Results 131 to 140 of about 6,734 (227)
Diet–pathobiont interplay in health and inflammatory bowel disease
The intestinal microbiota plays a crucial role in maintaining host health by participating in various beneficial functions. However, under certain conditions, it can contribute to the development of inflammatory bowel disease (IBD) and other chronic inflammatory conditions.
Rytter, Héloïse +2 more
openaire +2 more sources
Crohn's disease (CD) is a chronic inflammatory condition of diverse etiology. Exposure to foodborne pathogens causing acute gastroenteritis produces a long-term risk of CD well into the post-infectious period but the mechanistic basis for this ongoing ...
Cherrie L Small +4 more
doaj +1 more source
Novel and emerging antimicrobial strategies in the management of oral infections
Abstract Background Antibiotics marked a pivotal turning point in human civilization, enhancing social interactions and extending human life expectancy. In addition to their success in treating systemic infectious diseases, they have significantly improved periodontal treatment outcomes as an adjunct therapy.
Ozge Unlu, Nil Yakar, Alpdogan Kantarci
wiley +1 more source
Le pathobionte Escherichia coli adhérent et invasif (AIEC) a été identifié avec une prévalence plus élevée chez les patients atteints de maladies inflammatoires chroniques de l'intestin (MICI). Les AIEC sont définis par leur capacité à (i) envahir les cellules épithéliales intestinales, (ii) survivre dans les macrophages (iii) sans marqueur génétique ...
openaire +1 more source
Abstract Cathelicidins are evolutionarily conserved host defence peptides known for their dual antimicrobial and immunomodulatory functions. Among them, LL‐37 in humans and CRAMP in rodents have emerged as crucial regulators of both mucosal immunity and CNS inflammation.
Mehrdad Nourizadeh +6 more
wiley +1 more source
Early adversity and the comorbidity between metabolic disease and psychopathology
Abstract figure legend Hierarchical diagram representing the interplay between the genetic background and early life adversities and its effect on multiple physiological processes that ultimately impact on the risk for the comorbdity between psychopathology and cardiometabolic disorders.
Ameyalli Gómez‐Ilescas +1 more
wiley +1 more source
Vagus nerve stimulation (VNS) effects span central and peripheral organ systems through diverse mechanistic pathways. This comprehensive review provides a unified synthesis of these mechanisms across neurological, cardiovascular, immunological, metabolic, and gastrointestinal domains, filling a critical gap and serving as a foundational resource for ...
Yifeng Bu +11 more
wiley +1 more source
BackgroundAntibiotics have profound and lasting effects on the lower intestinal (gut) microbiome that can both promote resistance and increase susceptibility to colonization and infection; knowledge of these changes is important to the prevention and ...
core
We report optimization of the Treponema denticola shuttle plasmid system by minimizing its size and by characterizing an array of promoter‐gene constructs for genetic complementation, including the first use in Treponema of a Tet‐inducible system for controlled expression of potentially toxic genes.
M. Paula Goetting‐Minesky +8 more
wiley +1 more source
Description: This review synthesizes groundbreaking advances in the gut‐liver axis for MASLD management. It details mechanistic pathways from transkingdom dysbiosis to liver pathology, integrating AI‐driven diagnostics and host genetics (PNPLA3). The framework transitions from broad microbial restoration to precision medicine, showcasing targeted ...
Shaoliang Zhu +8 more
wiley +1 more source

