Results 71 to 80 of about 38,690 (242)

Decellularized Extracellular Matrix (dECM) in Tendon Regeneration: A Comprehensive Review

Advanced Healthcare Materials, EarlyView.
Decellularized Extracellular Matrix (dECM) offers a promising solution by replicating the native tendon microenvironment and promoting regeneration. This review highlights advances in the decellularization methods, as well as their integration with emerging technologies and translational progress in tendon tissue engineering.
Kumaresan Sakthiabirami, Yeonwoo Park, Seong Kyeong Jo, Min Hee Kim, Jae Hwang Song   +4 more
wiley   +1 more source

Understand spiciness: mechanism of TRPV1 channel activation by capsaicin

Protein & Cell, 2017
Capsaicin in chili peppers bestows the sensation of spiciness. Since the discovery of its receptor, transient receptor potential vanilloid 1 (TRPV1) ion channel, how capsaicin activates this channel has been under extensive investigation using a variety ...
Fan Yang, Jie Zheng
doaj   +1 more source

Transistor‐Level Activation Functions via Two‐Gate Designs: From Analog Sigmoid and Gaussian Control to Real‐Time Hardware Demonstrations

Advanced Materials, EarlyView.
Screen gate‐based transistors are presented, enabling tunable analog sigmoid and Gaussian activations. The SA‐transistor improves MRI classification accuracy, while the GA‐transistor supports precise Gaussian kernel tuning for forecasting. Both functions are implemented in a single device, offering compact, energy‐efficient analog AI processing ...
Junhyung Cho, Youngmin Han, Won Woo Lee, Youngwoo Yoo, Kannan Udaya Mohanan, Chang‐Hyun Kim, Junhwan Choi, Young‐Joon Kim, Wonjun Shin, Hocheon Yoo   +9 more
wiley   +1 more source

Self‐Assembled Inorganic Nanomembrane Tubes: Rolled‐Up Piezoelectrics for Microacoustic Wave‐Based Actuators and Sensors

Advanced Materials, EarlyView.
This study demonstrates a self‐assembly process to generate free‐standing piezoelectric nanomembranes, forming ultracompact microtubular acoustic wave sensors and actuators. The miniaturized 3D piezoelectric platform reported in this work can be applied in telecommunication, energy harvesting, and acoustofluidics. Moreover, the 3D self‐assembly can add
Raphaël C. L‐M. Doineau, Christian N. Saggau, Stefan Baunack, Thomas Gemming, Yara Abdelaal, Robert Weser, Oliver G. Schmidt, Hagen Schmidt, Andreas Winkler, Mariana Medina‐Sánchez   +9 more
wiley   +1 more source

Reduced Ca²⁺ transport across sarcolemma but enhanced spontaneous activity in cardiomyocytes isolated from left atrium-pulmonary veins tissue of myopathic hamster

Journal of Biomedical Science, 2009
Background Several lines of evidence point to a particularly important role of the left atrium (LA) in initiating and maintaining atrial fibrillation (AF). This role may be related to the location of pulmonary veins (PVs) in the LA.
Chen Yao-Chang, Wu Kuo-Ho, Loh Yue-Xia, Hsu Chih-Hsiung, Wei Jeng, Lin Cheng-I   +5 more
doaj   +1 more source

Peptide‐Induced Ferroelectricity in Charge‐Transfer Supramolecular Materials

Advanced Materials, EarlyView.
Bio‐inspired supramolecular charge‐transfer amphiphiles self‐assemble into nanoribbons in water, where peptide chirality‐induced symmetry breaking generates robust ferroelectricity across multiple systems. These water‐processable organic ferroelectrics also enhance neuronal outgrowth and electrophysiological maturity, offering a versatile strategy for ...
James V. Passarelli, Yang Yang, Cara S. Smith, Jing Hao, Dhwanit R. Dave, Ashwin Narayanan, Zaida Álvarez, Broderick K. Johnson, Kelly A. Marshall, Ivan Fithian, Hiroaki Sai, Ruomeng Qiu, Charlotte L. Stern, Liam C. Palmer, Evangelos Kiskinis, Samuel I. Stupp   +15 more
wiley   +1 more source

PKA and PKC Modulators Affect Ion Channel Function and Internalization of Recombinant Alpha1 and Alpha1-Beta Glycine Receptors

Frontiers in Molecular Neuroscience, 2018
Glycine receptors (GlyRs) are important mediators of fast inhibitory neurotransmission in the mammalian central nervous system. Their function is controlled by multiple cellular mechanisms, including intracellular regulatory processes. Modulation of GlyR
Ulrike Breitinger, Lamiaa M. Bahnassawy, Dieter Janzen, Vera Roemer, Cord-Michael Becker, Carmen Villmann, Hans-Georg Breitinger   +6 more
doaj   +1 more source

A Wearable, Dual Closed‐loop Insulin Delivery System for Precision Diabetes Management

Advanced Materials, EarlyView.
A wearable dual closed‐loop drug delivery system for diabetes management is presented, featuring an adaptive, on‐body trained edge AI algorithm for precise insulin delivery, which enhances therapeutic accuracy from 92.10% to 98.82%. Abstract Effective blood glucose management is an increasing demand worldwide.
Xuecheng He, Wei Huang, Wensheng Lin, Binbin Cui, Xinyu Tian, Jing Bai, Dingyao Liu, Ivo Pang, Hao Huang, Shixian Lin, Jixiang Zhu, Jinqiang Wang, Shiming Zhang   +12 more
wiley   +1 more source

Imaging single-channel calcium microdomains by total internal reflection microscopy

Biological Research, 2004
The microdomains of Ca2+ in the cytosol around the mouth of open Ca2+ channels are the basic `building blocks' from which cellular Ca2+ signals are constructed.
ANGELO DEMURO, IAN PARKER
doaj  

Improving Ionic Conformality Across Polymer Electrolyte|Electrode Interfaces

Advanced Materials, EarlyView.
Polymer electrolytes typically form physically intimate electrode interfaces but often fail to maintain continuous ionic pathways, critically limiting battery performance. Through strategic compositional design, this study introduces a molecular ionic composite electrolyte that effectively reduces interfacial ionic depletion, ensuring consistent ion ...
Jungki Min, Nicholas F. Pietra, Callum Connor, Zhaohui Liang, Erin C. Jackson, Lei Tao, Dawei Xia, Xu Feng, Dominik Wierzbicki, Seong‐Min Bak, Robert B. Moore, Louis A. Madsen, Feng Lin   +12 more
wiley   +1 more source