properties

Advanced Science, EarlyView.
This study describes derivation of two distinct mechanosensory subpopulations from human pluripotent stem cells using a transcription factor mediated approach. Of significance, functional interrogation of induced mechanosensory subtypes reveal their unique responses to mechanical stimulation in the absence of end‐organs.
Amy J. Hulme, Rocio K. Finol‐Urdaneta, Jeffrey R. McArthur, Nicholas R. Marzano, Simon Maksour, Amarinder Thind, Yang Guo, Dominic Kaul, Marnie Maddock, Oliver Friedrich, Boris Martinac, David J. Adams, Mirella Dottori   +12 more
wiley   +1 more source

All-optical diamond heater-thermometer enables versatile and reliable thermal modulation of ion channels at the single-cell level. [PDF]

Biophys J
Rougier JS, Glushkov E, Guichard S, Kucera J, Zeeb V, Abriel H.   +5 more
europepmc   +1 more source

Unraveling the Morphological and Functional Maturation Mechanisms Underlying Human Neural Development Using iPSCs‐Derived Neuronal Model

Advanced Science, EarlyView.
Using human induced pluripotent stem cells (hiPSCs)‐derived neuronal model, Tian and colleagues reveal that voltage‐gated calcium channels Cav1.2 and Cav1.3, and their mediated calcium ion influx, are essential for early morphogenesis of human neuronal development, while ECEL1 underlies human neuronal functional developmental maturation through CALM3 ...
Yue Tian, Yi‐Chun Ou, Zi‐Xian Zhang, Jie Cai, Si‐Qing Cai, Guo‐Gang Xing   +5 more
wiley   +1 more source

Modeling internal charge effects on capacitor dynamics for non-invasive estimation of membrane potential. [PDF]

Biol Methods Protoc
Ma X.
europepmc   +1 more source

Pneumatically‐Actuated Liquid Metal‐Based Frequency Reconfigurable Antenna

Advanced Science, EarlyView.
A look at a flexible, frequency‐tuning antenna A Soft Solution: Introducing a new antenna design made with liquid metal composites. A Full Package: Combining flexible antennas with pneumatic actuators. End‐to‐End Control: Automatic reconfiguration according to signal strength.
Yiwen Song, Aditya Bharambe, Dinesh K. Patel, Barbara Zhuo, Mason Zadan, Carmel Majidi, Swarun Kumar   +6 more
wiley   +1 more source

Robotic posterior bar decalcification and mitral repair in mitral annular calcification. [PDF]

Ann Cardiothorac Surg
Loulmet DF, Hage A, Grossi EA.
europepmc   +1 more source

Astrocytic PCBP1 Suppresses Ferroptosis to Restore Glutamatergic Homeostasis and Mitigate Stress‐Induced Depression in Male Mice

Advanced Science, EarlyView.
This study demonstrates that polyC‐RNA‐binding protein 1 (PCBP1) in ventral hippocampal astrocytes modulates depressive‐like behaviors by regulating glutathione peroxidase 4‐mediated ferroptosis and synaptic glutamatergic transmission. PCBP1 overexpression intervention in the chronic unpredictable mild stress model rescues behavioral deficits ...
Jinyu Zhang, Binbin Zhao, Min Jia, Yan Zhao, Ye Lu, Wenyu Xi, Ziyu Zhu, Xiaojuan Gong, Qingyan Ma, Yuan Gao, Yijie Guo, Pan Li, Feng Zhu, Shuguang Wei, Xiancang Ma, Yunpeng Wang   +15 more
wiley   +1 more source

Cost-Effective and Rapid Detection of Tetrodotoxin Using Indium Tin Oxide Electrodes via In Vitro Electrophysiology and Electrochemistry. [PDF]

Toxins (Basel)
Pandurangi NAC, Santafe MM, Tudo A, Ozsoy N, Sureda FX, Dallas ML, Katakis I.   +6 more
europepmc   +1 more source

Hungry for Knowledge: Octopamine Signaling Regulates Hunger‐Enhanced Olfactory Learning

Advanced Science, EarlyView.
Researchers demonstrate that hunger state facilitates both aversive and appetitive olfactory learning. Two distinct octopamine signaling pathways are involved in aversive or appetitive memory formation in the hunger state. And, hunger state also facilitates the formation of both types of memories via an evolutionarily conserved norepinephrine (the ...
Huijuan Zhao, Guiyuan Shi, Ruixue Qin, Yinghao Sun, Wenbo Guo, Ruixia Shi, Minxian Peng, Jingxuan Yang, Jianjian Zhao, Qiuhan Liu, Jun Xiao, Ke Zhang, Qiang Liu, Wenxing Yang, He Liu   +14 more
wiley   +1 more source

NIR‐Triggered Upconversion‐Perovskite Heterostructures for Non‐Genetic, Implant‐Free Optoelectronic Neuromodulation

Advanced Science, EarlyView.
The Single‐Nanostructured Optoelectronic Vehicle for neuromodulation Activation (SNOVA) establishes a paradigm for non‐genetic, implant‐free neuromodulation. By integrating NIR‐excitable UCNPs with broadband‐absorbing perovskite QDs, SNOVA efficiently converts deeply penetrating light into localized electric fields that modulate neuronal ion dynamics ...
Luyue Jiang, Chenguang Ma, Yiping Zhao, Jiazhi Li, Gen Li, Shuang Jin, Haoyang Su, Ye Tian, Yingkang Yang, Yunfu Luo, Lei Huang, Peijie Chen, Yiming Gao, Yi Wei, Yike Xiang, Lunming Qin, Kaihuan Zhang, Yifei Ye, Pengyi Tang, Liuyang Sun   +19 more
wiley   +1 more source