Results 1 to 10 of about 10,778 (133)

PAX8 modulates the tumor microenvironment of high grade serous ovarian cancer through changes in the secretome

Neoplasia, 2023
High grade serous ovarian cancer (HGSC) arises from the fimbriated end of the fallopian tube epithelium (FTE), and in some cases, the ovarian surface epithelium (OSE). PAX8 is a commonly used biomarker for HGSC and is expressed in ∼90% of HGSC.
Laura Hardy, Stephanie Cologna, Joanna Burdette   +2 more
exaly   +3 more sources

PAX8 Expression in the Crystalline Lens and Lens-Derived Lesions

Ophthalmology Science, 2021
Purpose: To evaluate PAX8 expression by immunohistochemistry in the normal pediatric and adult crystalline lens and to assess the usefulness of PAX8 immunohistochemical stain in the diagnosis of morphologically challenging lesions of lenticular origin ...
Hardeep Singh Mudhar, Tatyana Milman
exaly   +3 more sources

SOX17/PAX8 dual immunohistochemical expression in the diagnosis of Müllerian carcinomas [PDF]

Diagnostic Pathology
Background Metastatic Müllerian carcinomas, including endometrial and ovarian adenocarcinomas, are challenging to diagnose due to factors like similar malignancies, insufficient clinical history, multiorgan dissemination, and small tumor specimens ...
Manar Moustafa, Marwa Ahmed Mohamed Abdalrahman, Heba Mahmoud Abdelgeleel   +2 more
doaj   +2 more sources

Evaluation of cell blocks from effusion specimens in Gynecologic Oncopathology: An experience of 220 cases, diagnosed at a Tertiary Cancer Referral Center

Indian Journal of Pathology and Microbiology, 2020
One of the common indications of ascitic fluid examination in gynecological oncopathology is the detection and classification of malignant cells, especially in cases of clinically suspicious tubo-ovarian masses. The present study was undertaken to assess
Bharat Rekhi, Srushti Karmarkar, Chhavi Gupta, Kedar K Deodhar, Santosh Menon, Saleem Pathuthara, Amita Maheshwari, T S Shylasree, Sudeep Gupta   +8 more
doaj   +1 more source

RETRACTED ARTICLE: PAX8-AS1 knockdown facilitates cell growth and inactivates autophagy in osteoblasts via the miR-1252-5p/GNB1 axis in osteoporosis

Experimental and Molecular Medicine, 2021
Osteoporosis (OP) is the most common systematic bone disorder among elderly individuals worldwide. Long noncoding RNAs (lncRNAs) are involved in biological processes in various human diseases.
Caiqiang Huang, Runguang Li, Changsheng Yang, Rui Ding, Qingchu Li, Denghui Xie, Rongkai Zhang, Yiyan Qiu   +7 more
doaj   +1 more source

Clinicopathological study of sarcomatoid renal cell carcinoma in animals in East Java, Indonesia, from 2017 to 2022

Open Veterinary Journal, 2023
Background: Renal cell carcinoma (RCC) is common cancer derived from the renal epithelium. One of the rarest cases of RCC is sarcomatoid RCC (sRCC). The occurrence of sRCC in animals is not clearly demonstrated.
Yos Adi Prakoso, Sitarina Widyarini, Fradika Cahya Faresy, Yudha Sapto Utomo   +3 more
doaj   +1 more source

Neuropilin-2 Is a Newly Identified Target of PAX8 in Thyroid Cells. [PDF]

PLoS ONE, 2015
PAX8 is a transcription factor essential for thyroid gland development, as well as for the maintenance of the thyroid differentiated state in the adult.
Valeria Lucci, Tina Di Palma, Mariastella Zannini   +2 more
doaj   +1 more source

Analysis of PAX8 immunohistochemistry in lung cancers: a meta-analysis [PDF]

Journal of Pathology and Translational Medicine, 2020
Background In this meta-analysis, we aimed to evaluate the PAX8 immunohistochemical expressions in primary lung cancers and metastatic cancers to the lung. Methods We identified and reviewed relevant articles from the PubMed databases.
Jae Han Jeong, Nae Yu Kim, Jung-Soo Pyo
doaj   +1 more source

Paired box 8 facilitates the c-MYC related cell cycle progress in TP53-mutation uterine corpus endometrial carcinoma through interaction with DDX5

Cell Death Discovery, 2022
As a molecular marker of the female reproductive system, Paired Box 8 is widely used in pathological diagnosis of gynecological tumors, but it is not clear whether its expression level is related to the development of uterine corpus endometrial carcinoma
Ping Qiu, Youkun Jie, Cheng Ma, Huifeng Chen, Yunna Qin, Kaijia Tu, Liqun Wang, Ziyu Zhang   +7 more
doaj   +1 more source

Genome-wide analysis of Pax8 binding provides new insights into thyroid functions

BMC Genomics, 2012
Background The transcription factor Pax8 is essential for the differentiation of thyroid cells. However, there are few data on genes transcriptionally regulated by Pax8 other than thyroid-related genes.
Ruiz-Llorente Sergio, de Pau Enrique Carrillo, Sastre-Perona Ana, Montero-Conde Cristina, Gómez-López Gonzalo, Fagin James A, Valencia Alfonso, Pisano David G, Santisteban Pilar   +8 more
doaj   +1 more source