Results 31 to 40 of about 10,828 (178)
Majalah Obstetri dan GinekologiHIGHLIGHTS • Ovarian cancer is a gynecological disease commonly encountered by women, and resistance to platinum therapy is a significant challenge in its management • PAX8 and CD117 have shown potential as predictors of resistance in ovarian cancer ...
Robby Rinaldi Widodo +4 more
doaj +1 more source
Diagnostics, 2022 Transcription factor PAX8, expressed during embryonic kidney development, has been previously detected in various kidney tumors. In order to investigate expression of PAX8 transcription factor in acute kidney injury (AKI) and chronic kidney diseases (CKD)
Maja Zivotic +9 more
doaj +1 more source
9.IMMUNOHISTOCHEMICAL EXPRESSIONS OF PAX8 IN OVARIAN SURFACE EPITHELIAL TUMORS
The Iraqi Journal of Medical Sciences, 2018 Background: PAX8 is a nuclear transcription factor with limited expression in normal and neoplastic tissues, it has the potential to induce tumorigenesis and is expressed in a tissue during neoplastic transformation.
Samar A. Al-Shami +2 more
doaj +6 more sources
A Cutaneous Ciliated Cyst Mımicking a Pilonidal Cyst [PDF]
Journal of Clinical and Diagnostic Research, 2018 Cutaneous Ciliated Cyst (CCC) is a benign tumor encountered especially in the upper extremities and the perineal area in young women after puberty. CCC is located in the subcutaneous tissue in deep dermis, and histologically, it is a single, unilocular ...
Seda Gun, Duygu Kuru, Levent Yıldız
doaj +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
PAX8 Distinguishes Diffuse Large B-Cell Lymphoma Mimicking Sarcoma
Case Reports in Pathology, 2017 PAX8 is important for embryogenesis of the thyroid, Müllerian system, and upper urinary/renal tract, and expression of PAX8 has been described in carcinomas from each of these sites.
Michelle S. Hirsch +1 more
doaj +1 more source
IMMUNOHISTOCHEMICAL EXPRESSIONS OF PAX8 IN OVARIAN SURFACE EPITHELIAL TUMORS
The Iraqi Journal of Medical Sciences, 2018 Background: PAX8 is a nuclear transcription factor with limited expression in normal and neoplastic tissues, it has the potential to induce tumorigenesis and is expressed in a tissue during neoplastic transformation.
Samar Al-Shami, Ban Qasim, Ahmed Hassan
doaj +1 more source
Scientific Reports, 2023 The genetic and epigenetic architecture of clinical and subclinical hypothyroidism remains unclear. We investigated the impact of long noncoding RNA (LncRNA)-PAX8-AS1 and LAIR-2 genetic variants on the susceptibility to clinical and subclinical ...
Omar M. Elsayed +4 more
doaj +1 more source
eLife, 2019 PAX8 is a prototype lineage-survival oncogene in epithelial ovarian cancer. However, neither its underlying pro-tumorigenic mechanisms nor potential therapeutic implications have been adequately elucidated. Here, we identified an ovarian lineage-specific
Kaixuan Shi +11 more
doaj +1 more source
Diagnostic Cytopathology, EarlyView.ABSTRACT Nephrogenic adenoma (NA) is a benign lesion of the genitourinary tract that may mimic malignancy both clinically and histologically. The fibromyxoid variant (FMNA), characterized by spindled cells in myxoid stroma, presents additional diagnostic challenges due to its rarity and overlapping features with renal cell carcinoma (RCC).
Jodi Gedallovich +4 more
wiley +1 more source