Results 61 to 70 of about 258,381 (291)
DAMPs and Innate Immune Training
Frontiers in Immunology, 2021 The ability to remember a previous encounter with pathogens was long thought to be a key feature of the adaptive immune system enabling the host to mount a faster, more specific and more effective immune response upon the reencounter, reducing the ...
Elisa Jentho +3 more
doaj +1 more source
Pathogen Associated Molecular Patterns, Pattern Recognition Receptors and Pediatric Sepsis [PDF]
The Open Inflammation Journal, 2011 The mortality of septic shock in the pediatric population has improved over the last 2 decades with better supportive care however it still remains unacceptably high. Exaggerated inflammatory responses early in septic shock have been associated with poor outcomes.
openaire +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Usefulness of plasminogen activator inhibitor-1 as a predictive marker of mortality in sepsis
Journal of Intensive Care, 2017 Background Sepsis is one of the most significant causes of mortality in intensive care units. It indicates crosstalk between inflammation and coagulation.
Kota Hoshino +6 more
doaj +1 more source
NLRP3: Role in ischemia/reperfusion injuries
Frontiers in Immunology, 2022 NLR family pyrin domain containing 3 (NLRP3) is expressed in immune cells, especially in dendritic cells and macrophages and acts as a constituent of the inflammasome.
Soudeh Ghafouri-Fard +10 more
doaj +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
The role of pathogen-associated molecular patterns and islet-derived danger-associated molecular patterns in longevity of microencapsulated pancreatic islets [PDF]
, 2016 Immunoisolation of cells by encapsulation in semipermeable membranes has been proposed as a cure for many endocrine diseases where a minute-to-minute regulation of metabolites is a requirement such as in anemia, dwarfism, kidney and liver failure ...
Paredes Juárez, Genaro Alberto
core +5 more sources
Molecular Plant-Microbe Interactions, 2006 Nonspecific recognition of pathogen-derived general elicitors triggers the first line of plant basal defense, which in turn, preconditions the host towards resistance or susceptibility. To elucidate how basal defense responses influence the onset of Mla (
Rico A. Caldo +3 more
doaj +1 more source
Animals, 2022 The presence of β-mannans in feed can produce a futile and chronic immune stimulation in fattening pigs. In this trial, a 1-4-endo-D-β-mannanase was added to the feed (HC) during growth and fattening (0.03% of Hemicell HT) and physical performance and ...
Pedro Sánchez-Uribe +9 more
doaj +1 more source
Mycobacterium africanum is associated with patient ethnicity in Ghana [PDF]
, 2014 Mycobacterium africanum is a member of the Mycobacterium tuberculosis complex (MTBC) and an important cause of human tuberculosis in West Africa that is rarely observed elsewhere.
Yeboah-Manu, Dorothy +30 more
core +1 more source