Results 11 to 20 of about 6,734 (227)

Dysbiosis by neutralizing commensal mediated inhibition of pathobionts [PDF]

Scientific Reports, 2016
Dysbiosis in the periodontal microbiota is associated with the development of periodontal diseases. Little is known about the initiation of dysbiosis.
Bernaerts, Kristel, Boon, Nico, Hernandez Sanabria, Emma, Herrero, Esteban Rodriguez, Quirynen, Marc, Slomka, Vera, Teughels, Wim   +6 more
core   +11 more sources

Putative Pathobionts in HLA-B27-Associated Spondyloarthropathy [PDF]

Frontiers in Immunology, 2021
Spondyloarthritis (SpA) is a group of immune mediated inflammatory diseases with a strong association to the major histocompatibility (MHC) class I molecule, HLA-B27. Although the association between HLA-B27 and AS has been known for almost 50 years, the
Tejpal Gill, James T. Rosenbaum, James T. Rosenbaum   +2 more
doaj   +3 more sources

When Pathobiont-Carbohydrate Interaction Turns Bittersweet! [PDF]

Cellular and Molecular Gastroenterology and Hepatology, 2021
Editorial Material ; International ...
Nicolas Barnich, Benoit Chassaing
doaj   +4 more sources

Keystone pathobionts associated with colorectal cancer promote oncogenic reprograming.

PLoS ONE, 2023
Fusobacterium nucleatum (Fn) and enterotoxigenic Bacteroides fragilis (ETBF) are two pathobionts consistently enriched in the gut microbiomes of patients with colorectal cancer (CRC) compared to healthy counterparts and frequently observed for their ...
Josh Jones, Qiaojuan Shi, Rahul R Nath, Ilana L Brito   +3 more
doaj   +4 more sources

Pathobiont-driven antibody sialylation through IL-10 undermines vaccination

The Journal of Clinical Investigation
The pathobiont Staphylococcus aureus (Sa) induces nonprotective antibody imprints that underlie ineffective staphylococcal vaccination. However, the mechanism by which Sa modifies antibody activity is not clear.
Chih-Ming Tsai, Irshad A. Hajam, J.R. Caldera, Austin W.T. Chiang, Cesia Gonzalez, Xin Du, Biswa Choudhruy, Haining Li, Emi Suzuki, Fatemeh Askarian, Ty’Tianna Clark, Brian Lin, Igor H. Wierzbicki, Angelica M. Riestra, Douglas J. Conrad, David J. Gonzalez, Victor Nizet, Nathan E. Lewis, George Y. Liu   +18 more
doaj   +5 more sources

Phages infecting the pathobiont <i>Escherichia coli</i> LF82. [PDF]

Microbiol Resour Announc
ABSTRACT Escherichia coli LF82 is a gut pathobiont commonly found in Crohn’s disease patients and a candidate for phage therapy. We report isolation of lytic phages able to infect LF82, with 19 unique genome sequences falling into four species clusters.
Steczynska JP, Ringholz MV, Wannemuehler MJ, Peters NT, Williams KP.   +4 more
europepmc   +3 more sources

Neisseria species as pathobionts in bronchiectasis

Cell Host & Microbe, 2022
Introduction : Le rôle des espèces de Neisseria dans la bronchectasie est inconnu. Méthodes : Le séquençage des bactériomes des échantillons de voies respiratoires de la cohorte de la bronchectasie asiatique et européenne appariée (CAMEB) (n=225) a été effectué pour évaluer les corrélats cliniques de la maladie associée à Neisseria spp.
Liang Li, Micheál Mac Aogáin, Tengfei Xu, Tavleen Kaur Jaggi, Louisa Chan, Jing Qu, Lan Wei, Shumin Liao, Hong Sheng Cheng, Holly R. Keir, Alison Dicker, Kai Sen Tan, Yun Wang, Mariko Siyue Koh, Thun How Ong, Albert Yick Hou Lim, John Abisheganaden, Teck Boon Low, Tidi Hassan, Xiang Long, Peter Wark, Brian Oliver, Daniela I. Drautz–Moses, Stephan C. Schuster, Nguan Soon Tan, Mingliang Fang, James D. Chalmers, Sanjay H. Chotirmall   +27 more
openaire   +4 more sources

Label or Concept – What Is a Pathobiont? [PDF]

Trends in Microbiology, 2020
An increasing number of microorganisms are classified as 'pathobionts' (i.e., organisms that can cause harm under certain circumstances) but there exist no universally used criteria for this definition. In particular, the term is often used for categorizing disease-associated taxa without proof of 'causality'.
Lara, Jochum, Bärbel, Stecher
openaire   +2 more sources

Oral biofilms exposure to chlorhexidine results in altered microbial composition and metabolic profile [PDF]

, 2020
Oral diseases (e.g., dental caries, periodontitis) are developed when the healthy oral microbiome is imbalanced allowing the increase of pathobiont strains.
Boon, Nico, Chatzigiannidou, Ioanna, Teughels, Wim, Van de Wiele, Tom   +3 more
core   +2 more sources

A shared mucosal gut microbiota signature in primary sclerosing cholangitis before and after liver transplantation

Hepatology, EarlyView., 2022
In this study of the gut mucosal microbiota in primary sclerosing cholangitis (PSC), we found consistent microbiota features associated with PSC and recurrent PSC, PSC with inflammatory bowel disease and a persistent gut dysbiosis after liver transplantation Abstract Background and Aims Several characteristic features of the fecal microbiota have been ...
Mikal Jacob Hole, Kristin Kaasen Jørgensen, Kristian Holm, Peder R. Braadland, Malin Holm Meyer‐Myklestad, Asle Wilhelm Medhus, Dag Henrik Reikvam, Alexandra Götz, Krzysztof Grzyb, Kirsten Muri Boberg, Tom Hemming Karlsen, Martin Kummen, Johannes R. Hov   +12 more
wiley   +1 more source