Results 41 to 50 of about 4,236 (237)

Physiological Indicators of Pathologic Video Game Use in Adolescence

open access: yesJournal of Adolescent Health, 2015
Pathologic video game use (PVGU) has been associated with a host of negative psychological, physical, and social outcomes during adolescence; however, little research has examined physiological predictors of such use. The purpose of the study was to examine physiological predictors of the development of PVGU across adolescence.The article involves a 1 ...
Sarah M, Coyne   +5 more
openaire   +3 more sources

Macrophage TRIM21 Inhibition Ameliorates Murine Acute Pancreatitis via PHB2‐Mediated Mitochondrial Stabilization

open access: yesAdvanced Science, EarlyView.
Macrophage‐derived TRIM21 drives the progression of AP via ubiquitin‐proteasome‐mediated degradation of PHB2, leading to impaired PHB2‐mediated mitophagy. Therefore, accumulation of cytosolic mtDNA hyperactivates the cGAS‐STING signaling axis, thereby amplifying inflammatory cascades.
Yansong Xu   +7 more
wiley   +1 more source

Integrating Human Intestinal Organoids into FDA'S New Approach Methodologies for Drug Discovery

open access: yesAdvanced Science, EarlyView.
Illustration summarizes how human intestinal organoids (HIOs) are becoming transformative in preclinical research. Preclinical drug discovery pipelines often rely on animal models for ADMET studies, even though interspecies ADME gaps, poor external validity, and high attrition rates are common.
Debarun Patra   +6 more
wiley   +1 more source

Daily stress and gaming – an ambulatory assessment study in individuals with pathological, risky, and non-problematic gaming behavior

open access: yesActa Psychologica
Stress is considered a relevant factor in the development and maintenance of not only substance-related addictions but also behavioral addictions. Against this background, the current study investigated the association between daily stress and gaming use
Anna M. Schmid   +12 more
doaj   +1 more source

Prevalence and Risk Factors for Internet Gaming Disorder (IGD) in a sample of 5,979 Italian Online Gamers

open access: yesMediterranean Journal of Clinical Psychology, 2020
Background: The prevalence of Internet Gaming Disorder (IGD) in the Italian population of gamers is unknown. Several risk factors, including time spent playing (TSP), are proposed as an epiphenomenon of emotional dysregulation.
Laura Ferraro   +10 more
doaj   +1 more source

Perceptions of adolescents concerning pathological video games use: a qualitative study [PDF]

open access: yesLa Presse Médicale Open, 2020
Abstract Background Video gaming is one of the main recreational activities of children and adolescents. The American Psychiatric Association and the World Health Organization recently proposed diagnostic criteria for a pathological use of video games.
Isabelle Cisamolo   +4 more
openaire   +1 more source

Large Language Model‐Based Chatbots in Higher Education

open access: yesAdvanced Intelligent Systems, Volume 7, Issue 3, March 2025.
The use of large language models (LLMs) in higher education can facilitate personalized learning experiences, advance asynchronized learning, and support instructors, students, and researchers across diverse fields. The development of regulations and guidelines that address ethical and legal issues is essential to ensure safe and responsible adaptation
Defne Yigci   +4 more
wiley   +1 more source

Refining Measures for Assessing Problematic/Addictive Digital Gaming Use in Clinical and Research Settings

open access: yesBehavioral Sciences, 2015
Problematic or addictive digital gaming (including all types of electronic devices) can and has had extremely adverse impacts on the lives of many individuals across the world.
Kyle Faust, David Faust
doaj   +1 more source

Roadmap on Artificial Intelligence‐Augmented Additive Manufacturing

open access: yesAdvanced Intelligent Systems, EarlyView.
This Roadmap outlines the transformative role of artificial intelligence‐augmented additive manufacturing, highlighting advances in design, monitoring, and product development. By integrating tools such as generative design, computer vision, digital twins, and closed‐loop control, it presents pathways toward smart, scalable, and autonomous additive ...
Ali Zolfagharian   +37 more
wiley   +1 more source

The predictor role of metacognition and emotion recognition in internet gaming disorder among late adolescents

open access: yesEuropean Psychiatry, 2021
Introduction Internet gaming is acknowledged as a common leisure activity among adolescents yet only a little known about the pscyhodevelopmental roots.
O. Aydın   +4 more
doaj   +1 more source

Home - About - Disclaimer - Privacy