Results 21 to 30 of about 1,634,389 (309)

Global analysis of gene expression reveals mRNA superinduction is required for the inducible immune response to a bacterial pathogen. [PDF]

, 2017
The inducible innate immune response to infection requires a concerted process of gene expression that is regulated at multiple levels. Most global analyses of the innate immune response have focused on transcription induced by defined immunostimulatory ...
Barry, Kevin C, Ingolia, Nicholas T, Vance, Russell E   +2 more
core   +3 more sources

Absence of Batf3 results in reduced liver pathology in mice infected with Schistosoma japonicum

Parasites & Vectors, 2017
Background The involvement of CD8+T cells in schistosomiasis is being increasingly appreciated, but the underlying mechanism is not well defined. Results In this study, we showed that the absence of Batf3 alleviated liver damage in Batf3 −/− mice ...
Lin Chen, Donghui Zhang, Wenyue Zhang, Yuxiao Zhu, Min Hou, Bingya Yang, Zhipeng Xu, Minjun Ji, Guanling Wu   +8 more
doaj   +1 more source

Livestock abundance predicts vampire bat demography, immune profiles, and bacterial infection risk [PDF]

, 2018
Human activities create novel food resources that can alter wildlife–pathogen interactions. If resources amplify or dampen, pathogen transmission probably depends on both host ecology and pathogen biology, but studies that measure responses to ...
Altizer, Sonia, Becker, Daniel, Bentz, Alexandra B., Camus, Melinda S., Carrera, Jorge E., Chizhikov, Vladimir E., Czirjak, Gabor A., Fenton, M. Brock, Gilbert, Amy T., Navara, Kristen J., Recuenco, Sergio E., Simmons, Nancy B., Streicker, Daniel, Volokhov, Dmitriy V.   +13 more
core   +3 more sources

Improving statistical inference on pathogen densities estimated by quantitative molecular methods: malaria gametocytaemia as a case study [PDF]

, 2015
BACKGROUND: Quantitative molecular methods (QMMs) such as quantitative real-time polymerase chain reaction (q-PCR), reverse-transcriptase PCR (qRT-PCR) and quantitative nucleic acid sequence-based amplification (QT-NASBA) are increasingly used to ...
A Gelman, André Lin Ouédraogo, B Hoadley, C Eisenhart, C Fraser, C Osborne, CE McCulloch, Cornelus Hermsen, D Lunn, DJ Lunn, DJ Spiegelhalter, DL Massart, EC Fieller, F Ferre, FA Graybill, G Marsaglia, GK Shulka, HG Niesters, HS Mubarak El, J Jiang, J Wain, JF Cohen, JH McCulloch, JM Ruijter, JN Miller, JO Beer De, JS Murray, JS Yuan, K Danzer, K Khairnar, KK Lai, LC Okell, LJ Naszódi, M Plummer, M Sivaganesan, M Woodhead, Martin Walker, María-Gloria Basáñez, NM Ferguson, P Schneider, P Schneider, P Vankeerberghen, PF Mens, R Wampfler, S Nadarajah, SA Bustin, SA Bustin, SA Fiscus, T Nolan, T Ponnudurai, TD Schmittgen, Teun Bousema, Thomas S Churcher, TS Churcher, World Health Organization, Y Karlen, YW Tang   +56 more
core   +4 more sources

Investigating bacteriophages targeting the opportunistic pathogen Acinetobacter baumannii [PDF]

, 2020
The multi-drug resistance of the opportunistic pathogen Acinetobacter baumannii is of growing concern, with many clinical isolates proving to be resistant to last resort as well as front line antibiotic treatments.
Christie, Gabrielle S., Dowson, Christopher G., Leungtongkam, Udomluk, Millard, Andrew D., Moat, John, Sagona, Antonia P., Sitthisak, Sutthirat, Smith, Sophie, Styles, Kathryn, Thummeepak, Rapee, Wellington, Elizabeth M. H.   +10 more
core   +1 more source

Viral pathogens [PDF]

Haemophilia, 2010
Summary.  Despite continuous improvement in safety and purity of blood products for individuals with haemophilia, transmissible agents continue to affect individuals with haemophilia. This chapter addresses three viral pathogens with significant clinical impact: HIV, hepatitis C and parvovirus B19.
M V, Ragni, K E, Sherman, J A, Jordan
openaire   +2 more sources

Praziquantel treatment after Schistosoma japonicum infection maintains hepatic insulin sensitivity and improves glucose metabolism in mice

Parasites & Vectors, 2017
Background Epidemiological studies in China have revealed that Schistosoma japonicum infection is inversely correlated with metabolic syndrome, even after repeated chemotherapy with praziquantel (PZQ). We investigated the effect of chronic S.
Xiaofeng Luo, Yuxiao Zhu, Ran Liu, Jingwei Song, Fan Zhang, Wenyue Zhang, Zhipeng Xu, Min Hou, Bingya Yang, Lin Chen, Minjun Ji   +10 more
doaj   +1 more source

Transcription factor FTZ-F1 regulates mosquito cuticular protein CPLCG5 conferring resistance to pyrethroids in Culex pipiens pallens

Parasites & Vectors, 2020
Background Culex pipiens pallens poses a serious threat to human health because of its widespread distribution, high carrier capacity for several arboviruses, frequent human-biting, and growth in urban environments.
Yang Xu, Xiaoshan Yang, Xiaohong Sun, Xixi Li, Zhihan Liu, Qi Yin, Lei Ma, Dan Zhou, Yan Sun, Bo Shen, Changliang Zhu   +10 more
doaj   +1 more source

PECTOPLATE: the simultaneous phenotyping of pectin methylesterases, pectinases and oligogalacturonides in plants during biotic stresses [PDF]

, 2015
Degradation of pectin, a major component of plant cell wall, is important for fungal necrotrophs to achieve a successful infection. The activities of pectin methylesterases (PMEs) from both plants and pathogens and the degree and pattern of pectin ...
LIONETTI, VINCENZO
core   +2 more sources

MicroRNA-989 targets 5-hydroxytryptamine receptor1 to regulate ovarian development and eggs production in Culex pipiens pallens

Parasites & Vectors, 2023
Background Female mosquitoes need a blood meal after mating for their eggs to develop, and this behavior leads to the spread of pathogens. Therefore, understanding the molecular regulation of reproduction in female mosquitoes is essential to control ...
Junnan Zheng, Jingwei Xu, Ruiming Zhang, Jiajia Du, Huan Wang, Jinze Li, Dan Zhou, Yan Sun, Bo Shen   +8 more
doaj   +1 more source