Results 61 to 70 of about 5,720,247 (293)

Architected Bio‐Based Iontronic Skin With Dual‐Mode Pressure and Strain Sensing

Advanced Functional Materials, EarlyView.
Bio‐based acrylates in combination with an ionic liquid create 3D‐printed ionogels with compositionally tuneable mechanics and ionic conductivity. Gyroid architectures amplify low‐pressure sensitivity while preserving robust strain sensing, enabling dual‐mode detection of pressure and deformation.
Maksims Jurinovs, Madara Veseta, Fevzihan Basarir, Beatrise Silava, Eduards Bakis, Krisjanis Smits, Olesja Starkova, Jaana Vapaavuori, Sergejs Gaidukovs   +8 more
wiley   +1 more source

Human iPSC‐Derived Tissue‐Engineered Nigrostriatal Pathway for Chronic Restoration of Dopaminergic Axon Tracts in a Rat Parkinson's Model

Advanced Healthcare Materials, EarlyView.
Inspired by conventional cell therapy and emerging bioengineering approaches, the tissue‐engineered nigrostriatal pathway (TE‐NSP) has an anatomically‐inspired design comprising a population of human dopaminergic neurons with unidirectional, long‐projecting axon tracts.
Wisberty J. Gordián‐Vélez, Dimple Chouhan, Kevin D. Browne, James Lim, Saarang P. Karandikar, Rodrigo A. España, John E. Duda, H. Isaac Chen, D. Kacy Cullen   +8 more
wiley   +1 more source

The Use of Tethered Bilayer Lipid Membranes to Identify the Mechanisms of Antimicrobial Peptide Interactions with Lipid Bilayers

Antibiotics, 2019
This review identifies the ways in which tethered bilayer lipid membranes (tBLMs) can be used for the identification of the actions of antimicrobials against lipid bilayers.
Amani Alghalayini, Alvaro Garcia, Thomas Berry, Charles G. Cranfield   +3 more
doaj   +1 more source

Measuring Blood Plasma Glutamine Levels Using a Nanopore‐Based Sensor

Advanced Healthcare Materials, EarlyView.
Glutamine (GLN) is a biomarker useful for predicting toxic ammonia accumulation. Here, we used a biosensor based on the Cytolysin A (ClyA) nanopore coupled with the GLN‐specific protein substrate‐binding domain 2 (SBD2) to demonstrate real‐time measurement of GLN in blood plasma, highlighting the potential for future point‐of‐care applications ...
Sofia B. Relvas, Iris M. Kormelink, Sandra Michel‐Souzy, Florian L. R. Lucas, Nieck J. van der Heide, Hans R. Waterham, Ramon Versteeg, Judith Jans, Loes I. Segerink, Carsten Wloka   +9 more
wiley   +1 more source

Correlated spontaneous activity persists in adult retina and is suppressed by inhibitory inputs. [PDF]

PLoS ONE, 2013
Spontaneous rhythmic activity is a hallmark feature of the developing retina, where propagating retinal waves instruct axonal targeting and synapse formation.
Abduqodir H Toychiev, Christopher W Yee, Botir T Sagdullaev   +2 more
doaj   +1 more source

LEAD: Literature Enhanced Ab Initio Discovery of Nitride Dusting Layers for Enhanced Tunnel Magnetoresistance and Lower Resistance Magnetic Tunnel Junctions

Advanced Materials, EarlyView.
Magnetic tunnel junctions (MTJs) using MgO tunnel barriers face challenges of high resistance‐area product and low tunnel magnetoresistance (TMR). To discover alternative materials, Literature Enhanced Ab initio Discovery (LEAD) is developed. The LEAD‐predicted materials are theoretically evaluated, showing that MTJs with dusting of ScN or TiN on ...
Sabiq Islam, William S. Rogers, Chen‐Yu Hu, Ming‐Yuan Song, Xinyu Bao, Shehrin Sayed, Jean Anne C. Incorvia   +6 more
wiley   +1 more source

Modeling cardiac electrical activity using cardiac organoids for drug screening

Pharmacological Research
Arrhythmia is one of the leading causes of mortality and lacks diagnostic and therapeutic options. Electrical activity at the cellular level is difficult to use as a basis for evaluating drug effects on cardiac rhythm. Cardiac organoids, as organized and
Qi Zhang, Nana Yang, Jiahong Chen, Jie Chen, Lu Fang, Yujie Zhu, Xiaoyi Liu, Zeshan Zhang, Guoliang Hao, Chenguang Niu, Yang Li, Lemin Zheng, Lingyun Zu   +12 more
doaj   +1 more source

¬cAMP promotes the differentiation of neural progenitor cells in vitro via modulation of voltage-gated calcium channels

Frontiers in Cellular Neuroscience, 2013
The molecular mechanisms underlying the differentiation of neural progenitor cells (NPCs) remain poorly understood. In this study we investigated the role of Ca2+ and cAMP (cyclic adenosine monophosphate) in the differentiation of NPCs extracted from the
Guilherme eLepski, Guilherme eLepski, Cinthia Elim Jannes, Guido eNikkhah, Josef eBischofberger   +4 more
doaj   +1 more source

Rediscovering sperm ion channels with the patch-clamp technique [PDF]

Molecular Human Reproduction, 2011
Upon ejaculation, mammalian spermatozoa have to undergo a sequence of physiological transformations within the female reproductive tract that will allow them to reach and fertilize the egg. These include initiation of motility, hyperactivation of motility and perhaps chemotaxis toward the egg, and culminate in the acrosome reaction that permits sperm ...
Yuriy, Kirichok, Polina V, Lishko
openaire   +2 more sources

Can Elastomers Combine Stiffness, Toughness and Fatigue Resistance?

Advanced Materials, EarlyView.
This review studies how the molecular and macroscopic architecture of elastomers influence their mechanical properties including: stiffness, stretchability, toughness, fatigue resistance, and damping behavior. By linking the structure to performance, it proposes design principles for advanced elastomeric systems that combine mechanical properties ...
Eva Baur, Esther Amstad
wiley   +1 more source