Results 171 to 180 of about 16,461 (203)

PAX8 as a Potential Target for Ovarian Cancer: What We Know so Far

open access: yesOncoTargets and Therapy, 2022
The Fallopian tube epithelium harbors the origin cells for the majority of high-grade serous ovarian carcinomas (HGSCs), the most lethal form of gynecologic malignancies.
Mariastella Zannini
exaly   +2 more sources

PAX8 expression in cancerous and non-neoplastic tissue: a tissue microarray study on more than 17,000 tumors from 149 different tumor entities

open access: yesVirchows Archiv Fur Pathologische Anatomie Und Physiologie Und Fur Klinische Medizin
PAX8 plays a role in development of the thyroid, kidney, and the Wolffian and Mullerian tract. In surgical pathology, PAX8 immunohistochemistry is used to determine tumors of renal and ovarian origin, but data on its expression in other tumors are ...
Ronald Simon, Sarah Minner
exaly   +2 more sources

Methylation of Septin9, SRSF1, and PAX8 in Early Screening of Colorectal Cancer in the Population Undergoing Physical Examinations.

Clinical Laboratory, 2023
BACKGROUND The aim was to investigate the value of blood Septin9, SRSF1, and PAX8 gene methylation detection techniques in early screening of colorectal cancer (CRC).
Qiong-Zhen Li   +7 more
semanticscholar   +1 more source

Diagnostic roles of PAX8 immunohistochemistry in ovarian tumors.

Pathology, Research and Practice, 2023
OBJECTIVE This study aimed to elucidate the diagnostic roles of PAX8 immunohistochemistry in various ovarian tumors. METHODS We searched through the PubMed database and selected the eligible studies to perform the meta-analysis.
Jooyoung Kim   +4 more
semanticscholar   +1 more source

Diagnostic and prognostic implications of the PAX8–PPARγ translocation in thyroid carcinomas—a TMA-based study of 226 cases

open access: yesHistopathology, 2013
AIMS: Follicular thyroid carcinoma (FTC) has been a diagnostic challenge for decades. The PAX8-PPARγ rearrangement has been detected in FTC and classic papillary thyroid carcinomas (PTCs).
Aurel Perren   +2 more
exaly   +2 more sources

Immunohistochemical Expression of Carbonic Anhydrase 9 (CA9), Glucose Transporter 1 (GLUT1), and Paired Box 8 (PAX8) in von Hippel Lindau Disease-Related Lesions.

Human Pathology, 2022
von Hippel Lindau (VHL) disease occurs secondary to pathogenic alterations of the VHL tumor suppressor gene, manifesting with cysts and tumors in multiple organ systems.
K. Chatzopoulos, M. Aubry, Sounak Gupta
semanticscholar   +1 more source

Unusual Staining of Immunohistochemical Markers PAX8 and CDX2 in Breast Carcinoma: A Potential Diagnostic Pitfall.

Human Pathology, 2022
AIMS Knowing the sensitivity and specificity of tissue-specific immunohistochemical markers is crucial for accurate determination of the primary tumor site.
T. Shen   +13 more
semanticscholar   +1 more source

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