Results 181 to 190 of about 44,783 (256)

Pathways of Protein Secretion in Prokaryotes and Eukaryotes: Molecular Mechanisms, Biological Functions, and Therapeutic Opportunities

open access: yesMedComm, Volume 7, Issue 6, June 2026.
This graphical abstract delineates noncanonical protein secretion systems across eukaryotes and prokaryotes. Eukaryotic UcPS covers four ER–Golgi bypass pathways, enabling rapid leaderless protein export via direct transmembrane translocation or vesicle‐mediated release.
Qiyuan Yang   +8 more
wiley   +1 more source

Circadian Immunity and Vascular Inflammation in Cardiovascular Disease Chronotherapy Windows: Time for a Re‐Assessment

open access: yesMed Research, Volume 2, Issue 2, Page 236-279, June 2026.
ABSTRACT Circadian rhythms orchestrate cardiovascular physiology by regulating immune and inflammatory pathways. Disruption of these rhythms profoundly alters vascular homeostasis, thereby promoting the onset and progression of cardiovascular diseases (CVD).
Tian Zhang   +22 more
wiley   +1 more source

Wheat Plasma Membrane Receptors: Orchestrating Immunity and Bridging to Crop Improvement. [PDF]

open access: yesCurr Issues Mol Biol
Khalil HB   +8 more
europepmc   +1 more source

Inflammation, Immunity, and Cardiovascular Diseases

open access: yesMed Research, Volume 2, Issue 2, Page 343-370, June 2026.
Cardiovascular stress signals (e.g., hemodynamic shear, oxidized lipids, and ischemia) act on endothelial and immune cells to activate and amplify inflammation through NF‐κB, the NLRP3 inflammasome, and JAK/STAT signaling, inducing proinflammatory cytokines/chemokines (IL‐6, IL‐1β, TNF‐α, and CCL2) and self‐amplifying circuits; clinically, inflammatory
Dezhi Guo   +8 more
wiley   +1 more source

Microbial SynComs as biocontrol tools: modulating plant immunity and future perspectives. [PDF]

open access: yesFront Microbiol
Gaur V   +5 more
europepmc   +1 more source

Oxidative Stress in the Tumor Immune Microenvironment: Mechanisms and Therapeutic Perspectives

open access: yesMedComm – Oncology, Volume 5, Issue 2, June 2026.
Oxidative stress is involved in several key processes in cancer, including redox regulation, DNA damage, post‐translational modifications, transcriptional regulation, epigenetic modifications, metabolic reprogramming, cell death, and immune modulation. These mechanisms collectively influence tumor progression, immune evasion, and therapeutic responses,
Zhen Wang   +14 more
wiley   +1 more source

Synergy between immune system and antibiotics drives infection control in mice. [PDF]

open access: yesFront Immunol
Padmakumari RG   +8 more
europepmc   +1 more source

Investigating the structural basis of surfactant protein D oligomerization: The crucial role of Cys15‐Cys15/Cys20‐Cys20 disulfide bond linkage

open access: yesProtein Science, Volume 35, Issue 6, June 2026.
Abstract Surfactant protein D (SP‐D) plays a vital role in innate immunity by recognizing and binding to glycans on the surfaces of various pathogens. The oligomerization of SP‐D into dodecameric structures enhances its pathogen‐binding and antiviral activities.
Deng Li, Mona S. Minkara
wiley   +1 more source

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