Results 41 to 50 of about 5,720,247 (293)

Patch-Clamp Proteomics of Single Neurons in Tissue Using Electrophysiology and Subcellular Capillary Electrophoresis Mass Spectrometry

open access: yes, 2021
Understanding of the relationship between cellular function and molecular composition holds a key to next-generation therapeutics but requires measurement of all types of molecules in cells.
Abigail M. Polter (11885712)   +5 more
core   +2 more sources

Cell model of catecholaminergic polymorphic ventricular tachycardia reveals early and delayed afterdepolarizations. [PDF]

open access: yesPLoS ONE, 2012
BACKGROUND: Induced pluripotent stem cells (iPSC) provide means to study the pathophysiology of genetic disorders. Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a malignant inherited ion channel disorder predominantly caused by ...
Kirsi Kujala   +12 more
doaj   +1 more source

Patch Clamp

open access: yes, 2018
Patch clamp recordings of sodium currents and action potentials from isolated adult guinea pig ventricular ...
Lori Isom (5639996)   +29 more
core   +1 more source

Investigation of Resonance Characteristics of More Than 10 000 Metal‐Coated Silicon MEMS Cantilevers Using Machine Learning

open access: yesAdvanced Engineering Materials, EarlyView.
More than 10 000 metal‐coated silicon MEMS cantilevers are fabricated and characterized to build a large‐scale experimental dataset spanning multiple vibrational modes. Machine learning algorithms are benchmarked to predict resonance frequency and quality factor, with ensemble based models achieving accuracy approaching experimental uncertainty.
Sina Zare Pakzad   +8 more
wiley   +1 more source

Nervous System of Periplaneta americana Cockroach as a Model in Toxinological Studies: A Short Historical and Actual View

open access: yesJournal of Toxicology, 2012
Nervous system of Periplaneta americana cockroach is used in a wide range of pharmacological studies, including electrophysiological techniques. This paper presents its role as a preparation in the development of toxinological studies in the following ...
Maria Stankiewicz   +2 more
doaj   +1 more source

RyR2 modulates a Ca2+-activated K+ current in mouse cardiac myocytes. [PDF]

open access: yesPLoS ONE, 2014
In cardiomyocytes, Ca2+ entry through voltage-dependent Ca2+ channels (VDCCs) binds to and activates RyR2 channels, resulting in subsequent Ca2+ release from the sarcoplasmic reticulum (SR) and cardiac contraction.
Yong-Hui Mu   +7 more
doaj   +1 more source

manual patch clamp raw.zip

open access: yes, 2017
Raw data on manual patch clamp measurements are stored under manual patch clamp raw. The first detachment tests subfolder contains data on the experiments with the three Accutase, Trypsin, and Detachin solutions.
Denise Franz (3696583)   +3 more
core   +1 more source

Counterion Dependent Side‐Chain Relaxation Stiffens a Chemically Doped Thienothiophene Copolymer

open access: yesAdvanced Functional Materials, EarlyView.
Oxidation of a thienothiophene copolymer, p(g3TT‐T2), via different doping strategies and dopant molecules resulted in materials with similar oxidation levels and a high electrical conductivity of ≈100 S cm−1. However, mechanical properties varied significantly, with sub‐glass transition temperatures and elastic moduli spanning from –44°C to –3°C and ...
Mariavittoria Craighero   +12 more
wiley   +1 more source

Advanced patch-clamp techniques and single-channel analysis

open access: yes, 1999
Much of our knowledge of ion-transport mechanisms in plant cell membranes comes from experiments using voltage-clamp. This technique allows the measurement of ionic currents across the membrane, whilst the voltage is held under experimental control.
Maathuis, FJM   +5 more
core   +1 more source

Biocytin-Labeling in Whole-Cell Recording: Electrophysiological and Morphological Properties of Pyramidal Neurons in CYLD-Deficient Mice

open access: yesMolecules, 2023
Biocytin, a chemical compound that is an amide formed from the vitamin biotin and the amino acid L-lysine, has been used as a histological dye to stain nerve cells.
Shuyi Tan   +6 more
doaj   +1 more source

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