Results 131 to 140 of about 6,734 (227)

Diet–pathobiont interplay in health and inflammatory bowel disease

open access: yesTrends in Microbiology
The intestinal microbiota plays a crucial role in maintaining host health by participating in various beneficial functions. However, under certain conditions, it can contribute to the development of inflammatory bowel disease (IBD) and other chronic inflammatory conditions.
Rytter, Héloïse   +2 more
openaire   +2 more sources

Acute Infectious Gastroenteritis Potentiates a Crohn's Disease Pathobiont to Fuel Ongoing Inflammation in the Post-Infectious Period.

open access: yesPLoS Pathogens, 2016
Crohn's disease (CD) is a chronic inflammatory condition of diverse etiology. Exposure to foodborne pathogens causing acute gastroenteritis produces a long-term risk of CD well into the post-infectious period but the mechanistic basis for this ongoing ...
Cherrie L Small   +4 more
doaj   +1 more source

Novel and emerging antimicrobial strategies in the management of oral infections

open access: yesPeriodontology 2000, EarlyView.
Abstract Background Antibiotics marked a pivotal turning point in human civilization, enhancing social interactions and extending human life expectancy. In addition to their success in treating systemic infectious diseases, they have significantly improved periodontal treatment outcomes as an adjunct therapy.
Ozge Unlu, Nil Yakar, Alpdogan Kantarci
wiley   +1 more source

Innovative functional characterization of the pro-inflammatory pathobiont Escherichia coli adherent and invasive pathobiont (AIEC).

open access: yes, 2023
Le pathobionte Escherichia coli adhérent et invasif (AIEC) a été identifié avec une prévalence plus élevée chez les patients atteints de maladies inflammatoires chroniques de l'intestin (MICI). Les AIEC sont définis par leur capacité à (i) envahir les cellules épithéliales intestinales, (ii) survivre dans les macrophages (iii) sans marqueur génétique ...
openaire   +1 more source

Immunomodulatory effects of cathelicidin in the gut–brain axis: A novel link between mucosal immunity and neuroinflammation

open access: yesExperimental Physiology, EarlyView.
Abstract Cathelicidins are evolutionarily conserved host defence peptides known for their dual antimicrobial and immunomodulatory functions. Among them, LL‐37 in humans and CRAMP in rodents have emerged as crucial regulators of both mucosal immunity and CNS inflammation.
Mehrdad Nourizadeh   +6 more
wiley   +1 more source

Early adversity and the comorbidity between metabolic disease and psychopathology

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Hierarchical diagram representing the interplay between the genetic background and early life adversities and its effect on multiple physiological processes that ultimately impact on the risk for the comorbdity between psychopathology and cardiometabolic disorders.
Ameyalli Gómez‐Ilescas   +1 more
wiley   +1 more source

A Review of Vagus Nerve Stimulation for Disease: Comprehensive Theory and Evidence for Mechanisms of Action

open access: yesComprehensive Physiology, Volume 16, Issue 2, April 2026.
Vagus nerve stimulation (VNS) effects span central and peripheral organ systems through diverse mechanistic pathways. This comprehensive review provides a unified synthesis of these mechanisms across neurological, cardiovascular, immunological, metabolic, and gastrointestinal domains, filling a critical gap and serving as a foundational resource for ...
Yifeng Bu   +11 more
wiley   +1 more source

J Travel Med [PDF]

open access: yes
BackgroundAntibiotics have profound and lasting effects on the lower intestinal (gut) microbiome that can both promote resistance and increase susceptibility to colonization and infection; knowledge of these changes is important to the prevention and ...

core  

Expanded Functional Characterization and Optimization of Protein Expression in Treponema denticola Shuttle Plasmids

open access: yesMolecular Oral Microbiology, Volume 41, Issue 2, Page 69-84, April 2026.
We report optimization of the Treponema denticola shuttle plasmid system by minimizing its size and by characterizing an array of promoter‐gene constructs for genetic complementation, including the first use in Treponema of a Tet‐inducible system for controlled expression of potentially toxic genes.
M. Paula Goetting‐Minesky   +8 more
wiley   +1 more source

The Gut‐Liver Axis in Metabolic Dysfunction‐Associated Steatotic Liver Disease: From Mechanistic Insights to Precision Therapeutics

open access: yesThe FASEB Journal, Volume 40, Issue 6, 31 March 2026.
Description: This review synthesizes groundbreaking advances in the gut‐liver axis for MASLD management. It details mechanistic pathways from transkingdom dysbiosis to liver pathology, integrating AI‐driven diagnostics and host genetics (PNPLA3). The framework transitions from broad microbial restoration to precision medicine, showcasing targeted ...
Shaoliang Zhu   +8 more
wiley   +1 more source

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