Results 41 to 50 of about 4,628,126 (296)

RIG-I: a multifunctional protein beyond a pattern recognition receptor

open access: yesProtein & Cell, 2017
It was widely known that retinoic acid inducible gene I (RIG-I) functions as a cytosolic pattern recognition receptor that initiates innate antiviral immunity by detecting exogenous viral RNAs.
Xiao-xiao Xu   +5 more
doaj   +1 more source

Feasibility of Applying Helper-Dependent Adenoviral Vectors for Cancer Immunotherapy

open access: yesBiomedicines, 2014
Adenoviruses (Ads) infect a broad range of tissue types, and derived vectors have been extensively used for gene therapy. Helper-dependent Ad vectors (HDAds), devoid of viral coding sequences, allow for insertion of large or multiple transgenes in a ...
Lisa M. Farzad, Masataka Suzuki
doaj   +1 more source

Primary immunodeficiencies of pattern recognition receptors [PDF]

open access: yesJournal of Internal Medicine, 2012
AbstractPrimary immunodeficiencies (PIDs) are severe defects in the capacity of the host to mount a proper immune response, and are characterized by an increased susceptibility to infections. Although classical immunodeficiencies have been characterized based on broad defects in cell populations (e.g.
Netea, M.G.   +2 more
openaire   +3 more sources

Stage-specific sampling by pattern recognition receptors during Candida albicans phagocytosis.

open access: yesPLoS Pathogens, 2008
Candida albicans is a medically important pathogen, and recognition by innate immune cells is critical for its clearance. Although a number of pattern recognition receptors have been shown to be involved in recognition and phagocytosis of this fungus ...
Sigrid E M Heinsbroek   +5 more
doaj   +1 more source

Coordinated Role of Toll-Like Receptor-3 and Retinoic Acid-Inducible Gene-I in the Innate Response of Bovine Endometrial Cells to Virus

open access: yesFrontiers in Immunology, 2017
Bovine herpesvirus-4 (BoHV-4) and bovine viral diarrhea virus (BVDV) infect the uterus of cattle, often resulting in reduced fertility, or abortion of the fetus, respectively. Here, exposure of primary bovine endometrial cells to BoHV-4 or BVDV modulated
Luisa C. Carneiro   +10 more
doaj   +1 more source

Feature learning via partial differential equation with applications to face recognition

open access: yes, 2017
Feature learning is a critical step in pattern recognition, such as image classification. However, most of the existing methods cannot extract features that are discriminative and at the same time invariant under some transforms.
Fang, Cong   +7 more
core   +1 more source

Enhancing crop innate immunity: new promising trends

open access: yesFrontiers in Plant Science, 2014
Plants are constantly exposed to potentially pathogenic microbes present in their surrounding environment. Due to the activation of the pattern-triggered immunity (PTI) response that largely relies on accurate detection of pathogen- or microbe-associated
Pin-Yao eHuang, Laurent eZimmerli
doaj   +1 more source

Informative shape representations for human action recognition

open access: yes, 2006
Shape and kinematics are two important cues in human movement analysis. Due to real difficulties in extracting kinematics from videos accurately, this paper proposes to address the problem of human action recognition by spatiotemporal shape analysis ...
Liang Wang   +3 more
core   +1 more source

Identifying the Patterns of Pattern Recognition Receptors [PDF]

open access: yesImmunity, 2018
Intestinal homeostasis requires microbial recognition that results in appropriate responses to commensals and pathogens. In this issue of Immunity, Price et al. (2018) map the in vivo expression of five toll-like receptors (TLR) in intestinal epithelia, revealing distinct spatio-temporal expression patterns that shape responses to TLR ligands.
Andrea A, Hill, Gretchen E, Diehl
openaire   +2 more sources

Plant pattern-recognition receptors

open access: yesTrends in Immunology, 2014
Plants are constantly exposed to would-be pathogens in their immediate environment. Yet, despite relying on innate immunity only, plants are resistant to most microbes. They employ pattern-recognition receptors (PRRs) for sensitive and rapid detection of the potential danger caused by microbes and pests. Plant PRRs are either surface-localized receptor
openaire   +4 more sources

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