Results 31 to 40 of about 256,778 (292)

Stimulation of Mytilus galloprovincialis Hemocytes With Different Immune Challenges Induces Differential Transcriptomic, miRNomic, and Functional Responses

open access: yesFrontiers in Immunology, 2020
Mediterranean mussels (Mytilus galloprovincialis) are marine bivalve molluscs with high resilience to biotic and abiotic stress. This resilience is one of the reasons why this species is such an interesting model for studying processes such as the immune
Rebeca Moreira   +7 more
doaj   +1 more source

Microbial pathogens induce neurodegeneration in Alzheimer’s disease mice: protection by microglial regulation

open access: yesJournal of Neuroinflammation, 2022
Background Neurodegeneration is considered the consequence of misfolded proteins’ deposition. Little is known about external environmental effects on the neurodegenerative process.
Tal Ganz   +6 more
doaj   +1 more source

Central Role for MyD88 in the Responses of Microglia to Pathogen-Associated Molecular Patterns [PDF]

open access: yesThe Journal of Immunology, 2006
Abstract Microglia, the innate immune effector cells of the CNS parenchyma, express TLR that recognize conserved motifs of microorganisms referred to as pathogen-associated molecular patterns (PAMP). All TLRs identified to date, with the exception of TLR3, use a common adaptor protein, MyD88, to transduce activation signals. Recently, we
Nilufer, Esen, Tammy, Kielian
openaire   +2 more sources

Suppression of CYP1 members of the AHR response by pathogen-associated molecular patterns [PDF]

open access: yesJournal of Leukocyte Biology, 2017
AbstractThe aryl hydrocarbon receptor (AHR) is a ligand-activated transcription factor that triggers a broad response, which includes the regulation of proinflammatory cytokine production by monocytes and macrophages. AHR is negatively regulated by a set of genes that it transcriptionally activates, including the AHR repressor (Ahrr) and the cytochrome
Adam G, Peres   +3 more
openaire   +2 more sources

The molecular basis of host specialization in bean pathovars of Pseudomonas syringae [PDF]

open access: yes, 2012
Biotrophic phytopathogens are typically limited to their adapted host range. In recent decades, investigations have teased apart the general molecular basis of intraspecific variation for innate immunity of plants, typically involving receptor ...
Baltrus, David A.   +7 more
core   +1 more source

Case Report: Kawasaki disease associated with acute generalized exanthematous pustulosis secondary to carbocysteine

open access: yesFrontiers in Pediatrics
Acute generalized exanthematous pustulosis (AGEP) is an uncommon eruption characterized by sterile pustules on an erythematous background, which is usually associated with drugs. AGEP is described as a self-limiting disease with favorable prognosis.
Takashi Furuta   +5 more
doaj   +1 more source

Current and emerging analytical technologies for analyzing chitin-protein binding interactions

open access: yesReviews in Analytical Chemistry, 2013
Chitin, a small organic molecule commonly found in fungal cell walls and insect exoskeletons, has the ability to elicit an immune response in plants by binding to specific membrane-bound receptors. Understanding how plants detect and fend off deleterious
Dahmen Jeremy L.   +2 more
doaj   +1 more source

Cognitive Alterations in Old Mice Are Associated with Intestinal Barrier Dysfunction and Induced Toll-like Receptor 2 and 4 Signaling in Different Brain Regions

open access: yesCells, 2023
Emerging evidence implicate the ‘microbiota–gut–brain axis’ in cognitive aging and neuroinflammation; however, underlying mechanisms still remain to be elucidated.
Annette Brandt   +9 more
doaj   +1 more source

Enhancing acute inflammatory and sepsis treatment: superiority of membrane receptor blockade

open access: yesFrontiers in Immunology
Conditions such as acute pancreatitis, ulcerative colitis, delayed graft function and infections caused by a variety of microorganisms, including gram-positive and gram-negative organisms, increase the risk of sepsis and therefore mortality.
Seok-Jun Mun   +10 more
doaj   +1 more source

The Plant – Pathogen Interactions

open access: yesMicrobiology Indonesia, 2010
Interaction between plants and their pathogens is complex, involving multifaceted recognition of pathogens by the plants and, on the other hand, subtle evasion from the pathogens.
CAHYA PRIHATNA
doaj   +1 more source

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