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Therapeutic targeting of pattern-recognition receptors

International Immunopharmacology, 2006
Innate immune system could recognize the pathogen-associated molecular patterns by pattern-recognition receptors like Toll-like receptor (TLR) and nucleotide-binding oligomerisation domain (NOD) protein. Information regarding the structure and signalling pathways of TLRs and NODs could provide opportunities for new therapeutic approaches to modulate ...
openaire   +2 more sources

Pattern Recognition by NOD-Like Receptors

Nucleotide-binding oligomerization domain-like receptors (NLRs) are a family of cytosolic pattern recognition receptors (PRRs) and able to respond to conserved microbe-associated molecular patterns (MAMPs) and endogenous damage-associated molecular patterns (DAMPs).
Timo-Daniel, Voss   +2 more
openaire   +2 more sources

Pattern Recognition Receptors in Autoinflammation

2019
The immune system is essential for maintenance of tissue homeostasis. This task requires that immune cells detect and respond to dyshomeostatic states (when homeostasis has broken down) that can occur during invasion of the host with pathogenic microbes, after sterile trauma of tissues or during metabolic derangements.
Saavedra, Victor   +3 more
openaire   +2 more sources

WSA03 ‐ Pattern Recognition Receptors

European Journal of Immunology, 2009
AbstractNo ...
openaire   +1 more source

Pattern-recognition receptors are required for NLR-mediated plant immunity

Nature, 2021
Yiping Wang   +2 more
exaly  

Pattern recognition receptors

2022
Adrian L. Smith, Steven R. Fiddaman
openaire   +1 more source

Context-dependent functions of pattern recognition receptors in cancer

Nature Reviews Cancer, 2022
Si Ming Man, Brendan Jenkins
exaly  

Pattern recognition receptors as therapeutic targets for bacterial, viral and fungal sepsis

International Immunopharmacology, 2021
Koichi Yuki, Sophia Koutsogiannaki
exaly  

Pattern recognition receptors in Drosophila immune responses

Developmental and Comparative Immunology, 2020
Xiao-Qiang Yu, Yuzhen Lu
exaly  

The role of bacteria and pattern-recognition receptors in Crohn's disease

Nature Reviews Gastroenterology and Hepatology, 2011
Hazel Mitchell   +2 more
exaly  

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