Results 31 to 40 of about 258,381 (291)

Molecular epidemiology of Mycobacterium africanum in Ghana [PDF]

, 2016
BACKGROUND: Mycobacterium africanum comprises two phylogenetic lineages within the M. tuberculosis complex (MTBC) and is an important cause of human tuberculosis (TB) in West Africa. The reasons for this geographic restriction of M.
Forson, Audrey, Yeboah-Manu, Dorothy, Esther Sarpong, Otchere, Isaac Darko, Borrell, Sonia, Clement Laryea, Gagneux, Sebastien, Frank Bonsu, Osei-Wusu, Stephen, Akosua Baddoo, Stephen Osei-Wusu, Ahorlu, Collins, Kwadwo A. Koram, Sarpong, Esther, Adwoa Asante-Poku, Collins Ahorlu, Audrey Forson, Laryea, Clement, Isaac Darko Otchere, Sebastien Gagneux, Bonsu, Frank, Hattendorf, Jan, Dorothy Yeboah-Manu, Sonia Borrell, Asante-Poku, Adwoa, Koram, Kwadwo A., Baddoo, Akosua, Jan Hattendorf   +27 more
core   +1 more source

Intestinal inflammation responds to microbial tissue load independent of pathogen/non-pathogen discrimination [PDF]

, 2012
The intestinal immune system mounts inflammatory responses to pathogens but tolerates harmless commensal microbiota. Various mechanisms for pathogen/non-pathogen discrimination have been proposed but their general relevance for inflammation control is ...
Dirk Bumann (126124), Dirk Bumann, Yvonne Willer (126110), Willer, Yvonne, Willer Yvonne, Müller, Beatrice, Bumann, D., Yvonne Willer, Willer, Y., Beatrice Müller, Müller Beatrice, Müller, B., Bumann, Dirk, Bumann Dirk, Beatrice Müller (166158)   +14 more
core   +1 more source

MCL and Mincle: C-Type Lectin Receptors That Sense Damaged Self and Pathogen-Associated Molecular Patterns. [PDF]

Front Immunol, 2014
MCL (macrophage C-type lectin) and mincle (macrophage inducible C-type lectin) comprise part of an extensive repertoire of pattern recognition receptors with the ability to sense damage associated and pathogen associated molecular patterns.
Richardson MB, Williams SJ.
europepmc   +3 more sources

The plasmodesmal protein PDLP1 localises to haustoria-associated membranes during downy mildew infection and regulates callose deposition [PDF]

, 2014
The downy mildew pathogen Hyaloperonospora arabidopsidis (Hpa) is a filamentous oomycete that invades plant cells via sophisticated but poorly understood structures called haustoria.
Wirthmueller, Lennart, Jones, Jonathan D. G., Piquerez, Sophie J. M., Robatzek, Silke, Marie-Cécile Caillaud, Caillaud, Marie-Cécile, Jonathan D G Jones, Sklenar, Jan, Faulkner, Christine, Sophie J. M. Piquerez (198592), Kim Findlay (232058), Marie-Cécile Caillaud (3212142), Lennart Wirthmueller (646107), Silke Robatzek, Findlay, Kim, Jan Sklenar (142122), Jonathan D. G. Jones (198635), Jones, Alexandra M., Lennart Wirthmueller, Christine Faulkner, Alexandra M. E. Jones (50010), Silke Robatzek (242498), Kim Findlay, Alexandra M E Jones, Christine Faulkner (224195), Jan Sklenar, Sophie J M Piquerez   +26 more
core   +1 more source

Pathogen-associated molecular patterns on biomaterials: a paradigm for engineering new vaccines [PDF]

Trends in Biotechnology, 2011
Vaccine development has progressed significantly and has moved from whole microorganisms to subunit vaccines that contain only their antigenic proteins. Subunit vaccines are often less immunogenic than whole pathogens; therefore, adjuvants must amplify the immune response, ideally establishing both innate and adaptive immunity.
Stacey L, Demento, Alyssa L, Siefert, Arunima, Bandyopadhyay, Fiona A, Sharp, Tarek M, Fahmy   +4 more
openaire   +2 more sources

Cross Kingdom Immunity: The Role of Immune Receptors and Downstream Signaling in Animal and Plant Cell Death

Frontiers in Immunology, 2021
Both plants and animals are endowed with sophisticated innate immune systems to combat microbial attack. In these multicellular eukaryotes, innate immunity implies the presence of cell surface receptors and intracellular receptors able to detect danger ...
Thibault Roudaire, Marie-Claire Héloir, David Wendehenne, Aymeric Zadoroznyj, Aymeric Zadoroznyj, Laurence Dubrez, Laurence Dubrez, Benoit Poinssot   +7 more
doaj   +1 more source

Suppression of CYP1 members of the AHR response by pathogen-associated molecular patterns [PDF]

Journal of Leukocyte Biology, 2017
AbstractThe aryl hydrocarbon receptor (AHR) is a ligand-activated transcription factor that triggers a broad response, which includes the regulation of proinflammatory cytokine production by monocytes and macrophages. AHR is negatively regulated by a set of genes that it transcriptionally activates, including the AHR repressor (Ahrr) and the cytochrome
Adam G, Peres, Robert, Zamboni, Irah L, King, Joaquín, Madrenas   +3 more
openaire   +2 more sources

Evidence for directional selection at a novel major histocompatibility class I marker in wild common frogs (Rana temporaria) exposed to a viral pathogen (Ranavirus). [PDF]

, 2009
(c) 2009 Teacher et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are ...
Trenton W J Garner, Richard A. Nichols, Trenton W. J. Garner, Garner, TWJ, Teacher, AGF, Amber G F Teacher, Teacher Amber G. F., Richard A Nichols, Garner Trenton W. J., Amber G. F. Teacher, Nichols, RA, Nichols Richard A.   +11 more
core   +1 more source

Stimulation of Mytilus galloprovincialis Hemocytes With Different Immune Challenges Induces Differential Transcriptomic, miRNomic, and Functional Responses

Frontiers in Immunology, 2020
Mediterranean mussels (Mytilus galloprovincialis) are marine bivalve molluscs with high resilience to biotic and abiotic stress. This resilience is one of the reasons why this species is such an interesting model for studying processes such as the immune
Rebeca Moreira, Alejandro Romero, Magalí Rey-Campos, Patricia Pereiro, Umberto Rosani, Umberto Rosani, Beatriz Novoa, Antonio Figueras   +7 more
doaj   +1 more source

Microbial pathogens induce neurodegeneration in Alzheimer’s disease mice: protection by microglial regulation

Journal of Neuroinflammation, 2022
Background Neurodegeneration is considered the consequence of misfolded proteins’ deposition. Little is known about external environmental effects on the neurodegenerative process.
Tal Ganz, Nina Fainstein, Amit Elad, Marva Lachish, Smadar Goldfarb, Ofira Einstein, Tamir Ben-Hur   +6 more
doaj   +1 more source