Results 41 to 50 of about 246,190 (254)
Pattern‐recognition receptors in human eosinophils [PDF]
Immunology, 2012 SummaryThe pattern‐recognition receptor (PRR) family includes Toll‐like receptors (TLRs), nucleotide‐binding oligomerization domain (NOD) ‐like receptors (NLRs), RIG‐I‐like receptors (RLRs), C‐type lectin receptors (CLRs) and the receptor for advanced glycation end products (RAGE).
Anne Månsson, Kvarnhammar +1 more
openaire +2 more sources
Frontiers in Immunology, 2017 Bovine herpesvirus-4 (BoHV-4) and bovine viral diarrhea virus (BVDV) infect the uterus of cattle, often resulting in reduced fertility, or abortion of the fetus, respectively. Here, exposure of primary bovine endometrial cells to BoHV-4 or BVDV modulated
Luisa C. Carneiro +10 more
doaj +1 more source
Enhancing crop innate immunity: new promising trends
Frontiers in Plant Science, 2014 Plants are constantly exposed to potentially pathogenic microbes present in their surrounding environment. Due to the activation of the pattern-triggered immunity (PTI) response that largely relies on accurate detection of pathogen- or microbe-associated
Pin-Yao eHuang, Laurent eZimmerli
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Plant pattern-recognition receptors
Trends in Immunology, 2014 Plants are constantly exposed to would-be pathogens in their immediate environment. Yet, despite relying on innate immunity only, plants are resistant to most microbes. They employ pattern-recognition receptors (PRRs) for sensitive and rapid detection of the potential danger caused by microbes and pests. Plant PRRs are either surface-localized receptor
openaire +4 more sources
Structure Guided Design of Potent and Selective Ponatinib-Based Hybrid Inhibitors for RIPK1
Cell Reports, 2015 RIPK1 and RIPK3, two closely related RIPK family members, have emerged as important regulators of pathologic cell death and inflammation. In the current work, we report that the Bcr-Abl inhibitor and anti-leukemia agent ponatinib is also a first-in-class
Malek Najjar +13 more
doaj +1 more source
Virus sensing receptors in cellular infectivity of influenza A virus
Journal of Infection in Developing Countries, 2021 An innate immune response is essential to mobilize protective immunity upon the infection of respiratory epithelial cells with influenza A virus (IAV).
Shaihana Almatrrouk +4 more
doaj +1 more source
Evolutionary trajectory of pattern recognition receptors in plants
Nature Communications, 2023 Abstract Cell-surface receptors play pivotal roles in many biological processes, including immunity, development, and reproduction, across diverse organisms. How cell-surface receptors evolve to become specialised in different biological processes remains elusive.
Bruno Pok Man Ngou +4 more
openaire +3 more sources
Pediatric Blood &Cancer, EarlyView.ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen +23 more
wiley +1 more source
Specific Pathogen Recognition by Multiple Innate Immune Sensors in an Invertebrate
Frontiers in Immunology, 2017 Detection of pathogens by all living organisms is the primary step needed to implement a coherent and efficient immune response. This implies a mediation by different soluble and/or membrane-anchored proteins related to innate immune receptors called ...
Guillaume Tetreau +5 more
doaj +1 more source
Mini-Review: Bioactivities of Bacterial Cell Envelopes in the Central Nervous System
Frontiers in Cellular and Infection Microbiology, 2020 During acute bacterial meningitis, recognition of the bacterial envelope by immune cells of the central nervous system (CNS) generates a robust response that is essential to clear bacteria.
William J. MacCain, Elaine I. Tuomanen
doaj +1 more source