Results 1 to 10 of about 16,461 (203)

PAX8 modulates the tumor microenvironment of high grade serous ovarian cancer through changes in the secretome

open access: yesNeoplasia: An International Journal for Oncology Research, 2023
High grade serous ovarian cancer (HGSC) arises from the fimbriated end of the fallopian tube epithelium (FTE), and in some cases, the ovarian surface epithelium (OSE). PAX8 is a commonly used biomarker for HGSC and is expressed in ∼90% of HGSC.
Amrita Salvi   +6 more
doaj   +3 more sources

RETRACTED ARTICLE: PAX8-AS1 knockdown facilitates cell growth and inactivates autophagy in osteoblasts via the miR-1252-5p/GNB1 axis in osteoporosis

open access: yesExperimental and Molecular Medicine, 2021
Osteoporosis (OP) is the most common systematic bone disorder among elderly individuals worldwide. Long noncoding RNAs (lncRNAs) are involved in biological processes in various human diseases.
Caiqiang Huang   +7 more
doaj   +2 more sources

DCTN2 and PAX8 levels in prostatic carcinoma tissues and their relationship with clinicopathological features and prognosis. [PDF]

open access: yesFront Oncol
ObjectiveTo investigate the levels of dynactin 2 (DCTN2) and paired box gene 8 (PAX8) in prostatic carcinoma (PCa) tissues and their relationship with clinicopathological features and prognosis.MethodsA total of 103 patients with PCa admitted between ...
He X, Zhu H, Fan D, Deng X, Huang Y.
europepmc   +2 more sources

Neuropilin-2 Is a Newly Identified Target of PAX8 in Thyroid Cells. [PDF]

open access: yesPLoS ONE, 2015
PAX8 is a transcription factor essential for thyroid gland development, as well as for the maintenance of the thyroid differentiated state in the adult.
Valeria Lucci   +2 more
doaj   +2 more sources

PAX8 Expression in the Crystalline Lens and Lens-Derived Lesions

open access: yesOphthalmology Science, 2021
Purpose: To evaluate PAX8 expression by immunohistochemistry in the normal pediatric and adult crystalline lens and to assess the usefulness of PAX8 immunohistochemical stain in the diagnosis of morphologically challenging lesions of lenticular origin ...
Ralph C. Eagle   +2 more
exaly   +3 more sources

SOX13 dependent PAX8 expression promotes the proliferation of gastric carcinoma cells

open access: yesArtificial Cells, Nanomedicine and Biotechnology, 2019
PAX8 is identified as a regulator in the pathogenesis of human tumours and an indicator of the prognosis for patients. However, the role of PAX8 on proliferation in gastric cancer have not been studied.
Su-Xia Luo
exaly   +3 more sources

CCDC80 suppresses high-grade serous ovarian cancer migration via negative regulation of B7-H3. [PDF]

open access: yesMol Oncol
Paired box protein Pax‐8 (PAX8) is a critical lineage marker and master regulator of transcription in high‐grade serous ovarian carcinoma (HGSC)—the most common subtype of epithelial ovarian cancer—driving cell proliferation and migration and resisting ...
Saleh A   +12 more
europepmc   +2 more sources

Evaluation of cell blocks from effusion specimens in Gynecologic Oncopathology: An experience of 220 cases, diagnosed at a Tertiary Cancer Referral Center

open access: yesIndian Journal of Pathology and Microbiology, 2020
One of the common indications of ascitic fluid examination in gynecological oncopathology is the detection and classification of malignant cells, especially in cases of clinically suspicious tubo-ovarian masses. The present study was undertaken to assess
Bharat Rekhi   +8 more
doaj   +1 more source

Clinicopathological study of sarcomatoid renal cell carcinoma in animals in East Java, Indonesia, from 2017 to 2022

open access: yesOpen Veterinary Journal, 2023
Background: Renal cell carcinoma (RCC) is common cancer derived from the renal epithelium. One of the rarest cases of RCC is sarcomatoid RCC (sRCC). The occurrence of sRCC in animals is not clearly demonstrated.
Yos Adi Prakoso   +3 more
doaj   +1 more source

Analysis of PAX8 immunohistochemistry in lung cancers: a meta-analysis [PDF]

open access: yesJournal of Pathology and Translational Medicine, 2020
Background In this meta-analysis, we aimed to evaluate the PAX8 immunohistochemical expressions in primary lung cancers and metastatic cancers to the lung. Methods We identified and reviewed relevant articles from the PubMed databases.
Jae Han Jeong, Nae Yu Kim, Jung-Soo Pyo
doaj   +1 more source

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