The bug, the burden, and the biology: beyond host-centric phenotyping in sepsis. [PDF]
Kitsios GD, Baron RM.
europepmc +1 more source
A Non‐Host Pathogen Elicitor Induces Blast Resistance Mediated by OsNAC78‐Pir7b Module in Rice
ABSTRACT Plants exhibit broad‐spectrum and persistent resistance induced by non‐host pathogens. Previous studies have found that syringolin A secreted by Pseudomonas syringae pv. syringae can activate the expression of defense‐related gene Pir7b in non‐host rice, but the underlying mechanism remains ambiguous.
Yunjie Xie +11 more
wiley +1 more source
Deciphering Role of Endophytes in Plant Defences and Biotic Stress Resilience Across Families
ABSTRACT Plant families generate distinct repertoires of specialised metabolites that govern their biotic interactions. Endophytes strengthen host plant defence mechanisms and tolerance to biotic challenges by upregulating metabolite biosynthesis, modifying precursor compounds into more potent forms, or by directly synthesising analogous defence ...
S. Aneeqa Noor +4 more
wiley +1 more source
Subverting Host Defense from Within: Innate Immune Modulation by <i>Coxiella burnetii</i>. [PDF]
Busbee AO +3 more
europepmc +1 more source
Antibiotic‐mediated immune modulation in periodontitis
Abstract Periodontitis is a chronic inflammatory disease affecting the supporting structures of the teeth. Although initiated by dysbiotic microbial communities, its progression is largely driven by the host's uncontrolled inflammatory response. While antibiotics have conventionally been employed in periodontitis therapy for their antimicrobial ...
Lina J. Suárez +6 more
wiley +1 more source
Pyroptosis, A Double-Edged Sword in Respiratory Diseases: A Narrative Review. [PDF]
Yu C, Dai C, Zhu L.
europepmc +1 more source
The role of neutrophils in the pathophysiology of inflammatory bowel diseases
Abstract Objectives Inflammatory bowel disease (IBD) encompasses a spectrum of chronic disorders of the gastrointestinal tract, with a potential bidirectional relationship with periodontitis. Neutrophils are key regulators of immune‐inflammatory responses and play a major role in both diseases.
Joao Paulo Steffens +8 more
wiley +1 more source
Gut-derived bacterial extracellular vesicles: the microbial dark matter contributing to host inflammation and cardiometabolic disease. [PDF]
Oliver B +6 more
europepmc +1 more source
Histiocytes: Multifaceted Regulators of Health and Disease
ABSTRACT The mononuclear phagocyte system encompasses macrophages, dendritic cells (DCs), and monocytes. Tissue‐resident macrophages and dendritic cells arise during embryogenesis and are replenished either through self‐renewal or by monocytes during inflammation.
Erika J. Gruber
wiley +1 more source
Beyond pathogens: a narrative review of the immunological nexus of damage-associated molecular patterns and inflammasome activation in sterile AECOPD. [PDF]
Peng C +7 more
europepmc +1 more source

