Results 51 to 60 of about 258,381 (291)

Chromatin-Associated Molecular Patterns (CAMPs) in sepsis

Cell Death and Disease, 2022
Several molecular patterns have been identified that recognize pattern recognition receptors. Pathogen-associated molecular patterns (PAMPs) and damage-associated molecular patterns (DAMPs) are commonly used terminologies to classify molecules ...
Colleen P. Nofi, Ping Wang, Monowar Aziz
doaj   +1 more source

Immunogenic cell death: The cornerstone of oncolytic viro-immunotherapy

Frontiers in Immunology, 2023
According to the World Health Organization, cancer is one of the leading global health concerns, causing nearly 10 million deaths in 2020. While classical chemotherapeutics produce strong cytotoxicity on cancer cells, they carry limitations of drug ...
Lalitha Palanivelu, Ching-Hsuan Liu, Ching-Hsuan Liu, Ching-Hsuan Liu, Liang-Tzung Lin, Liang-Tzung Lin   +5 more
doaj   +1 more source

Viral Capsid Is a Pathogen-Associated Molecular Pattern in Adenovirus Keratitis

PLoS Pathogens, 2010
Human adenovirus (HAdV) infection of the human eye, in particular serotypes 8, 19 and 37, induces the formation of corneal subepithelial leukocytic infiltrates. Using a unique mouse model of adenovirus keratitis, we studied the role of various virus-associated molecular patterns in subsequent innate immune responses of resident corneal cells to HAdV-37
Chintakuntlawar, Ashish V., Zhou, Xiaohong, Rajaiya, Jaya, Chodosh, James   +3 more
openaire   +6 more sources

Complete genome sequence of the fire blight pathogen Erwinia pyrifoliae DSM 12163(T) and comparative genomic insights into plant pathogenicity [PDF]

, 2010
Smits THM, Jaenicke S, Rezzonico F, et al. Complete genome sequence of the fire blight pathogen Erwinia pyrifoliae DSM 12163(T) and comparative genomic insights into plant pathogenicity. BMC Genomics.
Smits, Theo H. M., Kamber, Tim, Sebastian Jaenicke, Goesmann, Alexander ; https://orcid.org/, Theo HM Smits, Fabio Rezzonico, Rezzonico, Fabio, Jaenicke, Sebastian, Frey, Jürg E, Duffy, Brion, Tim Kamber, Jürg E Frey, Brion Duffy, Alexander Goesmann   +13 more
core   +2 more sources

Ovarian Sex Cord Stromal Tumors in Children and Adolescents—The European Standard Clinical Practice Recommendations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT As part of the European Cooperative Study Group for Paediatric Rare Tumours initiative, we developed standard clinical practice guidelines for ovarian sex cord stromal tumors, based on comprehensive national and international cohort analyses, literature review, and a final expert consensus conference.
Dominik T. Schneider, Kris‐Ann Schultz, Nora Schnitzler, Michael Abele, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Ines B. Brecht, Maja Cesen, Andrea Ferrari, Michaela Kuhlen, Malgorzata A. Krawczyk, Ricardo Lopez‐Almaraz, Yves Reguerre, Calogero Virgone, Daniel Orbach   +15 more
wiley   +1 more source

Variation in resistance to multiple pathogen species:anther-smuts of Silene uniflora [PDF]

, 2012
The occurrence of multiple pathogen species on a shared host species is unexpected when they exploit the same micro-niche within the host. One explanation for such observations is the evolution of pathogen-specific resistances that segregate the host ...
Pedersen, Amy, Petit, Elsa, Erin, Chung, Antonovics, Janis, Hood, Michael E.   +4 more
core   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

When the infectious environment meets the AD brain

Molecular Neurodegeneration, 2022
Background The Amyloid theory of Alzheimer’s disease (AD) suggests that the deposition of Amyloid β (Aβ) in the brain triggers a chain of events, involving the deposition of phosphorylated Tau and other misfolded proteins, leading to neurodegeneration ...
Tal Ganz, Nina Fainstein, Tamir Ben-Hur
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Development of the immune response in pneumonia due to Staphylococcus aureus (part 1)

Zdorovʹe Rebenka, 2017
The literature review presents modern data on the pathogen-associated molecular structures of Staphylococcus aureus and its role in the occurrence of pneumonia: activation and modulation of the immune response, oxidative and metabolic stress, apoptosis ...
A.E. Abaturov, A.A. Nikulinа
doaj   +1 more source