Results 101 to 110 of about 6,734 (227)

The Role of Oral Pathobionts in Dysbiosis during Periodontitis Development [PDF]

Journal of Dental Research, 2014
An emerging concept is the tight relationship between dysbiosis (microbiota imbalance) and disease. The increase in knowledge about alterations in microbial communities that reside within the host has made a strong impact not only on dental science, but also on immunology and microbiology as well as on our understanding of several diseases ...
Y, Jiao, M, Hasegawa, N, Inohara
openaire   +2 more sources

Characterization of the human gut virome in metabolic and autoimmune diseases

Inflammation and Regeneration, 2022
The intestinal microbiome is dominated by bacteria and plays a pivotal role in the occurrence and development of disease, including several metabolic and autoimmune disorders.
Kosuke Fujimoto, Daichi Miyaoka, Satoshi Uematsu   +2 more
doaj   +1 more source

Correlation Between Gut Microbiota, Metabolites, and Diabetic Complications: A Two‐Sample Mendelian Randomization Study

Medicine Advances, EarlyView.
Fang et al. demonstrate a significant causal relationship among gut microbiota, gut metabolites, and diabetic complications, highlighting a biological link underlying mechanisms of diabetic vascular diseases. These findings provide important implications for future therapeutic strategy and risk prediction.
Jiaxi Fang, Leilei Zhai, Chan Huang, Liqin Li, Yong Wang, Jiaojiao Fan, Wei Zhou   +6 more
wiley   +1 more source

Akkermansia muciniphila inversely correlates with the onset of inflammation, altered adipose tissue metabolism and metabolic disorders during obesity in mice [PDF]

, 2016
Recent evidence indicates that the gut microbiota plays a key role in the pathophysiology of obesity. Indeed, diet-induced obesity (DIO) has been associated to substantial changes in gut microbiota composition in rodent models. In the context of obesity,
Cani, P. D., Claret i Carles, Marc, Delzenne, NM., Everard, A., Gomis, Ramon, 1946-, Gómez Valadés, Alicia G., Matamoros, S., Ramírez, Sara, Schneeberger, Marc   +8 more
core   +1 more source

Principles and Practice Guidelines of Microbiota Medicine: Statements From the CHINAGUT Conference

Microbiota Medicine Research, EarlyView.
The 2025 CHINAGUT Conference convened a panel of 48 clinicians from 39 hospitals in 5 countries to develop 15 key statements, aimed at providing clinicians, educators, and healthcare administrators with a comprehensive framework to advance education, clinical practice, research, and public popularization in microbiota medicine.
Faming Zhang, Zheshun Pi, Sunny Hei Wong, Vineet Ahuja, Serena Porcari, Dai Ishikawa, Hailong Cao, Linlin Chen, Ning Chen, Xiong Chen, Bota Cui, Xiao Ding, Xingxiang He, Jia Hu, Jiang Jin, Ji Li, Weiwei Liao, Jingmei Liu, Ling Liu, Yanyan Liu, Yaping Liu, Yu Liu, Chen Lu, Gaochen Lu, Muhan Lv, Xiangjun Meng, Yongzhan Nie, Qian Ren, Lixuan Sang, Xin Sun, Yang Sun, Hongliang Tian, Baohong Wang, Honggang Wang, Liangjing Wang, Xin Wang, Weihong Wang, Zheyu Wang, Yanling Wei, Quan Wen, Lihao Wu, Xia Wu, Lijing Xiong, Guoliang Ye, Bo Yi, You Yu, Yue Zeng, Huihong Zhai, Ting Zhang, Zulun Zhang, Li Zhou, Li Zhu, Kaichun Wu   +52 more
wiley   +1 more source

Pathobiont-induced suppressive immune imprints thwart T cell vaccine responses [PDF]

Nature Communications
AbstractPathobionts have evolved many strategies to coexist with the host, but how immune evasion mechanisms contribute to the difficulty of developing vaccines against pathobionts is unclear. Meanwhile, Staphylococcus aureus (SA) has resisted human vaccine development to date.
Irshad Ahmed Hajam, Chih-Ming Tsai, Cesia Gonzalez, Juan Raphael Caldera, María Lázaro Díez, Xin Du, April Aralar, Brian Lin, William Duong, George Y. Liu   +9 more
openaire   +4 more sources

Biochemical characterization of the Escherichia coli surfaceome: a focus on type I fimbriae and flagella

Frontiers in Microbiology
The Escherichia coli surfaceome consists mainly of the large surface organelles expressed by the organism to navigate and interact with the surrounding environment. The current study focuses on type I fimbriae and flagella.
Devon W. Kavanaugh, Adeline Sivignon, Yannick Rossez, Zina Chouit, Christophe Chambon, Christophe Chambon, Louane Béal, Mathilde Bonnet, Michel Hébraud, Michel Hébraud, Yann Guérardel, Hang Thi Thu Nguyen, Nicolas Barnich   +12 more
doaj   +1 more source

How holobionts get sick—toward a unifying scheme of disease

Microbiome, 2017
All humans, animals, and plants are holobionts. Holobionts comprise the host and a myriad of interacting microorganisms—the microbiota. The hologenome encompasses the genome of the host plus the composite of all microbial genomes (the microbiome).
Silvio D. Pitlik, Omry Koren
doaj   +1 more source

Intra‐Tissue Bacteriome and Cellular Profiles in Periodontal Granulation Tissue From Osseous Defects and Extraction Sockets

Journal of Clinical Periodontology, EarlyView.
ABSTRACT Aim To investigate the intra‐tissue bacteriome and cell profiles within periodontal granulation tissue (PGT) for exploring the biological essence and translational potentials. Materials and Methods PGT samples were collected from 49 patients with severe periodontitis—including those from osseous defects (GT) during periodontal surgery ...
Tianfan Cheng, Tianle Li, Tsz Yung Wong, Beibei Chen, Chongshan Liao, Xun Ding, Hui Chen, Wei Qiao, George Pelekos, Lijian Jin   +9 more
wiley   +1 more source

Fecal microbiota transplant rescues mice from human pathogen mediated sepsis by restoring systemic immunity. [PDF]

, 2020
Death due to sepsis remains a persistent threat to critically ill patients confined to the intensive care unit and is characterized by colonization with multi-drug-resistant healthcare-associated pathogens.
Alverdy, John C, Antonopoulos, Dionysios A, Barreiro, Luis B, Bouziat, Romain, Christley, Scott, DeFazio, Jennifer R, Ernest, Jordan D, Fleming, Irma D, Gilbert, Jack A, Harris, Katharine G, Hyoju, Sanjiv K, Jabri, Bana, Keskey, Robert, Khodarev, Nikolai N, Kim, Sangman M, Krezalek, Monika A, Malik, Ankit, Ranoa, Diana R, Sangani, Kishan, Sangwan, Naseer, Shakhsheer, Baddr A, Weichselbaum, Ralph R, Wiegerinck, Mara, Zaborin, Alexander, Zaborina, Olga   +24 more
core