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Patch Clamp Techniques for Plant Cells
2012The study of electrophysiological processes at the molecular level, with exquisite sensitivity and full control over the experimental conditions, is possible with the patch clamp technique. A concise overview is given of the different configurations that are used with the technique.
Theo Elzenga
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The Patch Clamp Technique: Principles and Technical Considerations
Journal of Veterinary Cardiology, 2007The development of techniques that allow the high fidelity measurement of small scale ionic currents ushered in a new era of investigation into the role of ion channels in the physiologic and pathophysiologic function of excitable tissue. Based upon the formation of a high resistance (gigaohm) seal with the membrane of the cell being studied, these ...
Bruce G Kornreich
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Force-Controlled Patch Clamp of Beating Cardiac Cells [PDF]
Nano Letters, 2015 From its invention in the 1970s, the patch clamp technique is the gold standard in electrophysiology research and drug screening because it is the only tool enabling accurate investigation of voltage-gated ion channels, which are responsible for action ...
János Voros +2 more
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[1] Patch clamp techniques: An overview
, 1992 This chapter provides an overview of the patch clamp techniques. The patch clamp technique provides the experimental means for merging the tools of modern molecular and cellular biology with those of electrophysiology.
Michael Cahalan, Erwin Neher
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Neurosurgery, 1995
The introduction of the patch clamp technique less than two decades ago revolutionized the study of cellular physiology by providing a high-resolution method of observing the function of individual ionic channels in a variety of normal and pathological cell types.
L K, Liem +3 more
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The introduction of the patch clamp technique less than two decades ago revolutionized the study of cellular physiology by providing a high-resolution method of observing the function of individual ionic channels in a variety of normal and pathological cell types.
L K, Liem +3 more
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The Patch Clamp Technique in Ion Channel Research
Current Pharmaceutical Biotechnology, 2004To understand the pathogenesis of a given ion channel disorder, knowledge of the mutation alone is insufficient, instead, the description of the associated functional defect is decisive. The patch clamp technique enables to achieve this both in native tissue as well as heterologous expression systems. By this technique, structure-function relationships
K, Jurkat-Rott, F, Lehmann-Horn
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1995
In this chapter, I shall explain how to set-up a patch-clamp technique. The aim is to guide researchers in their initial steps in the field of electrophysiology, describing the instrumentation needed, as well as the technique itself. This chapter has been written assuming that the reader has a basic knowledge of electrophysiology.
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In this chapter, I shall explain how to set-up a patch-clamp technique. The aim is to guide researchers in their initial steps in the field of electrophysiology, describing the instrumentation needed, as well as the technique itself. This chapter has been written assuming that the reader has a basic knowledge of electrophysiology.
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Patch-clamp technique in renal physiology
American Journal of Physiology-Renal Physiology, 1986The patch-clamp technique of Neher and Sakmann and their colleagues has been widely used over the last 5 years to investigate ion channels in excitable tissues. More recently, it has become useful as a tool to study channels involved in transepithelial ion transport.
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Patch clamp techniques: an overview.
Methods in enzymology, 1992This chapter provides an overview of the patch clamp techniques. The patch clamp technique provides the experimental means for merging the tools of modern molecular and cellular biology with those of electrophysiology. Using various recording configurations, it is possible to dissect the mechanisms of channel modulation.
M, Cahalan, E, Neher
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