Results 1 to 10 of about 1,900,236 (234)

Circulating B cell and T cell activation states predict clinical outcomes in melanoma and reveal dynamic immune reinvigoration with checkpoint inhibitor immunotherapy [PDF]

Journal for ImmunoTherapy of Cancer
Background Nearly half of patients with melanoma do not respond to immune checkpoint inhibitors (CPIs) and many develop immune-related adverse events (irAEs), often forcing treatment discontinuation, and underscoring the need to predict and monitor ...
Yin Wu, Manuela Terranova-Barberio, Angela Clifford, Rebecca Adams, Sean Whittaker, Nadira Ali, Katie E Lacy, Sophia N Karagiannis, Thomas J Tull, Matthew Stodell, Hawys Lloyd-Hughes, Sophia Tsoka, Khushboo Sinha, Zena N Willsmore, Lucy Booth, Amanda Fitzpartick, Francisco Aguilar, Cynthia Bishop, Jahangir Sufi, Jenny L C Geh, Alastair D MacKenzie Ross, Claire S Daniel, Niwa Ali   +22 more
doaj   +2 more sources

Co-existent Ovarian Tuberculosis with Borderline Serous Cyst Adenoma in an Infertile Young Female: A Case Report [PDF]

Journal of Clinical and Diagnostic Research, 2022
Genital tuberculosis involving the ovary in young non immunocompromised females is rare, and its coexistence with serous neoplasm makes it even rare and diagnostically challenging.
Shweta Verma, Preeti Agarwal, Mithilesh, Nancy Gupta, Vandana Solanki   +4 more
doaj   +1 more source

9.IMMUNOHISTOCHEMICAL EXPRESSIONS OF PAX8 IN OVARIAN SURFACE EPITHELIAL TUMORS

The Iraqi Journal of Medical Sciences, 2018
Background: PAX8 is a nuclear transcription factor with limited expression in normal and neoplastic tissues, it has the potential to induce tumorigenesis and is expressed in a tissue during neoplastic transformation.
Samar A. Al-Shami, Ban J. Qasim, Ahmed M. Hassan   +2 more
doaj   +6 more sources

Sporadic hemangioblastoma of the kidney: a clinicopathologic study of three cases and a literature review

Journal of International Medical Research, 2021
Much attention has been paid to renal hemangioblastoma, but there are still challenges in its differential diagnosis. Three cases (2 men, 1 woman; age: 40–56 years) presented with renal tumors.
Yanmei Xu, Xuehua Ma, Yong Ma, Juan Li, Renya Zhang, Xiaomei Li   +5 more
doaj   +1 more source

An Intrarenal Adrenocortical Carcinoma Arising in an Adrenal Rest [PDF]

Journal of Pathology and Translational Medicine, 2018
We describe a case of a 61-year-old Korean man who was diagnosed with renal cell carcinoma that was discovered on abdominopelvic computed tomography obtained after the patient complained of back pain. A radical nephrectomy was performed, and the surgical
Ji Hee Lee, Young Deuk Choi, Nam Hoon Cho   +2 more
doaj   +1 more source

ERN1 knockdown modifies the effect of glucose deprivation on homeobox gene expressions in U87 glioma cells

Endocrine Regulations, 2020
Objective. The aim of the present investigation was to study the expression of genes encoding homeobox proteins ZEB2 (zinc finger E-box binding homeobox 2), TGIF1 (TGFB induced factor homeobox 1), SPAG4 (sperm associated antigen 4), LHX1 (LIM homeobox 1),
Tsymbal Dariia O., Minchenko Dmytro O., Khita Olena O., Rudnytska Olha V., Viletska Yulia M., Lahanovska Yulia O., He Qiuxia, Liu Kechun, Minchenko Oleksandr H.   +8 more
doaj   +1 more source

KRAS Mutation in Serous Borderline Tumor of the Testis: Report of a Case and Review of the Literature

Case Reports in Urology, 2020
Ovarian-like epithelial tumors of the testis, including serous borderline tumors, are rare entities. We report the case of a 60-year-old man with a left intratesticular mass who had a radical orchidectomy.
Sarah Bouri, Jean-Christophe Noël, Xavier Catteau, Walid Al Hajj Obeid, Ilyas Svistakov, Thierry Roumeguère, Nicky D’Haene, Sandrine Rorive   +7 more
doaj   +1 more source

Effect of thermal manipulation during embryogenesis on gene expression of myogenic upstream activation factors pre- and post-hatch in broilers

Indian Journal of Animal Sciences, 2023
This study aimed to determine the optimum timing of embryonic thermal manipulation (TM) that may result in improvement of mRNA expression of myogenic upstream activation factors viz.
ABDELHAFEED DALAB, ABDELHAY ALI, THNIAN AL-THNIAN, SAEED Y AL-RAMADAN, KHALID ALKHODAIR   +4 more
doaj   +1 more source

Metastatic appendiceal mucinous adenocarcinoma presenting as bilateral ovarian masses mimicking advanced ovarian cancer: a case report [PDF]

The Ewha Medical Journal
Appendiceal mucinous adenocarcinoma is a rare gastrointestinal malignancy that may metastasize to the ovaries and closely mimic advanced primary ovarian cancer, creating diagnostic and therapeutic challenges.
Naina Kumar, Gunvanti Rathod, Annapurna Srirambhatla, Mishu Mangla, Nireesha Bukke, Pooja Tejappa Rathod   +5 more
doaj   +1 more source

Sinonasal renal cell-like adenocarcinoma with EGFR overexpression of the maxillary sinus: Report of a high-grade case and a review of the literature

Human Pathology: Case Reports, 2020
Sinonasal renal cell-like adenocarcinoma (SRCLA), which is an extremely rare but established entity, belongs to the non-salivary gland type of low-grade adenocarcinomas arising from the sinonasal tract. We report a case of high-grade SRCLA.
Kimihide Kusafuka, Tetsuro Onitsuka, Tadashi Terada   +2 more
doaj   +1 more source