Results 1 to 10 of about 1,726,520 (358)

Clinical Metagenomic Next-Generation Sequencing for Pathogen Detection

Annual Review of Pathology: Mechanisms of Disease, 2019
Nearly all infectious agents contain DNA or RNA genomes, making sequencing an attractive approach for pathogen detection. The cost of high-throughput or next-generation sequencing has been reduced by several orders of magnitude since its advent in 2004 ...
Wei Gu, Steve Miller, Charles Y Chiu
exaly   +2 more sources

Urinary tract infections: microbial pathogenesis, host–pathogen interactions and new treatment strategies

Nature Reviews Microbiology, 2020
Scott J Hultgren
exaly   +2 more sources

Plant immunity: towards an integrated view of plant–pathogen interactions

Nature Reviews Genetics, 2010
Peter N Dodds
exaly   +2 more sources

Rapid pathogen detection by metagenomic next-generation sequencing of infected body fluids

Nature Medicine, 2020
Wei Gu, Xianding Deng, Doug Stryke
exaly   +2 more sources

Pseudomonas aeruginosa: An Audacious Pathogen with an Adaptable Arsenal of Virulence Factors

International Journal of Molecular Sciences, 2021
Pseudomonas aeruginosa is a dominant pathogen in people with cystic fibrosis (CF) contributing to morbidity and mortality. Its tremendous ability to adapt greatly facilitates its capacity to cause chronic infections.
Irene Jurado-Martín, Maite Sainz-Mejías, S. McClean   +2 more
semanticscholar   +1 more source

Staphylococcus epidermidis — the 'accidental' pathogen

Nature Reviews Microbiology, 2009
Michael Otto
exaly   +2 more sources

MiR-279-3p regulates deltamethrin resistance through CYP325BB1 in Culex pipiens pallens

Parasites & Vectors, 2021
Background The overuse of insecticides to control insect vectors has promoted extensive insecticide resistance in mosquitoes. In this study, the functions of microRNA (miR)-279-3p and its target CYP325BB1 in the regulation of deltamethrin resistance in ...
Xixi Li, Shengli Hu, Hongbo Zhang, Haitao Yin, Huan Wang, Dan Zhou, Yan Sun, Lei Ma, Bo Shen, Changliang Zhu   +9 more
doaj   +1 more source

MiR-4448 is involved in deltamethrin resistance by targeting CYP4H31 in Culex pipiens pallens

Parasites & Vectors, 2021
Background Culex pipiens (Cx. pipiens) complex, which acts as a vector of viruses and is widespread and abundant worldwide, including West Nile virus, Japanese encephalitis virus, and Sindbis virus, can cause serious vector-borne diseases affecting human
Xixi Li, Shengli Hu, Haitao Yin, Hongbo Zhang, Dan Zhou, Yan Sun, Lei Ma, Bo Shen, Changliang Zhu   +8 more
doaj   +1 more source

Therapeutic potential of fucoidan in the reduction of hepatic pathology in murine schistosomiasis japonica

Parasites & Vectors, 2020
Background Hepatic granuloma formation and fibrosis as the consequence of tissue entrapped eggs produced by female schistosomes characterize the pathology of Schistosoma japonicum infection.
Xueqi Bai, Maining Li, Xinyue Wang, Hao Chang, Yangyue Ni, Chen Li, Kaiyue He, Huiquan Wang, Yuxuan Yang, Tian Tian, Min Hou, Minjun Ji, Zhipeng Xu   +12 more
doaj   +1 more source

Physiological characterization of chitin synthase A responsible for the biosynthesis of cuticle chitin in Culex pipiens pallens (Diptera: Culicidae)

Parasites & Vectors, 2021
Background The pathogens transmitted by mosquitoes to humans and animals cause several emerging and resurgent infectious diseases. Increasing insecticide resistance requires rational action to control the target vector population. Chitin is indispensable
Xiaoshan Yang, Yang Xu, Qi Yin, Hongbo Zhang, Haitao Yin, Yan Sun, Lei Ma, Dan Zhou, Bo Shen   +8 more
doaj   +1 more source