Results 71 to 80 of about 256,778 (292)

Assay for Pathogen-Associated Molecular Pattern (PAMP)-Triggered Immunity (PTI) in Plants [PDF]

Journal of Visualized Experiments, 2009
To perceive potential pathogens in their environment, plants use pattern recognition receptors (PRRs) present on their plasma membranes. PRRs recognize conserved microbial features called pathogen-associated molecular patterns (PAMPs) and this detection leads to PAMP-triggered immunity (PTI), which effectively prevents colonization of plant tissues by ...
Chakravarthy, Suma, Velásquez, André C., Martin, Gregory B.   +2 more
openaire   +2 more sources

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

The Etiopathogenesis of Kawasaki Disease: Evolving Understanding of Diverse Triggers

Immunity, Inflammation and Disease
Background Kawasaki disease (KD) is a leading cause of acquired heart disease in children. Evidence suggests that microbial and nonmicrobial triggers for KD differ across geographical regions and environmental conditions.
Toshiro Hara, Yasunari Sakai
doaj   +1 more source

Neutral Genomic Microevolution of a Recently Emerged Pathogen, Salmonella enterica Serovar Agona [PDF]

, 2013
Salmonella enterica serovar Agona has caused multiple food-borne outbreaks of gastroenteritis since it was first isolated in 1952. We analyzed the genomes of 73 isolates from global sources, comparing five distinct outbreaks with sporadic infections as ...
Eva Litrup (404346), Murphy, Ronan, Fanning, S, Mark Achtman, Angela McCann (404345), Sylvain Brisse (87594), Brown, D, Zhou, Z, Cormican, Martin, Brisse, Sylvain, Mark Achtman (126786), Guttman, David S., Zhemin Zhou (157214), Ronan Murphy (404347), Brown, Derek, Litrup, Eva, Seamus Fanning (5651275), McCann, Angela, Brisse, S, David S. Guttman (131322), Achtman, Mark, McCann, A, Derek Brown (404349), Sylvain Brisse, Zhou, Zhemin, Litrup, E, Murphy, R, Angela McCann, Zhemin Zhou, David S Guttman, Martin Cormican, Guttman, DS, Eva Litrup, Ronan Murphy, Seamus Fanning, Derek Brown, Fanning, Seamus, Achtman, M, Cormican, M, Martin Cormican (404348)   +39 more
core   +1 more source

Adenovirus-mediated gene transfer of pathogen-associated molecular patterns for cancer immunotherapy [PDF]

Cancer Gene Therapy, 2008
The delivery of stimulatory signals to dendritic cells (DCs) in the tumor microenvironment could be an effective means to break tumor-induced tolerance. The work presented here evaluates the immunostimulatory properties of pathogen-associated molecular patterns (PAMPs), microbial molecules which bind Toll-like receptors and deliver activating signals ...
C, Tosch, M, Geist, C, Ledoux, C, Ziller-Remi, S, Paul, P, Erbs, N, Corvaia, P, Von Hoegen, J-M, Balloul, H, Haegel   +9 more
openaire   +2 more sources

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Comprehending toll-like receptors: pivotal element in the pathogenesis of sepsis and its complications

Frontiers in Immunology
Sepsis, a critical systemic inflammatory response syndrome elicited by pathogenic microorganisms, poses a significant challenge in clinical practice due to its rapid progression and potential for multi-organ failure.
Wei Wang, Shengtian Mu, Dongli Yan, Huan Qin, Zhen Zheng   +4 more
doaj   +1 more source

Molecular and proteomic analyses highlight the importance of ubiquitination for the stress resistance, metabolic adaptation, morphogenetic regulation and virulence of Candida albicans [PDF]

, 2011
Peer ...
Alistair J. P. Brown, Argo, Evelyn Ann, Michelle D. Leach, MacCallum, Donna Margaret, David A. Stead, Evelyn Argo, Donna M. MacCallum, Stead, David Andrew, Brown, Alistair James Petersen, Leach, Michelle Donna   +9 more
core   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

ADP heptose, a novel pathogen‐associated molecular pattern identified in Helicobacter pylori [PDF]

The FASEB Journal, 2019
ABSTRACT The gastric pathogen Helicobacter pylori activates the NF‐κB pathway in human epithelial cells via the recently discovered α‐kinase 1 TRAF‐interacting protein with forkhead‐associated domain (TIFA) axis.
Pfannkuch, L., Hurwitz, R., Traulsen, J., Sigulla, J., Poeschke, M., Matzner, L., Kosma, P., Schmid, M., Meyer, T.   +8 more
openaire   +3 more sources